Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Chromatographic determination of nucleic acids (DNA, RNA) and their constituents (nucleosides, nucleotides, oligonuceotides) for the genomics with the use of new generation stationary phases

2011/01/D/ST4/04142

Keywords:

nucleic acids high performance liquid chromatography specific stationary phases

Descriptors:

  • ST4_6: Instrumental methods in chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

UNIWERSYTET MIKOŁAJA KOPERNIKA, Wydział Chemii, Katedra Chemii Środowiska i Bioanalityki

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Sylwia Studzińska 

Number of co-investigators in the project: 5

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 396 700 PLN

Project start date (Y-m-d): 2011-12-01

Project end date (Y-m-d): 2014-11-30

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. ŁAZNIA WODNA 2-6 LITRÓW DO 100°C, seria VWB, producent VWR (2 425 PLN)
  2. Mikrowaga MYA 2.3Y/Radwag (30 000 PLN)
  3. Suszarka UFB 400 +30...+220°C, 53 Ltr. wymuszony obieg powietrza, Memmert (6 000 PLN)
  4. Łaźnia ultradźwiękowa z grzaniem DT255H, 5,5 litra i kosz do łaźni "255" (6 000 PLN)
  5. Lodówka (2 000 PLN)
  6. Pompa laboratoryjna próżniowa (3 000 PLN)
  7. Ręczny, cyfrowy tester pH z wymienną elektrodą, ROTH (258 PLN)

Information in the final report

  • Publication in academic press/journals (15)
  1. A new alkyl-phosphate stationary bonded phases for liquid chromatographic separation of biologically active compounds
    Authors:
    Sz. Bocian, A. Nowaczyk, B. Buszewski
    Academic press:
    Analytical Bioanalytical Chemistry (rok: 2012, tom: 404, strony: 731-740), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00216-012-6134-0 - link to the publication
  2. Analysis of normal and modified nucleosides in urine samples by high-erformance liquid chromatography with different stationary phases
    Authors:
    S. Studzińska, B. Buszewski
    Academic press:
    Biomedical Chromatography (rok: 2014, tom: 28, strony: 1140-1146), Wydawca: John Wiley & Sons
    Status:
    Published
    DOI:
    10.1002/bmc.3135 - link to the publication
  3. Fast method for the resolution and determination of sex steroids in urine
    Authors:
    Sylwia Studzińska, Bogusław Buszewski
    Academic press:
    Journal of Chromatography B (rok: 2013, tom: 927, strony: 158-163), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jchromb.2012.12.037 - link to the publication
  4. Dendrimer modified silica gel for anion- exchange chromatography: synthesis, characterization and application
    Authors:
    M. Jaćkowska, Sz. Bocian, B. Buszewski
    Academic press:
    Analyst (rok: 2012, tom: 137, strony: 4610–4617), Wydawca: RSC Publishing
    Status:
    Published
    DOI:
    10.1039/c2an35312a - link to the publication
  5. Determination of nucleotides in infant milk formulas using novel dendrimer ion-exchangers
    Authors:
    S. Studzińska, R. Rola, B. Buszewski
    Academic press:
    Journal of Chromatography B (rok: 2014, tom: 949-950, strony: 87-93), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jchromb.2014.01.012 - link to the publication
  6. Study of hydration process on silica hydride surfaces by microcalorimetry and water adsorption
    Authors:
    Sz. Bocian, G. Rychlicki, M. Matyska, J. Pesek, B. Buszewski
    Academic press:
    Journal of Colloid and Interface Science (rok: 2014, tom: 416, strony: 161-166), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.042 - link to the publication
  7. Hydrophilic interaction liquid chromatography columns classification by effect of solvation and chemometric methods
    Authors:
    Sylwia Noga, Szymon Bocian, Bogusław Buszewski
    Academic press:
    Journal of Chromatography A (rok: 2013, tom: 1278, strony: 89-97), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2012.12.077 - link to the publication
  8. New approach to the determination phosphorothioate oligonucleotides by ultra high performance liquid chromatography coupled with inductively coupled plasma mass spectrometry
    Authors:
    S. Studzińska, S. Mounicou, J. Szpunar, R. Łobiński, B. Buszewski
    Academic press:
    Analytica Chimica Acta (rok: 2014, tom: 855, strony: 13-20), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.aca.2014.12.010 - link to the publication
  9. A new way to fast and high resolution determination of modified nucleosides
    Authors:
    S. Studzińska, B. Buszewski
    Academic press:
    Journal of Chromatography B (rok: 2012, tom: 887, strony: 93-101), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jchromb.2012.01.017 - link to the publication
  10. Comparison of four cholesterol-based stationary phases for the separation of steroid hormones
    Authors:
    J. Soukup, Sz. Bocian, P. Jandera, B. Buszewski
    Academic press:
    Journal of Separation Science (rok: 2014, tom: 37, strony: 345–351), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/jssc.201301088 - link to the publication
  11. 2. Residual silanols at reversed phase silica in HPLC – a contribution for a better understanding
    Authors:
    Sz. Bocian, B. Buszewski
    Academic press:
    Journal of Separation Science (rok: 2012, tom: 35, strony: 1191–1200), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/jssc.201200055 - link to the publication
  12. Application of the zeta potential for stationary phase characterization in ion chromatography
    Authors:
    Bogusław Buszewski, Magdalena Jaćkowska, Szymon Bocian, Ewelina Dziubakiewicz
    Academic press:
    Journal of Separation Science (rok: 2013, tom: 36, strony: 156-163), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/jssc.201200654 - link to the publication
  13. Characterization of new N,O-dialkyl phosphoramidatebonded stationary phases for reversed-phase HPLC – retention and selectivity
    Authors:
    Szymon Bocian, Magdalena Paca, Boguslaw Buszewski
    Academic press:
    Analyst (rok: 2013, tom: 138, strony: 5221-5529), Wydawca: RSC Publishing
    Status:
    Published
    DOI:
    10.1039/c3an00371j - link to the publication
  14. Evaluation of ultra high performance liquid chromatography columns for the analysis of unmodified and antisense oligonucleotides
    Authors:
    S. Studzińska, B. Buszewski
    Academic press:
    Analytical and Bioanalytical Chemistry (rok: 2014, tom: 406, strony: 7127-7136), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00216-014-7959-5 - link to the publication
  15. The Effects of Stationary Phases on Retention and Selectivity of Oligonucleotides in IP-RP-HPLC
    Authors:
    S. Studzińska, L. Pietrzak, B. Buszewski
    Academic press:
    Chromatographia (rok: 2014, tom: 77, strony: 1589-1596), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10337-014-2766-x - link to the publication

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