Projects funded by the NCN
The role of epigenetic readers from BET family in the emergence and treatment of schizophrenia-like abnormalities in a neurodevelopmental model of schizophrenia.
2018/31/B/NZ4/01465
Keywords:
schizophrenia neurodevelopment epigenetics therapy
Descriptors:
- NZ4_9: Systems neurobiology
- NZ7_14: Pharmacy, pharmacotherapy, pharmacology
- NZ4_7: Neurophysiology
Panel:
NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution :
Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 5
Call: OPUS 16 - announced on 2018-09-14
Amount awarded: 1 607 690 PLN
Project start date (Y-m-d): 2019-07-08
Project end date (Y-m-d): 2024-07-07
Project duration:: 36 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Epigenetic targets in schizophrenia development and therapyAuthors:Agnieszka Wawrzczak-Bargieła, Wiktor Bilecki, Marzena MaćkowiakAcademic press:Brain Sciences (rok: 2023, tom: 13, strony: 426), Wydawca: MDPIStatus:PublishedDOI:10.3390/brainsci13030426 - link to the publication
- Inhibition of BET proteins during adolescence affects prefrontal cortical development: Relevance to schizophreniaAuthors:Wiktor Bilecki, Agnieszka Wawrzczak-Bargieła, Iwona Majcher-Maślanka, Magdalena Chmelova, Marzena MaćkowiakAcademic press:International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 8710), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms22168710 - link to the publication