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Regulation of alternative Dclk1 kinase gene isoforms by psychotropic drugs

2016/23/N/NZ3/00133

Keywords:

Dclk1 splicing neuroplasticity gene expression psychotropic drugs

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ2_2: Genomics, transcriptomics, epigenomics

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Farmakologii Polskiej Akademii Nauk

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Magdalena Zygmunt 

Number of co-investigators in the project: 3

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 99 672 PLN

Project start date (Y-m-d): 2017-08-29

Project end date (Y-m-d): 2019-08-28

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Decoding the transcriptional programs activated by psychotropic drugs in the brain
    Authors:
    Magdalena Zygmunt, Marcin Piechota, Jan Rodriguez Parkitna, Michał Korostyński
    Academic press:
    Genes, Brain and Behavior (rok: 2018, tom: e12511, strony: e12511), Wydawca: Wiley-Blackwell
    Status:
    Published
    DOI:
    10.1111/gbb.12511 - link to the publication
  2. Expression of alternatively spliced variants of the Dclk1 gene is regulated by psychotropic drugs.
    Authors:
    Zygmunt M, Hoinkis D, Hajto J, Piechota M, Skupień-Rabian B, Jankowska U, Kędracka-Krok S, Rodriguez Parkitna J, Korostyński M
    Academic press:
    BMC Neuroscience (rok: 2018, tom: 19(1), strony: 55: 1-14), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12868-018-0458-4 - link to the publication
  1. A novel Dclk1 transcript is selectively induced by drugs acting on serotonin signalling
    Authors:
    M. Zygmunt, D. Hoinkis, J. Hajto, M. Piechota, J. Rodriguez Parkitna, M. Korostyński
    Conference:
    31st ECNP Congress (rok: 2018, ), Wydawca: ELSEVIER SCIENCE BV
    Data:
    konferencja 6-9 październik
    Status:
    Published

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