Projects funded by the NCN
The effect of methylated resveratrol analogue 3,4,4',5-tetramethoxystilbene (DMU-212) on secretion profile and differentiation ability of human ovarian granulosa cells in 3D model
2020/37/N/NZ7/03465
Keywords:
methylated resveratrol analogues DMU-212 human ovarian granulosa cells mesenchymal cells 3D cell culture model differentiation SIRT-1
Descriptors:
- NZ7_003:
- NZ7_015:
- NZ7_014:
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny
woj. wielkopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 19 - announced on 2020-03-16
Amount awarded: 209 710 PLN
Project start date (Y-m-d): 2021-01-19
Project end date (Y-m-d): 2024-09-18
Project duration:: 44 months (the same as in the proposal)
Project status: Project settled
Project description
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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Steroidogenic activity of liposomal methylated resveratrol analog 3,4,5,4′-tetramethoxystilbene (DMU-212) in human luteinized granulosa cells in a primary three-dimensional in vitro modelAuthors:Małgorzata Józkowiak, Dominik Kobylarek, Artur Bryja, Justyna Gogola-Mruk, Mikołaj Czajkowski, Paulina Skupin-Mrugalska, Bartosz Kempisty, Robert Z. Spaczyński & Hanna Piotrowska-KempistyAcademic press:Endocrine (rok: 2023, tom: 82, strony: 681–694), Wydawca: SpringerStatus:PublishedDOI:10.1007/s12020-023-03458-9 - link to the publication