Search results

51. Oxidation products of 5-methylcytosine as a new predictive markers for respons to systemic chemotherapy of breast cancer…

Principal investigator: dr hab. Marek Foksiński

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny

Call: OPUS 9, Panel: NZ5

52. Amine derivatives of hydantoin as selective 5-HT7 receptor ligand. Molecular modeling, synthesis and pharmacological eva…

Principal investigator: Katarzyna Maria Kucwaj-Brysz

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum Uniwersytet Jagielloński; Wydział Farmaceutyczny

Call: PRELUDIUM 8, Panel: NZ7

53. Non-quinazoline antagonists of apha1 and 5-HT2A receptors with pleiotropic effects as a new perspective for hypertension…

Principal investigator: dr Monika Kubacka

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATA 8, Panel: NZ7

54. Contribution of 5'-end RNA quality control to cellular processes in Arabidopsis thaliana.

Principal investigator: prof. Joanna Kufel

Uniwersytet Warszawski, Wydział Biologii

Call: OPUS 8, Panel: NZ2

55. Unusual 5-HT6 receptor ligands

Principal investigator: prof. Andrzej Jacek Bojarski

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

56. New 5-hydroxymethylcytosine binding proteins

Principal investigator: prof. Matthias Bochtler

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: OPUS 7, Panel: NZ1

57. Studies on ecotoxicity and preliminary evaluation of efficiency of new, variously substituted aminophosphonic systems as…

Principal investigator: dr hab. Jarosław Aleksander Lewkowski

Uniwersytet Łódzki, Wydział Chemii

Call: OPUS 7, Panel: NZ9

58. Synthesis, physicochemical and pharmacological properties of new amide derivatives of 3,3-disubstituted pyrrolidine-2,5-…

Principal investigator: prof. Jolanta Maria Obniska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 6, Panel: NZ7

59. Synthesis, physicochemical and pharmacological studies of new derivatives of 3-substituted pyrrolidine-2,5-dione with an…

Principal investigator: Sabina Joanna Rybka

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 6, Panel: NZ7

60. Synthesis of pyridopyrimidine derivatives, dual affinity ligands for 5-HT1AR and SERT.

Principal investigator: prof. Franciszek Herold

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: OPUS 6, Panel: NZ7

61. Synthesis and biological evaluation of pyrrolidine-2,5-dione derivatives as potential antidepressant agents.

Principal investigator: dr Andrzej Józef Chodkowski

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: OPUS 5, Panel: NZ7

62. Involvement of 5-HT1A receptor signal pathway in the antidepressant effect of zinc

Principal investigator: dr Bernadeta Szewczyk

Instytut Farmakologii PAN

Call: HARMONIA 4, Panel: NZ7

63. A new transition metal complexes incorporating 2,3,5,6-tetra(2-pyridyl)pyrazine ligand in terms of structural, magnetic …

Principal investigator: dr Joanna Wanda Palion-Gazda

UNIWERSYTET ŚLĄSKI, Wydział Matematyki, Fizyki i Chemii

Call: PRELUDIUM 4, Panel: ST5

64. Genetic mechanisms of drug resisntance in breast cancer patients treated with 5-fluorouracil, doxorubicine and cyclophos…

Principal investigator: dr Karolina Halina Tęcza

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie Oddział w Gliwicach

Call: PRELUDIUM 4, Panel: NZ5

65. Members of eIF4E protein family, their affinities towards 5' mRNA cap and protein binding partners: an interdisciplinary…

Principal investigator: prof. Edward Bolesław Darżynkiewicz

Uniwersytet Warszawski, Wydział Fizyki

Call: OPUS 4, Panel: NZ1

66. The examination of isothiocyanates influence on cytotoxic and cytostatic effects of 5-fluorouracil in cancer cell lines …

Principal investigator: Małgorzata Milczarek

Narodowy Instytut Leków

Call: PRELUDIUM 3, Panel: NZ5

67. The study of mechanisms that enhance the antitumor activity of 5-FU by the use of vitamin D analogs in human colon cance…

Principal investigator: dr Magdalena Milczarek

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: PRELUDIUM 3, Panel: NZ5

68. Genome-wide high throughput analysis of 5-hydroxymethylcytosine (5hmC) in Danio rerio (zebra fish)

Principal investigator: Karolina Mierzejewska

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: PRELUDIUM 3, Panel: NZ2

69. The search of new substances with diversified protective properties in different types of animal seizure models among am…

Principal investigator: dr hab. Krzysztof Kamiński

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATA 3, Panel: NZ7

70. Chemical syntesis and evaluation of biochemical properties of 7-methyloguanosine 5'-diphosphate analogs as inhibitors of…

Principal investigator: Marcin Jarosław Ziemniak

Uniwersytet Warszawski, Wydział Fizyki

Call: PRELUDIUM 1, Panel: NZ1

71. In the search for active compounds among ligands of serotonin, particularly 5-HT7, and dopamine receptors, with potentia…

Principal investigator: prof. Anna Małgorzata Wesołowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 1, Panel: NZ4

72. Computationally efficient models for screening of 5-th generation organic light-emitting molecules

Principal investigator: Daria Renata Drwal

Politechnika Łódzka

Call: PRELUDIUM 23, Panel: ST4

73. The early mediaeval settlement complex at Kałdus - Chełmno' sedes regniprincipalis (project 5)

Principal investigator: prof. Wojciech Chudziak

Uniwersytet Mikołaja Kopernika, Wydział Nauk Historycznych

Call: OPUS 23, Panel: HS3

74. Insight into the pollen biology in Arabidopsis thaliana: Functional analysis of annexin 5 (ANN5) in re-organization of t…

Principal investigator: dr Małgorzata Lichocka

Instytut Biochemii i Biofizyki PAN

Call: OPUS 22, Panel: NZ3

75. Search for Inhibitors of Human δ1-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) as Lead Molecules for the Development of N…

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Call: OPUS 22, Panel: NZ7

76. 3D Structure determination of key regulatory regions at the 5' and 3' termini of pathogenic Flaviviruses RNA

Principal investigator: dr Tales Rocha de Moura

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: SONATA 16, Panel: NZ6

77. The effect of methylated resveratrol analogue 3,4,4',5-tetramethoxystilbene (DMU-212) on secretion profile and different…

Principal investigator: Małgorzata Józkowiak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: PRELUDIUM 19, Panel: NZ7

78. Gold and silver nanoparticles as carriers for delivery of 5' end mRNA cap analogues with potential therapeutical applica…

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 16, Panel: ST5

79. Investigation of the influence of electrolyte modification and electrode material with ionic liquids including 2,5-dihyd…

Principal investigator: dr hab. Grzegorz Józef Lota

Politechnika Poznańska, Wydział Technologii Chemicznej

Call: OPUS 16, Panel: ST8

80. Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st…

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: OPUS 16, Panel: NZ2

81. Novel hybrid 5-HT6 serotonin receptor and SERT transporter ligands as a therapeutic perspective of behavioural and cogni…

Principal investigator: dr Agata Siwek

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATA 14, Panel: NZ7

82. Development of a group of non-basic ligands of serotonin receptor 5-HT7, derivatives of 2-(6-oxo-3-phenyl-1,6-dihydropyr…

Principal investigator: dr Sabina Marta Podlewska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATINA 2, Panel: NZ7

83. Comprehensive research on enzymatic hydrolysis of native and chemically modified 5' RNA structures by Nudix protein fami…

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Wydział Fizyki

Call: OPUS 14, Panel: NZ1

84. Application of lithium selenolate as an example of efficient IRC reaction catalyst - synthesis of substituted 5-7 member…

Principal investigator: dr Szymon Buda

Uniwersytet Jagielloński, Wydział Chemii

Call: OPUS 14, Panel: ST5

85. Expression regulation of protein-coding genes overlapping at their 5' ends.

Principal investigator: prof. Izabela Alina Makałowska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: OPUS 13, Panel: NZ2

86. Studies on the rearrangement of vinyl ethers and alkoxydienes in the synthesis of 4-, 5-, and 6-membered carbocyclic com…

Principal investigator: Anna Maria Domżalska-Pieczykolan

Instytut Chemii Organicznej Polska Akademia Nauk

Call: PRELUDIUM 13, Panel: ST5

87. Function of Hsp90 chaperone in the replication of human adenovirus 5

Principal investigator: dr hab. Paweł Bieganowski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 12, Panel: NZ6

88. Effectiveness of anticancer activity of DMU-214 (3'-hydroxy-3,4,5,4'-tetrametoxystilbene) in personalized treatment for …

Principal investigator: dr hab. Hanna Helena Piotrowska-Kempisty

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: SONATA 12, Panel: NZ7

89. Determination of the influence of 5' end of RNA modifications and nucleotide or amino acid sequence on the electrostatic…

Principal investigator: Urszula Anna Budniak

Uniwersytet Warszawski, Wydział Chemii

Call: PRELUDIUM 11, Panel: ST4

90. Modulation mitochondrial metabolism and dynamics and tageting DNA methylation of adipose derived mesenchymal stromal ste…

Principal investigator: prof. Krzysztof Marycz

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biologii i Hodowli Zwierząt

Call: OPUS 11, Panel: NZ7

91. The role of protein factors that bind to the 5' non-coding region of human p53 mRNA in regulation of p53 expression at t…

Principal investigator: prof. Jerzy Henryk Ciesiołka

Instytut Chemii Bioorganicznej PAN

Call: OPUS 11, Panel: NZ1

92. The determination of ADME-Tox in vitro for potential CNS-drug candidates acting as potent and selective ligands of serot…

Principal investigator: Annamaria Teresa Lubelska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 11, Panel: NZ7

93. MicroRNAs expression of human peripheral blood monocytes following in vitro exposure to ambient fine particulate matter …

Principal investigator: dr hab. Ewa Konduracka

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Call: OPUS 11, Panel: NZ7

94. The influence of a new hybryd compound derived from 2-(2,5-dioxopyrrolidin-1-yl) propanamide on hippocampal neuroprotect…

Principal investigator: dr hab. Marta Andres-Mach

Instytut Medycyny Wsi im. Witolda Chodźki

Call: OPUS 10, Panel: NZ7

95. Novel 5 level cascaded converter with predictive controller powered from a single dc source.

Principal investigator: Paweł Wiatr

Instytut Elektrotechniki

Call: PRELUDIUM 8, Panel: ST7

96. New methods for precise control of robotic astronomical 0,5-m telescope mount

Principal investigator: prof. Krzysztof Roman Kozłowski

Politechnika Poznańska, Wydział Informatyki

Call: OPUS 8, Panel: ST7

97. The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal r…

Principal investigator: prof. Grzegorz Władysław Hess

Instytut Farmakologii PAN

Call: OPUS 6, Panel: NZ4

98. Influence of gonadotropic hormones and growth hormone on the regulation of expression of aquaporin 1, 5 and 9 in the cel…

Principal investigator: dr hab. Mariusz Tomasz Skowroński

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

Call: OPUS 5, Panel: NZ9

99. The role of the 5' non-coding regions of p53 mRNA transcripts, which are synthesized from various transcription promoter…

Principal investigator: prof. Jerzy Henryk Ciesiołka

Instytut Chemii Bioorganicznej PAN

Call: OPUS 5, Panel: NZ1

100. New methods for mRNA 5' end labeling and examples of their application in studies on RNA metabolism and searching for in…

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 5, Panel: ST5

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