Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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High throughput microfluidic system for fast determination of the equilibrium constant for biomolecular complexes: application to RNA-DNA interactions

2020/39/O/ST4/00877

Keywords:

microfluidics fluorescence methods RNA recognition sequence in CRISPR system

Descriptors:

  • ST4_005:
  • ST4_001:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Chemii Fizycznej Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Robert Hołyst 

Number of co-investigators in the project: 2

Call: PRELUDIUM BIS 2 - announced on 2020-09-15

Amount awarded: 541 680 PLN

Project start date (Y-m-d): 2021-10-01

Project end date (Y-m-d): 2025-09-30

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Ion Complexation Explains Orders of Magnitude Changes in the Equilibrium Constant of Biochemical Reactions in Buffers Crowded by Nonionic Compounds
    Authors:
    Krzysztof Bielec, Adam Kowalski, Grzegorz Bubak, Emilia Witkowska Nery, and Robert Hołyst
    Academic press:
    The Journal of Physical Chemistry Letters (rok: 2022, tom: 13, strony: 112–117), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.jpclett.1c03596 - link to the publication
  2. Ion Complexation Explains Orders of Magnitude Changes in the Equilibrium Constant of Biochemical Reactions in Buffers Crowded by Nonionic Compounds
    Authors:
    Krzysztof Bielec, Adam Kowalski, Grzegorz Bubak, Emilia Witkowska Nery, and Robert Hołyst
    Academic press:
    The Journal of Physical Chemistry Letters (rok: 2022, tom: 13, strony: 112–117), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.jpclett.1c03596 - link to the publication
  3. Effective screening of Coulomb repulsions in water accelerates reactions of like-charged compounds by orders of magnitude
    Authors:
    Adam Kowalski, Krzysztof Bielec, Grzegorz Bubak, Pawel J. Żuk, Maciej Czajkowski, Volodymyr Sashuk, Wilhelm T. S. Huck, Jan M. Antosiewicz & Robert Holyst
    Academic press:
    Nature Communications (rok: 2022, tom: 13, strony: 6451 (1-9)), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41467-022-34182-z - link to the publication
  4. Effective screening of Coulomb repulsions in water accelerates reactions of like-charged compounds by orders of magnitude
    Authors:
    Adam Kowalski, Krzysztof Bielec, Grzegorz Bubak, Pawel J. Żuk, Maciej Czajkowski, Volodymyr Sashuk, Wilhelm T. S. Huck, Jan M. Antosiewicz & Robert Holyst
    Academic press:
    Nature Communications (rok: 2022, tom: 13, strony: 6451 (1-9)), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41467-022-34182-z - link to the publication