Ocena roli wybranych białek neuronalnych i mikroglejowych w patogenezie schizofrenii - badania w modelu zwierzęcym.
2019/32/T/NZ4/00308
Descriptors
- NZ4_008: Neuroendokrynologia
- NZ4_009: Neurobiologia systemowa
- NZ3_005: Neurobiologia molekularna
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Instytut Farmakologii PAN
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
ETIUDA 7 – announced on 2018-12-14
- Amount awarded
- 101 632 PLN
- Project start date
- 2019-10-01
- Project end date
- 2020-09-30
- Project duration
- 12 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (4)
-
Shedding light on the role of CX3CR1 in the pathogenesis of schizophrenia
- Authors:
- Katarzyna Chamera, Magdalena Szuster-Głuszczak, Agnieszka Basta-Kaim
- Academic press:
- Pharmacological Reports (year: 2021, volume: 73, pages: 1063-1078), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s43440-021-00269-5 – link to the publication
-
Maternal Immune Activation Sensitizes Male Offspring Rats to Lipopolysaccharide-Induced Microglial Deficits Involving the Dysfunction of CD200-CD200R and CX3CL1-CX3CR1 Systems
- Authors:
- Katarzyna Chamera, Magdalena Szuster-Głuszczak, Ewa Trojan, Agnieszka Basta-Kaim
- Academic press:
- Cells (year: 2020, volume: 9, pages: 46052), Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
- Status:
- Published
- DOI:
- 10.3390/cells9071676 – link to the publication
-
The prenatal challenge with lipopolysaccharide and polyinosinic:polycytidylic acid disrupts CX3CL1-CX3CR1 and CD200-CD200R signalling in the brains of male rat offspring: a link to schizophrenia-like behaviours
- Authors:
- Katarzyna Chamera, Katarzyna Kotarska, Magdalena Szuster-Głuszczak, Ewa Trojan, Alicja Skórkowska, Bartosz Pomierny, Weronika Krzyżanowska, Natalia Bryniarska, Agnieszka Basta-Kaim
- Academic press:
- Journal of Neuroinflammation (year: 2020, volume: 17, pages: 46046), Publisher: BioMed Central (BMC)
- Status:
- Published
- DOI:
- 10.1186/s12974-020-01923-0 – link to the publication
-
Role of Polyinosinic:Polycytidylic Acid-Induced Maternal Immune Activation and Subsequent Immune Challenge in the Behaviour and Microglial Cell Trajectory in Adult Offspring: A Study of the Neurodevelopmental Model of Schizophrenia
- Authors:
- Katarzyna Chamera, Ewa Trojan, Katarzyna Kotarska, Magdalena Szuster-Głuszczak, Natalia Bryniarska, Kinga Tylek, Agnieszka Basta-Kaim
- Academic press:
- International Journal of Molecular Sciences (year: 2021, volume: 22, pages: 46048), Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
- Status:
- Published
- DOI:
- 10.3390/ijms22041558 – link to the publication
Articles in post-conference publications (1)
-
The exposure to the viral component Poly I:C leads to an elevation of CX3CL1 level in cortical organotypic cultures
- Authors:
- Katarzyna Chamera, Magdalena Szuster, Ewa Trojan, Agnieszka Basta-Kaim
- Conference:
- Workshop on Glial Cells-Neuron Crosstalk in CNS Health and Disease (year: 2020, pages: 44), Publisher: Neuroscience Institute Cavalieri Ottolenghi and Department of Neuroscience Rita Levi-Montalcini, University of Turin, Italy
- Date:
- conference 1-3.10.2020
- Status:
- Published