Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Tecto-RNA nano-structures for gene expression regulation in a model system

2015/19/B/ST5/03087

Keywords:

RNA RNAi siRNA gene expresion regulation tecto-RNA

Descriptors:

  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • ST5_16:
  • NZ3_14: Other related subjects

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Arkadiusz Chworoś 

Number of co-investigators in the project: 3

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 668 500 PLN

Project start date (Y-m-d): 2016-07-14

Project end date (Y-m-d): 2020-07-13

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. licznik komórek (12 800 PLN)
  2. Mikroskop fluorescencyjny (34 000 PLN)
  3. Thermomixer Comfort.
  4. Stanowisko komputerowe wraz z oprogramowaniem (10 515 PLN)
  5. bioanalizator (124 000 PLN)
  6. termocykler (36 500 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Designing synthetic RNA for delivery by nanoparticles
    Authors:
    Dominika Jedrzejczyk, Edyta Gendaszewska-Darmach, Roza Pawlowska and Arkadiusz Chworos
    Academic press:
    J. Phys.: Condens. Matter (rok: 2017, tom: 29, strony: 123001), Wydawca: IOP
    Status:
    Published
    DOI:
    10.1088/1361-648X/aa5561 - link to the publication
  2. Gold Nanoparticles in Conjunction with Nucleic Acids as a Modern Molecular System for Cellular Delivery
    Authors:
    Anna Graczyk, Roza Pawlowska, Dominika Jedrzejczyk and Arkadiusz Chworos
    Academic press:
    Molecules (rok: 2020, tom: 25, strony: 45318), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25010204 - link to the publication
  3. Highly Fluorescent Distyrylnaphthalene Derivatives as a Tool for Visualization of Cellular Membranes
    Authors:
    Justyna Suwara, Beata Lukasik, Remigiusz Zurawinski, Roza Pawlowska and Arkadiusz Chworos
    Academic press:
    Materials (rok: 2020, tom: 13, strony: 45311), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13040951 - link to the publication
  4. Self-Assembling RNA Nanoparticle for Gene Expression Regulation in a Model System
    Authors:
    Dominika Jedrzejczyk, Arkadiusz Chworos
    Academic press:
    ACS Synth. Biol. (rok: 2019, tom: 8, strony: 491-497), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acssynbio.8b00319 - link to the publication
  5. Gold nanoparticles as carriers for functional RNA nanostructures
    Authors:
    Anna Graczyk, Roza Pawlowska, Arkadiusz Chworos
    Academic press:
    Bioconjugate Chemistry , Wydawca: American Chemical Society
    Status:
    Submitted
    DOI:
    brak - link to the publication

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