Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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P-Stereodefined phosphorothioate analogs of DNA containing within nucleobases modifications preventing Watson-Crick base pairings - Hoogsteen interactions with RNA and DNA templates.

2013/11/B/ST5/01581

Keywords:

phosphorothioate analogs of DNA parallel duplex

Descriptors:

  • ST5_16:
  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Maciaszek 

Number of co-investigators in the project: 3

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 250 296 PLN

Project start date (Y-m-d): 2014-08-22

Project end date (Y-m-d): 2017-08-21

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. pompa próżniowa olejowa (10 000 PLN)
  2. Chłodziarko-zamrażarka.
  3. chłodziarko- zamrażarka (1 500 PLN)
  4. Pompa próżniowa membranowa (15 000 PLN)
  5. wyparka rotacyjna (12 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  1. Homopurine Rp-stereodefined phosphorothioate analogs of DNA with hampered Watson-Crick base pairings form Hoogsteen paired parallel duplexes with (2'-OMe)-RNAs
    Authors:
    Anna Maciaszek, Katarzyna Jastrzębska, Piotr Guga
    Academic press:
    Organic & Biomolecular Chemistry (rok: 2019, tom: 17, strony: 4611-4620), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C8OB03112F - link to the publication