Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Identification of new genetic risk factors and protein markers affecting susceptibility to non-small cell lung cancer in a Polish population

2014/15/B/NZ5/03517

Keywords:

non-small cell lung cancer genetics immunohistochemistry ELISA

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_1: Etiology of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Piotr Kuśnierczyk 

Number of co-investigators in the project: 11

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 825 500 PLN

Project start date (Y-m-d): 2015-07-23

Project end date (Y-m-d): 2020-01-22

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zamrażarka niskotemperaturowa (40 000 PLN)
  2. 6-kanałowy aparat do reakcji PCR w czasie rzeczywistym (180 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (5)
  1. The association of HLA/KIR genes with non-small cell lung cancer (adenocarcinoma) in a Han Chinese population
    Authors:
    Yingfu Li, Shuyuan Liu, Chao Hong, Qianli Ma, Fang Tan, Chengxiu Liu, Piotr Kuśnierczyk, Chuanyin Li, Li Shi and Yufeng Yao
    Academic press:
    Journal of Cancer (rok: 2019, tom: 10, strony: 4731-4738), Wydawca: Ivyspring International Publisher
    Status:
    Published
    DOI:
    10.7150/jca.33566 - link to the publication
  2. Polymorphisms of Antigen-Presenting Machinery Genes in Non-Small Cell Lung Cancer: Different Impact on Disease Risk and Clinical Parameters in Smokers and Never-Smokers
    Authors:
    Andrzej Wiśniewski, Maciej Sobczyński, Konrad Pawełczyk, Irena Porębska, Monika Jasek, Marta Wagner, Wanda Niepiekło-Miniewska, Aneta Kowal, Joanna Dubis, Natalia Jędruchniewicz and Piotr Kuśnierczyk
    Academic press:
    Frontiers in Immunology (rok: 2021, tom: 12, strony: Article 664474, 1-17), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2021.664474 - link to the publication
  3. Endoplasmic reticulum aminopeptidases as a double-faced tool to increase or decrease efficiency of antigen presentation in health and disease
    Authors:
    Piotr Kuśnierczyk, Efstratios Stratikos
    Academic press:
    Human Immunology (rok: 2019, tom: 80, strony: 277-280), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.humimm.2019.03.011 - link to the publication
  4. Single Nucleotide Polymorphisms of the ERAP1 Gene and Risk of NSCLC: A Comparison of Genetically Distant Populations, Chinese and Caucasian
    Authors:
    Yufeng Yao, Andrzej Wiśniewski, Qiangli Ma, Aneta Kowal, Irena Porębska, Konrad Pawełczyk, Jiankun Yu, Joanna Dubis, Natalia Żuk, Yingfu Li, Li Shi, and Piotr Kuśnierczyk
    Academic press:
    Archivum Immunologiae et Therapiae Experimentalis (rok: 2016, tom: 64, Suppl. 1, strony: S117-S122), Wydawca: Birkhauser Publishers Ltd (Basel, CH, a part of Springer Publishers).
    Status:
    Published
    DOI:
    10.1007/s00005-016-0436-4 - link to the publication
  1. Comparison of associations of endoplasmic reticulum aminopeptidase 1 polymorphisms with non-small cell lung cancer in Poles and Chinese.
    Authors:
    Yufeng Yao, Andrzej Wiśniewski, Qiangli Ma, Aneta Kowal, Irena Porębska, Konrad Pawełczyk, Jiankun Yu, Joanna Dubis, Natalia Żuk, Yingfu Li, Li Shi, Piotr Kuśnierczyk
    Conference:
    The 10th East-West Immunogenetics Conference (rok: 2016, ), Wydawca: Arch. Immunol. Ther. Exp., Birkhauser Publishers Ltd (Basel, CH, a part of Springer Publishers).
    Data:
    konferencja 21-23 kwietnia 2016
    Status:
    Published
    DOI:
    link to the publication
  2. The Role of Antigen – Presenting Machinery Polymorphisms in Predisposition to Lung Cancer
    Authors:
    Yufeng Yao, Andrzej Wiśniewski, Qiangli Ma, Aneta Kowal, Irena Porębska, Konrad Pawełczyk, Jiankun Yu, Joanna Dubis, Natalia Żuk, Yingfu Li, Li Shi and Piotr Kuśnierczyk
    Conference:
    BIT's 2nd International Congress of Genetics-2017, Xi'an, Yunnan, Chiny (rok: 2017, ), Wydawca: BIT
    Data:
    konferencja 25-27.04.2017
    Status:
    Published
  3. SNPs of the ERAP1 gene: are they associated with non-small cell lung cancer in Poles or Chinese?
    Authors:
    Yufeng Yao, Andrzej Wiśniewski, Qiangli Ma, Aneta Kowal, Irena Porębska, Konrad Pawełczyk, Jiankun Yu, Joanna Dubis, Natalia Żuk, Yingfu Li, Li Shi, Piotr Kuśnierczyk
    Conference:
    V Polski Kongres Genetyki, Łódź (rok: 2016, ), Wydawca: Polskie Towarzystwo Genetyczne i Polskie Towarzystwo Genetyki Człowieka
    Data:
    konferencja 19-22.09.2016.
    Status:
    Published
    DOI:
    link to the publication
  4. Comparison of the distribution of ERAP1 single nucleotide polymorphisms in non-small cell lung cancer patients and healthy controls in Poland and China.
    Authors:
    Yufeng Yao, Andrzej Wiśniewski, Qiangli Ma, Aneta Kowal, Irena Porębska, Konrad Pawełczyk, Jiankun Yu, Joanna Dubis, Natalia Żuk, Yingfu Li, Li Shi, Piotr Kuśnierczyk
    Conference:
    ICI 2016 - International Congress of Immunology, Melbourne, Victoria, Australia (rok: 2016, ), Wydawca: ICI 2016 - International Congress of Immunology, Melbourne, Victoria, Australia
    Data:
    konferencja 21-26.08.2016.
    Status:
    Published
    DOI:
    link to the publication
  5. Polymorphisms of killer cell immunoglobulin-like receptors, endoplasmic reticulum aminopeptidases and human leukocyte antigen claass I genes in non-small cell lung cancer in Poles
    Authors:
    Andrzej Wiśniewski, Wanda Niepiekło-Miniewska, Łukasz Łaczmański, Ewa Passowicz-Muszyńska, Aneta Kowal, Irena Porębska, Konrad Pawełczyk, Joanna Dubis, Natalia Żuk, Piotr Kuśnierczyk
    Conference:
    Autoimmune, allergic, immunodeficiency and immunological havoc: modern diagnostic and treatment (rok: 2018, ), Wydawca: Uniwersytet Medyczny im. Daniela Halickiego, Lwów, Ukraina
    Data:
    konferencja 28.11.-1.12.2018
    Status:
    Published

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