Evaluation of molecular mechanisms of neuroprotective action of dental pulp stromal cells in an ex vivo organotypic model of ischemia

2019/35/N/NZ7/04180

Keywords

Descriptors

  • NZ7_014: Farmacja, farmakoterapia, farmakologia
  • NZ7_012: Prewencja chorób człowieka
  • NZ3_006: Neurobiologia komórkowa

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Instytut Farmakologii PAN

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Natalia Helena Bryniarska-Kubiak

Number of co-investigators in the project: 2

Call

PRELUDIUM 18 – announced on 2019-09-16

Amount awarded
209 544 PLN
Project start date
2020-06-18
Project end date
2025-06-17
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (4)

  1. The emerging role of mechanical and topographical factors in the development and treatment of nervous system disorders: dark and light sides of the force

    Authors:
    Natalia Bryniarska-Kubiak, Andrzej Kubiak, Małgorzata Lekka, Agnieszka Basta-Kaim
    Academic press:
    Pharmacological Reports (year: 2021, volume: 73(6), pages: 1626–1641), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s43440-021-00315-2 – link to the publication
  2. Oxygen-Glucose Deprivation in Organotypic Hippocampal Cultures Leads to Cytoskeleton Rearrangement and Immune Activation: Link to the Potential Pathomechanism of Ischaemic Stroke

    Authors:
    Bryniarska-Kubiak N, Kubiak A, Trojan E, Wesołowska J, Lekka M, Basta-Kaim A.
    Academic press:
    Cells (year: 2023, volume: 12(11):1465, pages: 12(11):1465), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cells12111465 – link to the publication
  3. Mechanotransductive receptor Piezo1 as a promising target in the treatment of neurological diseases

    Authors:
    Bryniarska-Kubiak N, Kubiak A, Basta-Kaim A
    Academic press:
    Current Neuropharmacology (year: 2022, volume: na ten moment brak numeracji tomu, pages: na ten moment brak numeracji stron), Publisher: Bentham Science
    Status:
    Published
    DOI:
    10.2174/1570159X20666220927103454 – link to the publication
  4. Mechanobiology of Dental Pulp Cells

    Authors:
    Bryniarska-Kubiak N, Basta-Kaim A, Kubiak A.
    Academic press:
    Cells (year: 2024, volume: 13(5):375, pages: 13(5):375), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cells13050375 – link to the publication

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