New mechanism of bisphenol A and its analogs action in the biology of ovarian cancer.
2013/09/B/NZ7/00405
Keywords
Descriptors
- NZ7_2: Zagrożenia środowiskowe
- NZ3_1: Biologia komórki
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
OPUS 5 – announced on 2013-03-15
- Amount awarded
- 536 000 PLN
- Project start date
- 2014-03-21
- Project end date
- 2017-03-20
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Komputer z drukarką. Cost: 6 000 PLN
- Spektrofotometr do pomiaru mikroobjętości NanoDrop 2000 z opragramowaniem. Cost: 62 000 PLN
Information in the final report
Publication in academic press/journals (4)
-
Adiponectin Reverses the Proliferative Effects of Estradiol and IGF-1 in Human Epithelial Ovarian Cancer Cells by Downregulating the Expression of Their Receptors
- Authors:
- Marta Hoffmann, Justyna Gogola, Anna Ptak
- Academic press:
- Hormones and Cancer (year: 2018, volume: 9, pages: 166-174), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s12672-018-0331-z – link to the publication
-
Stimulation of ovarian cell proliferation by tetrabromobisphenol A but not tetrachlorobisphenol A through G protein-coupled receptor 30
- Authors:
- Marta Hoffmann, Justyna Gogola, Małgorzata Kotula-Balak, Anna Ptak
- Academic press:
- Toxicology in vitro (year: 2017, volume: 54, pages: 54-59), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.tiv.2017.08.009 – link to the publication
-
Bisphenol A and its derivatives tetrabromobisphenol A and tetrachlorobisphenol A induce apelin expression and secretion in ovarian cancer cells through a peroxisome proliferator-activated receptor gamma-dependent mechanism
- Authors:
- Marta Hoffmann, Elzbieta Fiedor, Anna Ptak
- Academic press:
- Toxicology Letters (year: 2017, volume: 269, pages: 15-22), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.toxlet.2017.01.006 – link to the publication
-
Bisphenol A and its derivatives decrease expression of chemerin, which reverses its stimulatory action in ovarian cancer cells
- Authors:
- Marta Hoffmann, Agnieszka Rak, Anna Ptak
- Academic press:
- Toxicology Letters (year: 2018, volume: 291, pages: 61-69), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.toxlet.2018.04.004 – link to the publication
Articles in post-conference publications (2)
-
Bisphenol A and its halogenated derivatives induce apelin expression which acts as mitogenic factor in human epithelial ovarian cancer cell.
- Authors:
- Marta Hoffmann, Elzbieta Fiedor, Anna Ptak
- Conference:
- 36th International Symposium on Halogenated Persistent Organic Pollutants. DIOXIN 2016 (year: 2016, pages: 867-869), Publisher: Organohalogen Compounds
- Date:
- conference 28 sierpień - 2 wrzesień 2016
- Status:
- Published
-
ADIPOKINES SECRETED BY HUMAN OVARIAN CANCER CELLS PLAY AN IMPORTANT ROLE IN CANCER PROGRESSION BY INDUCTION CELLS PROLIFERATION.
- Authors:
- K. Kulczak, E. Fiedor, W. Natkaniec, A. Rak, A. Ptak
- Conference:
- 19th International Meeting of the European Society of Gynaecological Oncology (ESGO 2015) (year: 2015, pages: 1473), Publisher: Wolters Kluwer
- Date:
- conference 24-27 październik
- Status:
- Published
- DOI:
- link to the publication
Book publications / chapters in book publications (1)
-
The ovary as a target organ for bisphenol A toxicity.
- Authors:
- Anna Ptak, Marta Hoffmann, Agnieszka Rak
- Book:
- Bisphenol A (BPA) Exposure and Health Risks (year: 2017, volume: 1, pages: 57-73), Publisher: InTech
- Status:
- Published