Search results

51. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan…

Principal investigator: prof. Andrzej Mikołaj Pilc

Instytut Farmakologii PAN

Call: OPUS 19, Panel: NZ7

52. Zinc deficient diet as a trigger for treatment-resistant depression in chronically stressed mice. Understanding the mech…

Principal investigator: dr hab. Bernadeta Szewczyk

Instytut Farmakologii PAN

Call: OPUS 19, Panel: NZ5

53. Influence of modified maternal diet on the phenotype of offspring: behavioral and molecular correlations

Principal investigator: Kinga Eryka Gawlińska

Instytut Farmakologii PAN

Call: ETIUDA 8, Panel: NZ7

54. Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system…

Principal investigator: dr Katarzyna Anna Szczepańska

Instytut Farmakologii PAN

Call: SONATINA 4, Panel: NZ7

55. Investigation of novel functionally selective opioid receptors agonists

Principal investigator: Łucja Elżbieta Szumiec

Instytut Farmakologii PAN

Call: ETIUDA 8, Panel: NZ7

56. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor…

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Call: OPUS 18, Panel: NZ7

57. Fluorine substitution – a new algorithm for increasing biological activity

Principal investigator: Wojciech Pietruś

Instytut Farmakologii PAN

Call: PRELUDIUM 18, Panel: NZ7

58. In vivo effects, underlying signaling pathways and mechanism of action of ghrelin receptor agonist against pathological …

Principal investigator: dr Piotr Chmielarz

Instytut Farmakologii PAN

Call: SONATA 15, Panel: NZ7

59. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic …

Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

Instytut Farmakologii PAN

Call: OPUS 18, Panel: NZ7

60. Evaluation of molecular mechanisms of neuroprotective action of dental pulp stromal cells in an ex vivo organotypic mode…

Principal investigator: dr Natalia Helena Bryniarska-Kubiak

Instytut Farmakologii PAN

Call: PRELUDIUM 18, Panel: NZ7

61. Kappa opioid receptors integrate neuronal signaling involved in social behavior

Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

Instytut Farmakologii PAN

Call: OPUS 18, Panel: NZ7

62. Involvement of astrocytes in the neuroprotective mechanism evoked by enhancement of noradrenergic transmission in trasng…

Principal investigator: Justyna Beata Barut

Instytut Farmakologii PAN

Call: PRELUDIUM 18, Panel: NZ7

63. Pharmacological modulation of histamine H3 and H4 receptors - a new perspective in the treatment of neuropathic pain

Principal investigator: dr Katarzyna Popiołek-Barczyk

Instytut Farmakologii PAN

Call: SONATA 15, Panel: NZ7

64. Endocannabinoid regulation of the motivational tone at the mesolimbic system driven by inflammation

Principal investigator: prof. Katarzyna Maria Starowicz-Bubak

Instytut Farmakologii PAN

Call: OPUS 18, Panel: NZ7

65. Effects of a novel nonaddictive opioid on response to stress

Principal investigator: dr Łucja Elżbieta Szumiec

Instytut Farmakologii PAN

Call: PRELUDIUM 17, Panel: NZ7

66. The role of nitric oxide-dependent pathways in the procognitive effects of muscarinic and metabotropic glutamate recepto…

Principal investigator: dr hab. Joanna Monika Wierońska

Instytut Farmakologii PAN

Call: OPUS 17, Panel: NZ7

67. Wpływ wybranych chemokin na właściwości komórek nerwowych i przekaźnictwo synaptyczne w obszarze kompleksu ciała migdało…

Principal investigator: Joanna Ewa Sowa

Instytut Farmakologii PAN

Call: ETIUDA 7, Panel: NZ4

68. Ocena roli wybranych białek neuronalnych i mikroglejowych w patogenezie schizofrenii - badania w modelu zwierzęcym.

Principal investigator: Katarzyna Anna Chamera

Instytut Farmakologii PAN

Call: ETIUDA 7, Panel: NZ4

69. The influence of muscarinic acetylcholine receptors (M1, M4 and M5) and serotonergic 5-HT1A receptor modulation on cogni…

Principal investigator: dr Paulina Agnieszka Cieślik

Instytut Farmakologii PAN

Call: PRELUDIUM 16, Panel: NZ7

70. The role of epigenetic readers from BET family in the emergence and treatment of schizophrenia-like abnormalities in a n…

Principal investigator: prof. Marzena Małgorzata Maćkowiak

Instytut Farmakologii PAN

Call: OPUS 16, Panel: NZ4

71. Rational design and evaluation of functionally biased opioid agonists

Principal investigator: prof. Ryszard Przewłocki

Instytut Farmakologii PAN

Call: OPUS 16, Panel: NZ7

72. Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotec…

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

Call: OPUS 16, Panel: NZ7

73. The effect of chronic treatment with iasenapine and iloperidone on the expression and activity of cytochrome P450 in the…

Principal investigator: dr Przemysław Jan Danek

Instytut Farmakologii PAN

Call: PRELUDIUM 16, Panel: NZ7

74. Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st…

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: OPUS 16, Panel: NZ2

75. The role of cognitive bias in individual vulnerability to to the transition from controlled use to uncontrolled abuse of…

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Call: OPUS 16, Panel: NZ7

76. Modified maternal diet as a factor of autism spectrum disorders in offspring - preclinical molecular studies on prefront…

Principal investigator: Kinga Eryka Gawlińska

Instytut Farmakologii PAN

Call: PRELUDIUM 15, Panel: NZ7

77. New strategies in neuropathic pain pharmacotherapy based on the modulation of the functions of chemokine receptors CCR2 …

Principal investigator: dr Klaudia Kwiatkowski

Instytut Farmakologii PAN

Call: PRELUDIUM 15, Panel: NZ7

78. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

Principal investigator: prof. Barbara Elżbieta Przewłocka

Instytut Farmakologii PAN

Call: OPUS 15, Panel: NZ7

79. The role of selected metabotropic glutamate receptors in the mechanism of rapid antidepressant effect of RS-ketamine and…

Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

Instytut Farmakologii PAN

Call: OPUS 14, Panel: NZ7

80. How microglia-astrocyte interaction affects neuronal functioning in the dopaminergic system. Analysis of the protective …

Principal investigator: dr Katarzyna Zofia Kuter

Instytut Farmakologii PAN

Call: OPUS 14, Panel: NZ7

81. The influence of perinatal exposure to selective serotonin reuptake inhibitors on the structure and functions of mice do…

Principal investigator: prof. Grzegorz Władysław Hess

Instytut Farmakologii PAN

Call: OPUS 14, Panel: NZ4

82. Modulation of inflammatory processes using new agonists of the formyl peptide receptors ALX/FPR2 as a new therapeutic st…

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Call: HARMONIA 9, Panel: NZ7

83. Development of unique molecular probes: low-basicity agonists for the study of 5-HT7 receptor function

Principal investigator: prof. Andrzej Jacek Bojarski

Instytut Farmakologii PAN

Call: OPUS 13, Panel: NZ7

84. The role of endoplasmic reticulum stress in the pathomechanisms of early-life stress-induced dysfunction of the prefrona…

Principal investigator: dr hab. Agnieszka Chocyk

Instytut Farmakologii PAN

Call: OPUS 13, Panel: NZ7

85. Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p…

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Call: OPUS 13, Panel: NZ7

86. Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

Principal investigator: dr Anna Maria Rafało-Ulińska

Instytut Farmakologii PAN

Call: PRELUDIUM 13, Panel: NZ5

87. The effects of thyroid hormones in the brain in an animal model of depression

Principal investigator: prof. Bogusława Budziszewska

Instytut Farmakologii PAN

Call: OPUS 13, Panel: NZ7

88. Comparative effects of 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) and olanzapine on the cognitive dysfunction meas…

Principal investigator: dr hab. Agnieszka Wąsik

Instytut Farmakologii PAN

Call: OPUS 13, Panel: NZ7

89. Evaluation of the influence of progressive noradrenergic neurodegeneration on dopaminergic system functioning in context…

Principal investigator: dr Grzegorz Kreiner

Instytut Farmakologii PAN

Call: OPUS 13, Panel: NZ7

90. Regulation of alternative Dclk1 kinase gene isoforms by psychotropic drugs

Principal investigator: Magdalena Agata Zygmunt

Instytut Farmakologii PAN

Call: PRELUDIUM 12, Panel: NZ3

91. Role of oxidative stress and ceramide in the pathogenesis of depression and in the mechanizm of action of antidepressant…

Principal investigator: Justyna Józefa Brodowicz

Instytut Farmakologii PAN

Call: PRELUDIUM 12, Panel: NZ5

92. Evaluation of interactions of aripiprazole, the atypical amtipsychotic drug, with the selected antidepressants in the ra…

Principal investigator: dr hab. Zofia Maria Rogóż

Instytut Farmakologii PAN

Call: OPUS 12, Panel: NZ7

93. The role of brain glutamatergic system in the neuroendocrine regulation of cytochrome P450 expression and activity in th…

Principal investigator: prof. Władysława Anna Daniel

Instytut Farmakologii PAN

Call: OPUS 12, Panel: NZ7

94. Sensitivity to negative feedback as a cognitive biomarker of depression in an animal model

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Call: OPUS 12, Panel: NZ4

95. The role of synovial fibroblasts' activity in joint pain in osteoarthritis

Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

Instytut Farmakologii PAN

Call: OPUS 12, Panel: NZ7

96. Molecular characteristics of stress-resilient phenotype using mice models.

Principal investigator: prof. Marta Dziedzicka-Wasylewska

Instytut Farmakologii PAN

Call: OPUS 12, Panel: NZ4

97. Impact of early-life stress on maturation, permeability of blood brain-barrier and neuroinflammatory processes activatio…

Principal investigator: Anna Katarzyna Solarz

Instytut Farmakologii PAN

Call: PRELUDIUM 12, Panel: NZ4

98. The evaluation of the efficacy of alpha7 nicotinic acetylcholine receptor ligands in rat models of autism

Principal investigator: dr hab. Agnieszka Anna Nikiforuk

Instytut Farmakologii PAN

Call: OPUS 12, Panel: NZ7

99. The role of codependent 5-HT1a and 5-HT7 receptor signalling in the hippocampal stress response

Principal investigator: Marcin Siwiec

Instytut Farmakologii PAN

Call: PRELUDIUM 12, Panel: NZ4

100. Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte…

Principal investigator: Anna Piotrowska-Murzyn

Instytut Farmakologii PAN

Call: PRELUDIUM 12, Panel: NZ7

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