Experimental and clinical study of CD151-regulated activity of FGFR2 in breast cancer progression
2012/06/M/NZ3/00023
Keywords
Descriptors
- NZ3_1: Biologia komórki
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego
Voivodeship: pomorskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 7
Call
HARMONIA 3 – announced on 2012-06-15
- Amount awarded
- 663 600 PLN
- Project start date
- 2013-03-27
- Project end date
- 2017-12-26
- Project duration
- 57 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (6)
-
Fibroblast growth factor signalling induces loss of progesterone receptor in breast cancer cells.
- Authors:
- Piasecka D, Kitowska K, Czaplinska D, Mieczkowski K, Mieszkowska M, Turczyk L, Skladanowski AC, Zaczek AJ, Biernat W, Kordek R, Romanska HM, Sadej R.
- Academic press:
- Oncotarget (year: 2016, volume: 7(52), pages: 86011-86025), Publisher: Impact Journals
- Status:
- Published
- DOI:
- 10.18632/oncotarget.13322 – link to the publication
-
CD151 regulates expression of FGFR2 in breast cancer cells via PKC-dependent pathways
- Authors:
- Sadej R, Lu X, Turczyk L, Novitskaya V, Lopez-Clavijo AF, Kordek R, Potemski P, Wakelam MJO, Romanska H, Fedor Berditchevski.
- Academic press:
- Journal of Cell Science (year: 2018, volume: 131, pages: pii: jcs220640), Publisher: The company of biologists
- Status:
- Published
- DOI:
- 10.1242/jcs.220640 – link to the publication
-
FGFR2-Driven Signaling Counteracts Tamoxifen Effect on ERα-Positive Breast Cancer Cells
- Authors:
- Turczyk L, Kitowska K, Mieszkowska M, Mieczkowski K, Czaplinska D, Piasecka D, Kordek R, Skladanowski AC, Potemski P, Romanska HM, Sadej R
- Academic press:
- Neoplasia (year: 2017, volume: 19, pages: 791-804), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.neo.2017.07.006 – link to the publication
-
Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration
- Authors:
- Dominika Czaplinska, Lukasz Turczyk, Alicja Grudowska, Magdalena Mieszkowska, Andrea D. Lipinska, Andrzej C. Skladanowski, Anna J. Zaczek, Hanna M. Romanska, Rafal Sadej
- Academic press:
- BBA - Molecular Cell Research (year: 2014, volume: 1843, pages: 2461–2470), Publisher: ELSEVIER
- Status:
- Published
- DOI:
- 10.1016/j.bbamcr.2014.06.022 – link to the publication
-
Lack of CD151/integrin alpha3beta1 complex is predictive of poor outcome in node–negative lobular breast carcinoma: opposing roles of CD151 in invasive lobular and ductal breast cancers
- Authors:
- Hanna M. Romanska, Piotr Potemski, Magdalena Krakowska, Magdalena Mieszkowska, Shalini Chaudhri, Radzisław Kordek, Robert Kubiak, Valerie Speirs, Andrew M. Hanby, Rafał Sadej, Fedor Berditchevski
- Academic press:
- British Journal of Cancer (year: 2015, volume: 113, pages: 1350-1357), Publisher: Nature Publishing Group
- Status:
- Published
- DOI:
- 10.1038/bjc.2015.344 – link to the publication
-
Interactions between FGFR2 and RSK2-implications for breast cancer prognosis
- Authors:
- Czaplinska D, Mieczkowski K, Supernat A, Skladanowski AC, Kordek R, Biernat W, Zaczek AJ, Romanska HM, Sadej R.
- Academic press:
- Tumor Biology (year: 2016, volume: 10, pages: 13721), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s13277-016-5266-9 – link to the publication