Search results

1. Deciphering RNA self-replication with quantum chemistry and machine learning.

Principal investigator: dr Rafał Szabla

Politechnika Wrocławska

Call: SONATA BIS 12, Panel: ST4

2. New methods for the determination of RNA secondary structure, tools towards studies biological activities of RNAs

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 2, Panel: NZ1

3. Photodamage and self-healing of primordial forms of DNA and RNA.

Principal investigator: dr Rafał Kazimierz Szabla

Politechnika Wrocławska

Call: OPUS 19, Panel: ST4

4. Thermodynamics of modified RNAs. Impact of RNA modifications on structure and function of natural RNA and vaccine-type i…

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 23, Panel: ST4

5. Double stranded probes, in which both oligonucleotide components hybridize according to the Hoogsteen's interactions, an…

Principal investigator: dr hab. Piotr Jerzy Guga

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 10, Panel: ST5

6. Thermodynamic parameters and rules towards the determination of RNA folding in in vivo-like conditions. RNA folding pred…

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 17, Panel: ST4

7. Determination of the influence of 5' end of RNA modifications and nucleotide or amino acid sequence on the electrostatic…

Principal investigator: Urszula Anna Budniak

Uniwersytet Warszawski, Wydział Chemii

Call: PRELUDIUM 11, Panel: ST4

8. New methods for mRNA 5' end labeling and examples of their application in studies on RNA metabolism and searching for in…

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 5, Panel: ST5

9. Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec…

Principal investigator: prof. Elżbieta Beata Kierzek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 21, Panel: NZ1

10. Tecto-RNA nano-structures for gene expression regulation in a model system

Principal investigator: dr hab. Arkadiusz Chworoś

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 10, Panel: ST5

11. High throughput microfluidic system for fast determination of the equilibrium constant for biomolecular complexes: appli…

Principal investigator: prof. Robert Hołyst

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: PRELUDIUM BIS 2, Panel: ST4

12. Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN…

Principal investigator: dr Dorota Gudanis-Sobocińska

Instytut Chemii Bioorganicznej PAN

Call: SONATA 16, Panel: ST4

13. Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping …

Principal investigator: dr hab. Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Call: OPUS 16, Panel: ST5

14. Studies on influence of cytochrome c on oxidative damage of 2-thiouridines built in an RNA chain

Principal investigator: Anna Maria Chwiałkowska

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: PRELUDIUM 9, Panel: ST5

15. RNA hybrid duplex-quadruplex structures with dual functionality as a new tool for silecing of gene expression

Principal investigator: prof. Zofia Janina Gdaniec

Instytut Chemii Bioorganicznej PAN

Call: OPUS 7, Panel: ST5

16. Injectable and RNA-releasing nanofibrous microcarriers for intervertebral disc regeneration

Principal investigator: dr Paweł Nakielski

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Call: SONATA BIS 13, Panel: ST5

17. Studies on receptor layers formed by DNA and RNA aptamers in respect of their potential application in biosensors for de…

Principal investigator: dr Marta Maria Jarczewska

Politechnika Warszawska

Call: PRELUDIUM 8, Panel: ST4

18. Mitochondrial RNA decay and surveillance - comprehensive interdisciplinary studies.

Principal investigator: dr hab. Marcin Piotr Nowotny

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: SYMFONIA 2, Panel: NZ1

19. Machine-learning a new generation of force fields for the atomistic simulations of RNA

Principal investigator: dr Miłosz Wieczór

Politechnika Gdańska

Call: OPUS 29, Panel: ST4

20. Development of HTS method based on fluorescently labelled guanosine analogues: novel route for RNA (guanosine-N7)-methyl…

Principal investigator: Renata Kasprzyk

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: PRELUDIUM 12, Panel: ST4

21. Design and synthesis of new rifampicin analogs as a source of effective bacterial RNA polymerase inhibitors

Principal investigator: dr hab. Piotr Przybylski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Call: OPUS 2, Panel: ST5

22. Chromatographic determination of nucleic acids (DNA, RNA) and their constituents (nucleosides, nucleotides, oligonuceoti…

Principal investigator: dr Sylwia Studzińska

Uniwersytet Mikołaja Kopernika, Wydział Chemii, Katedra Chemii Środowiska i Bioanalityki

Call: SONATA 1, Panel: ST4

23. P-Stereodefined phosphorothioate analogs of DNA containing within nucleobases modifications preventing Watson-Crick base…

Principal investigator: dr Anna Maciaszek

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 6, Panel: ST5

24. Stereodefined phosphorothioate analogs of DNA with incorporated LNA-type nucleosides - synthesis and properties of compl…

Principal investigator: dr hab. Piotr Jerzy Guga

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 2, Panel: ST5

25. Interactions of peptide nucleic acids with biologically relevant RNA motifs

Principal investigator: dr hab. Joanna Dominika Trylska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 3, Panel: NZ1

26. Structure defined oligonucleotides for revealing fundamental insights into structure and function of RNAs

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej PAN

Call: MAESTRO 4, Panel: ST5

27. Modified chlorophyll derivatives and its RNA hybrid conjugates for modern photomedicine

Principal investigator: Michał Kotkowiak

Politechnika Poznańska, Wydział Fizyki Technicznej

Call: PRELUDIUM 6, Panel: NZ7

28. Why Nature introduced selenium to wobble nucleosides in transfer RNA?

Principal investigator: prof. Barbara Czesława Nawrot

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 15, Panel: ST5

29. Application of LCMS to quantitative analysis of composition of in vitro transcribed RNAs containing chemically modified …

Principal investigator: Dominika Strzelecka

Uniwersytet Warszawski, Wydział Fizyki

Call: PRELUDIUM 12, Panel: ST4

30. Thermodynamic insights into design of functionally optimized modified siRNAs and their experimental verification.

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

Call: SONATA BIS 3, Panel: NZ1

31. Designing modified mRNAs as vaccines and therapeutic protein carriers. Studies on their immunogenicity in the context of…

Principal investigator: dr Renata Joanna Grzela

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 17, Panel: NZ1

32. Synthesis and structural/biophysical studies of model mRNA/mt-tRNA oligomers to evaluate the role of modified nucleoside…

Principal investigator: dr hab. Grażyna Bożena Leszczyńska

Politechnika Łódzka

Call: OPUS 22, Panel: ST4

33. Antisense oligonucleotides as tools specifically binding viral G-quadruplexes and their experimental verification

Principal investigator: dr Marta Maria Szabat

Instytut Chemii Bioorganicznej PAN

Call: OPUS 25, Panel: ST4

34. Multitasking polymeric lattices included selected DNA oligonucleotide sequences - synthesis, modifications and physioche…

Principal investigator: dr Ewelina Zabost

Uniwersytet Warszawski, Wydział Chemii

Call: SONATA 3, Panel: ST5

35. High-throughput droplet microfluidics for dissecting cellular interactions.

Principal investigator: dr Tomasz Stanisław Kamiński

Uniwersytet Warszawski, Wydział Biologii

Call: SONATA 17, Panel: ST4

36. New high dimensional NMR spectroscopy experiments for three dimensional structure elucidation of nucleic acids.

Principal investigator: Saurabh Kumar Saxena

Uniwersytet Warszawski, Wydział Chemii

Call: PRELUDIUM 6, Panel: ST4

37. Synthesis and structural studies of oligonucleotides with tRNA anticodon stem-loop sequences containing newly discovered…

Principal investigator: prof. Elżbieta Jadwiga Sochacka

Politechnika Łódzka, Wydział Chemiczny

Call: OPUS 13, Panel: ST5

38. catalytic nucleic acids in of the new generation in the regulation of genetic information

Principal investigator: prof. Jan Barciszewski

Instytut Chemii Bioorganicznej PAN

Call: OPUS 9, Panel: ST5

39. New approaches towards modulating selective and functional activities of antisense oligonucleotides

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 2, Panel: ST5

40. Chemically modified mRNA for studies on cellular processes and therapeutic applications

Principal investigator: prof. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 11, Panel: ST5

41. Development of chemical method for synthesis of biologically active triphosphates using thermolabile protecting groups

Principal investigator: dr hab. Marcin Krzysztof Chmielewski

Instytut Chemii Bioorganicznej PAN

Call: OPUS 4, Panel: ST5

42. Towards understanding the cellular fate of exogenously delivered mRNA

Principal investigator: dr hab. Paweł Jan Sikorski

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: SONATA 14, Panel: NZ1

43. Multifunctional smart nanostructured platforms for light-triggered wound healing polytherapy

Principal investigator: dr hab. Filippo Pierini

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Call: SONATA BIS 10, Panel: ST5

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