Search results

1. Development of bioanalytical procedures to assess the effects of antidepressants on the neurovascular unit (NVU), taking…

Principal investigator: dr Agnieszka Żuchowska

Politechnika Warszawska

Call: SONATA BIS 15, Panel: ST4

2. Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the respon…

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Call: OPUS 22, Panel: HS6

3. Dual action of HBK-15 – unraveling cellular mechanisms underlying its fast antidepressant-like and procognitive effects

Principal investigator: dr hab. Karolina Anna Pytka

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA BIS 9, Panel: NZ7

4. The role of selected metabotropic glutamate receptors in the mechanism of rapid antidepressant effect of RS-ketamine and…

Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

Instytut Farmakologii PAN

Call: OPUS 14, Panel: NZ7

5. Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

Principal investigator: dr Anna Maria Rafało-Ulińska

Instytut Farmakologii PAN

Call: PRELUDIUM 13, Panel: NZ5

6. Role of oxidative stress and ceramide in the pathogenesis of depression and in the mechanizm of action of antidepressant…

Principal investigator: Justyna Józefa Brodowicz

Instytut Farmakologii PAN

Call: PRELUDIUM 12, Panel: NZ5

7. Evaluation of interactions of aripiprazole, the atypical amtipsychotic drug, with the selected antidepressants in the ra…

Principal investigator: dr hab. Zofia Maria Rogóż

Instytut Farmakologii PAN

Call: OPUS 12, Panel: NZ7

8. The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola…

Principal investigator: Karolina Sylwia Podkowa

Instytut Farmakologii PAN

Call: PRELUDIUM 10, Panel: NZ7

9. The role of inflammation, oxidative and nitrosative stress, tryptophan catabolites pathway and DNA base excision repair …

Principal investigator: dr hab. Tomasz Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 10, Panel: NZ7

10. Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio…

Principal investigator: prof. Irena Maria Nalepa

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ7

11. The application of a modern chromatographic platform with biodetection: HPLC-DAD/MAO A/ESI-TOF-MS in the antidepressant …

Principal investigator: dr hab. Wirginia Anna Kukuła-Koch

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Call: SONATA 9, Panel: NZ7

12. Selected antidepressants toxicity assessment based on in vitro studies of rat spermatocytes and mouse cell lines.

Principal investigator: Przemysław Paweł Sołek

Uniwersytet Rzeszowski, Wydział Biotechnologii

Call: PRELUDIUM 8, Panel: NZ7

13. Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet…

Principal investigator: dr Grzegorz Kreiner

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

14. Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap…

Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

15. The role of chemokines in the pathogenesis of depression and molecular mechanism of action of antidepressants.

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Call: OPUS 5, Panel: NZ7

16. Research on influence of antidepressant drugs on serum and brain levels of neurotrophins in rats, affected by the time d…

Principal investigator: dr Maciej Sławomir Kuśmider

Instytut Farmakologii PAN

Call: OPUS 4, Panel: NZ4

17. The role of CRH-BP protein in the regulation of the hypothalamic-pituitary-adrenal axis after antidepressant drugs treat…

Principal investigator: dr Joanna Solich

Instytut Farmakologii PAN

Call: OPUS 3, Panel: NZ4

18. Role of the endocannabionoid system in the pathogenesis of depression and in the mechanism of action of antidepressant d…

Principal investigator: prof. Małgorzata Maria Filip

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 3, Panel: NZ7

19. The role of GPR39 receptor in the mechanism of antidepressant action

Principal investigator: dr Katarzyna Młyniec

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 2, Panel: NZ7

20. Pharmacokinetic and pharmacodynamics modeling of antidepressants in a mechanistic approach for efficient therapy.

Principal investigator: prof. Filip Rybakowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: OPUS 29, Panel: NZ7

21. Modulation of 5-HT7 receptor signaling as common mechanism involved in the long-lasting antidepressant effects of typica…

Principal investigator: dr Barbara Wanda Chruścicka-Smaga

Instytut Farmakologii PAN

Call: SONATA 20, Panel: NZ7

22. Mechanisms of Antidepressant Action of Psilocybin: The Role of 5-HT2B-5-HT1A Receptor Dimerization and GSK-3β Activation…

Principal investigator: dr hab. Agata Faron-Górecka

Instytut Farmakologii PAN

Call: OPUS 27, Panel: NZ7

23. Dual Se-containing 5-HT1A and 5-HT7 biased agonists activating sigma-1 receptor as a hope of finding fast-acting antidep…

Principal investigator: prof. Karolina Anna Pytka

Uniwersytet Jagielloński

Call: OPUS 27, Panel: NZ7

24. Anti-neuroinflammatory and antidepressant activities of mycelial in vitro cultures of selected edible mushrooms enriched…

Principal investigator: Jan Patryk Lazur

Uniwersytet Jagielloński

Call: PRELUDIUM 23, Panel: NZ7

25. Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte…

Principal investigator: Dominika Kunachowicz

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Call: PRELUDIUM 23, Panel: NZ5

26. Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista…

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Call: OPUS 26, Panel: NZ7

27. The cross-talk between 5-HTR2A and mGluR2 as a window for antidepressant effects of psilocybin.

Principal investigator: prof. Andrzej Mikołaj Pilc

Instytut Farmakologii PAN

Call: OPUS 25, Panel: NZ7

28. Enhancement of antidepressant therapy by combined administration of hyperforin and ketamine: behavioral and molecular st…

Principal investigator: dr Bartłomiej Pochwat

Instytut Farmakologii PAN

Call: SONATA 17, Panel: NZ7

29. Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression

Principal investigator: prof. Krystyna Czesława Gołembiowska

Instytut Farmakologii PAN

Call: OPUS 19, Panel: NZ7

30. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor…

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Call: OPUS 18, Panel: NZ7

31. The influence of microplastics on the toxicity and fate of selected antidepressants

Principal investigator: prof. Grzegorz Leszek Nałęcz-Jawecki

Warszawski Uniwersytet Medyczny

Call: OPUS 18, Panel: NZ8

32. Modeling of quantitative structure-metabolic stability relationships as a tool to improve design of potential novel anti…

Principal investigator: prof. Tomasz Bączek

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 12, Panel: NZ7

33. Effect of modulation of the GPR39 zinc receptor on glutamatergic and gabaergic transmission in the context of antidepres…

Principal investigator: Gabriela Joanna Starowicz

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 11, Panel: NZ7

34. Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress…

Principal investigator: dr Ewa Izabela Trojan

Instytut Farmakologii PAN

Call: PRELUDIUM 9, Panel: NZ7

35. Molecular mechanism of action of antidepressant drugs in the in vitro model of contact allergy in the human cell line Ha…

Principal investigator: Katarzyna Curzytek

Instytut Farmakologii PAN

Call: PRELUDIUM 7, Panel: NZ6

36. Involvement of cyclooxygenase 2 in antidepressant-like effects of metabotropic glutamatergic receptors group I.

Principal investigator: dr Katarzyna Małgorzata Stachowicz

Instytut Farmakologii PAN

Call: SONATA 7, Panel: NZ7

37. The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal r…

Principal investigator: prof. Grzegorz Władysław Hess

Instytut Farmakologii PAN

Call: OPUS 6, Panel: NZ4

38. Synthesis and biological evaluation of pyrrolidine-2,5-dione derivatives as potential antidepressant agents.

Principal investigator: dr Andrzej Józef Chodkowski

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: OPUS 5, Panel: NZ7

39. Involvement of 5-HT1A receptor signal pathway in the antidepressant effect of zinc

Principal investigator: dr Bernadeta Szewczyk

Instytut Farmakologii PAN

Call: HARMONIA 4, Panel: NZ7

40. Metabolic stability and inhibition of P450 enzymes in combination with chemometric techniques as a tool for selection of…

Principal investigator: prof. Tomasz Bączek

Gdański Uniwersytet Medyczny, Wydział Farmcautyczny z Oddziałem Medycyny Laboratoryjnej

Call: OPUS 2, Panel: NZ1

41. The role of the immune checkpoints in the pathomechanism of depressive disorders.

Principal investigator: prof. Marta Wanda Kubera

Instytut Farmakologii PAN

Call: OPUS 22, Panel: NZ6

42. 3D printing as a tool to obtain transdermal microneedle systems with improved efficiency in the treatment of depressive …

Principal investigator: prof. Tomasz Zbigniew Osmałek

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: SONATA BIS 11, Panel: NZ7

43. Impact of pharmacogenetic profiles on depression treatment outcomes

Principal investigator: dr Małgorzata Maria Borczyk

Instytut Farmakologii PAN

Call: SONATINA 5, Panel: NZ2

44. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan…

Principal investigator: prof. Andrzej Mikołaj Pilc

Instytut Farmakologii PAN

Call: OPUS 19, Panel: NZ7

45. Novel pharmacological strategies for the treatment of depression

Principal investigator: dr hab. Katarzyna Młyniec

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 16, Panel: NZ7

46. Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i…

Principal investigator: dr Agnieszka Wioleta Jankowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 13, Panel: NZ7

47. Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p…

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Call: OPUS 13, Panel: NZ7

48. The importance of interaction between NMDA and AMPA receptors and scaffolding proteins in the excitatory synaptic in the…

Principal investigator: dr hab. Magdalena Jolanta Sowa-Kućma

Uniwersytet Rzeszowski, Kolegium Nauk Medycznych

Call: OPUS 11, Panel: NZ7

49. Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist…

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ7

50. Synthesis, physicochemical and pharmacological properties of new amide derivatives of 3,3-disubstituted pyrrolidine-2,5-…

Principal investigator: prof. Jolanta Maria Obniska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 6, Panel: NZ7

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