New 5-hydroxymethylcytosine binding proteins

2014/13/B/NZ1/03991

Keywords

Descriptors

  • NZ1_1: Biologia molekularna
  • NZ1_2: Biochemia
  • NZ1_4: Biologia strukturalna

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Matthias Bochtler

Number of co-investigators in the project: 8

Call

OPUS 7 – announced on 2014-03-17

Amount awarded
1 283 750 PLN
Project start date
2015-01-23
Project end date
2019-01-22
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (8)

  1. On the role of steric clashes in methylation control of restriction endonuclease activity

    Authors:
    Mierzejewska K, Bochtler M, Czapinska H
    Academic press:
    Nucleic Acids Research (year: 2016, volume: 44(1), pages: 485–495), Publisher: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkv1341 – link to the publication
  2. Activity and structure of EcoKMcrA.

    Authors:
    Czapinska H, Kowalska M, Zagorskaite E, Manakova E, Slyvka A, Xu SY, Siksnys V, Sasnauskas G, Bochtler M.
    Academic press:
    Nucleic Acids Research (year: 2018, volume: 46(18), pages: 9829-9841), Publisher: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gky731 – link to the publication
  3. The Bacteroidetes Q-Rule: Pyroglutamate in Signal Peptidase I Substrates.

    Authors:
    Bochtler M, Mizgalska D, Veillard F, Nowak ML, Houston J, Veith P, Reynolds EC, Potempa J.
    Academic press:
    Frontiers in Microbiology (year: 2018, volume: 0,534722222222222, pages: 46035), Publisher: Washington State University
    Status:
    Published
    DOI:
    10.3389/fmicb.2018.00230 – link to the publication
  4. The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers

    Authors:
    Anna Piasecka, Honorata Czapinska, Marie-Theres Vielberg, Roman H. Szczepanowski, Reiner Kiefersauer, Simon Reed, Michael Groll and Matthias Bochtler
    Academic press:
    Journal of Molecular Biology (year: 2018, volume: 430, pages: 611-627), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jmb.2017.11.016 – link to the publication
  5. Crystal structure of the modification-dependent SRA-HNH endonuclease TagI.

    Authors:
    Kisiala M, Copelas A, Czapinska H, Xu SY, Bochtler M.
    Academic press:
    Nucleic Acids Research (year: 2018, volume: 46(19), pages: 10489-10503), Publisher: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gky781 – link to the publication
  6. Nei-like 1 (NEIL1) excises 5-carboxylcytosine directly and stimulates TDG-mediated 5-formyl and 5-carboxylcytosine excision

    Authors:
    Anton Slyvka, Karolina Mierzejewska & Matthias Bochtler
    Academic press:
    Scientific Reports (year: 2017, volume: 7, pages: 46035), Publisher: NATURE PUBLISHING GROUP
    Status:
    Published
    DOI:
    10.1038/s41598-017-07458-4 – link to the publication
  7. Unique mechanism of target recognition by PfoI restriction endonuclease of the CCGG-family.

    Authors:
    Tamulaitiene G, Manakova E, Jovaisaite V, Tamulaitis G, Grazulis S, Bochtler M, Siksnys V.
    Academic press:
    Nucleic Acids Research (year: 2019, volume: 47(2), pages: 997-1010), Publisher: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gky1137 – link to the publication
  8. DNA demethylation pathways: Additional players and regulators.

    Authors:
    Bochtler M, Kolano A, Xu G-L
    Academic press:
    Bioessays (year: 2017, volume: 39(1), pages: 46035), Publisher: WILEY-BLACKWELL
    Status:
    Published
    DOI:
    10.1002/bies.201600178 – link to the publication

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