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Function of Hsp90 chaperone in the replication of human adenovirus 5

2016/23/B/NZ6/02536

Keywords:

Adenovirus Hsp90 chaperone

Descriptors:

  • NZ6_5: Virology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Paweł Bieganowski 

Number of co-investigators in the project: 5

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 677 560 PLN

Project start date (Y-m-d): 2017-07-10

Project end date (Y-m-d): 2021-10-09

Project duration:: 51 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Hsp90 and Its Co-Chaperones in Neurodegenerative Diseases
    Authors:
    Bohush A., Bieganowski P., Filipek A.
    Academic press:
    International Journal o f Molecular Sciences (rok: 2019, tom: 20, strony: 45306), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20204976 - link to the publication
  2. Interaction of the middle domains stabilizes Hsp90α dimer in a closed conformation with high affinity for p23.
    Authors:
    Synoradzki K, Miszta P, Kazlauskas E, Mickevičiūtė A, Michailovienė V, Matulis D, Filipek S, Bieganowski P.
    Academic press:
    Biological Chemistry (rok: 2018, tom: 399, strony: 337-345), Wydawca: De Gruyter
    Status:
    Published
    DOI:
    10.1515/hsz-2017-0172 - link to the publication
  3. Heat Shock Protein 90 Chaperones E1A Early Protein of Adenovirus 5 and Is Essential for Replication of the Virus
    Authors:
    Iga Dalidowska, Olga Gazi, Dorota Sulejczak, Maciej Przybylski, Pawel Bieganowski
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 2020), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22042020 - link to the publication

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