Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Stereodefined phosphorothioate analogs of DNA with incorporated LNA-type nucleosides - synthesis and properties of complexes formed with DNA and RNA matrices.

2011/03/B/ST5/02671

Keywords:

PS-DNA LNA triplexes RNA/DNA/RNA

Descriptors:

  • ST5_16:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Centrum Badań Molekularnych i Makromolekularnych PAN

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Piotr Guga 

Number of co-investigators in the project: 7

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 439 540 PLN

Project start date (Y-m-d): 2012-08-29

Project end date (Y-m-d): 2015-08-28

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Opłata licencji na dostęp do bazy SciFinder (5 000 PLN)
  2. Wirówka (35 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  1. Thermal stability and conformation of antiparallel duplexes formed by P-stereodefined phosphorothioate DNA/LNA chimeric oligomers with DNA and RNA matrices.
    Authors:
    Katarzyna Jastrzębska, Anna Maciaszek, Rafał Dolot, Grzegorz Bujacz, Piotr Guga
    Academic press:
    Org. Biomol. Chem ( Organic & Biomolecular Chemistry) (rok: 2015, tom: 13, strony: 10032-100040), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c5ob01474c - link to the publication