Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Effectiveness of anticancer activity of DMU-214 (3'-hydroxy-3,4,5,4'-tetrametoxystilbene) in personalized treatment for ovarian cancer

2016/23/D/NZ7/03954

Keywords:

methylated resveratrol analogues DMU-214 CYP1A1 p53 oxygen hypoxia 3D cell culture model mice xenograft model

Descriptors:

  • NZ5_7:
  • NZ7_14:
  • NZ7_15:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Hanna Helena Piotrowska-Kempisty 

Number of co-investigators in the project: 7

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 990 889 PLN

Project start date (Y-m-d): 2017-09-20

Project end date (Y-m-d): 2023-09-19

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Enhanced biological activity of liposomal methylated resveratrol analog 3′-hydroxy-3,4,5,4′-tetramethoxystilbene (DMU-214) in 3D patient-derived ovarian cancer model
    Authors:
    Andrzej Nowicki, Dariusz Wawrzyniak, Mikołaj Czajkowski, Małgorzata Józkowiak, Michał Pawlak, Marcin Wierzchowski, Katarzyna Rolle, Paulina Skupin-Mrugalska, Hanna Piotrowska-Kempisty
    Academic press:
    Drug Delivery (rok: 2022, tom: 29, strony: 2459-2468), Wydawca: taylor & francis
    Status:
    Published
    DOI:
    10.1080/10717544.2022.2103210 - link to the publication