The study of mechanisms that enhance the antitumor activity of 5-FU by the use of vitamin D analogs in human colon cancer model
2012/05/N/NZ5/00883
Keywords
Descriptors
- NZ5_7: Leczenie chorób człowieka
Panel
NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution
Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk
Voivodeship: dolnośląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 3 – announced on 2012-03-15
- Amount awarded
- 150 000 PLN
- Project start date
- 2013-01-31
- Project end date
- 2016-09-30
- Project duration
- 44 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (1)
-
Vitamin D analogs combined with 5-fluorouracil in human HT-29 colon cancer treatment
- Authors:
- Magdalena Milczarek, Beata Filip-Psurska, Wiesław Świętnicki, Andrzej Kutner, Joanna Wietrzyk
- Academic press:
- ONCOLOGY REPORTS (year: 2014, volume: 32, pages: 491-504), Publisher: Spandidos Publications
- Status:
- Published
- DOI:
- 10.3892/or.2014.3247 – link to the publication
Articles in post-conference publications (2)
-
Vitamin D analogs re-sensitize 5-FU-resistant HT-29 colon cancer cells to this anticancer drug
- Authors:
- M. Milczarek, M. Starostecka, A. Pawlik, A. Anisiewicz, A. Kutner and J. Wietrzyk
- Conference:
- 19th Workshop on Vitamin D (year: 2016, pages: 35), Publisher: Organizers of Vitamin D Workshop
- Date:
- conference 29-31 March 2016
- Status:
- Published
-
Tacalcitol (1,24-dihydroxyvitamin D3) enhances 5-fluorouracil activity by suppressing the thymidylate synthase expression in the colon cancer cells HT-29
- Authors:
- M. Milczarek, D. Kłopotowska, A. Kutner and J. Wietrzyk
- Conference:
- The Tenth Multidisciplinary Conference on Drug Research (year: 2016, pages: 30), Publisher: Pharmaceutical Research Institute
- Date:
- conference 15-19 May 2016
- Status:
- Published