Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRNA complexes.
2020/39/D/ST4/03177
Keywords
Descriptors
- ST4_009: Chemia biologiczna
- NZ1_004: Biologia strukturalna
- NZ7_012: Prewencja chorób człowieka
Panel
ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development
Host institution
Instytut Chemii Bioorganicznej PAN
Voivodeship: wielkopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 7
Call
SONATA 16 – announced on 2020-09-15
- Amount awarded
- 1 174 250 PLN
- Project start date
- 2021-09-01
- Project end date
- 2027-08-31
- Project duration
- 72 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (1)
-
Impact of a Single Nucleotide Change or Non-Nucleoside Modifications in G-Rich Region on the Quadruplex–Duplex Hybrid Formation
- Authors:
- Dorota Gudanis, Karolina Zielińska, Daniel Baranowski, Ryszard Kierzek, Piotr Kozłowski, Zofia Gdaniec
- Academic press:
- Biomolecules (year: 2021, volume: 11, pages: 1236), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/biom11081236 – link to the publication