Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Evaluation of molecular mechanisms of neuroprotective action of dental pulp stromal cells in an ex vivo organotypic model of ischemia

2019/35/N/NZ7/04180

Keywords:

ischemia oxygen-glucose deprivation dental pulp stromal cells paracrine effects chemokines cytokines

Descriptors:

  • NZ7_014:
  • NZ7_012:
  • NZ3_006:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Natalia Helena Bryniarska-Kubiak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 18 - announced on 2019-09-16

Amount awarded: 209 544 PLN

Project start date (Y-m-d): 2020-06-18

Project end date (Y-m-d): 2025-06-17

Project duration:: 60 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Oxygen-Glucose Deprivation in Organotypic Hippocampal Cultures Leads to Cytoskeleton Rearrangement and Immune Activation: Link to the Potential Pathomechanism of Ischaemic Stroke
    Authors:
    Bryniarska-Kubiak N, Kubiak A, Trojan E, Wesołowska J, Lekka M, Basta-Kaim A.
    Academic press:
    Cells (rok: 2023, tom: 12(11):1465, strony: 12(11):1465), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells12111465 - link to the publication
  2. Mechanobiology of Dental Pulp Cells
    Authors:
    Bryniarska-Kubiak N, Basta-Kaim A, Kubiak A.
    Academic press:
    Cells (rok: 2024, tom: 13(5):375, strony: 13(5):375), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells13050375 - link to the publication
  3. Mechanotransductive receptor Piezo1 as a promising target in the treatment of neurological diseases
    Authors:
    Bryniarska-Kubiak N, Kubiak A, Basta-Kaim A
    Academic press:
    Current Neuropharmacology (rok: 2022, tom: na ten moment brak numeracji tomu, strony: na ten moment brak numeracji stron), Wydawca: Bentham Science
    Status:
    Published
    DOI:
    10.2174/1570159X20666220927103454 - link to the publication
  4. The emerging role of mechanical and topographical factors in the development and treatment of nervous system disorders: dark and light sides of the force
    Authors:
    Natalia Bryniarska-Kubiak, Andrzej Kubiak, Małgorzata Lekka, Agnieszka Basta-Kaim
    Academic press:
    Pharmacological Reports (rok: 2021, tom: 73(6), strony: 1626–1641), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s43440-021-00315-2 - link to the publication

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