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Ocena roli wybranych białek neuronalnych i mikroglejowych w patogenezie schizofrenii - badania w modelu zwierzęcym.

2019/32/T/NZ4/00308

Keywords:

Descriptors:

  • NZ4_8: Neuroendocrinology
  • NZ4_9: Systems neurobiology
  • NZ3_5: Molecular neurobiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Katarzyna Chamera 

Number of co-investigators in the project: 2

Call: ETIUDA 7 - announced on 2018-12-14

Amount awarded: 101 632 PLN

Project start date (Y-m-d): 2019-10-01

Project end date (Y-m-d): 2020-09-30

Project duration:: 12 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (1)
  1. Maternal Immune Activation Sensitizes Male Offspring Rats to Lipopolysaccharide-Induced Microglial Deficits Involving the Dysfunction of CD200-CD200R and CX3CL1-CX3CR1 Systems
    Authors:
    Katarzyna Chamera, Magdalena Szuster-Głuszczak, Ewa Trojan, Agnieszka Basta-Kaim
    Academic press:
    Cells (rok: 2020, tom: 9, strony: 45321), Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
    Status:
    Published
    DOI:
    10.3390/cells9071676 - link to the publication
  2. Shedding light on the role of CX3CR1 in the pathogenesis of schizophrenia
    Authors:
    Katarzyna Chamera, Magdalena Szuster-Głuszczak, Agnieszka Basta-Kaim
    Academic press:
    Pharmacological Reports (rok: 2021, tom: 73, strony: 1063-1078), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s43440-021-00269-5 - link to the publication
  3. Role of Polyinosinic:Polycytidylic Acid-Induced Maternal Immune Activation and Subsequent Immune Challenge in the Behaviour and Microglial Cell Trajectory in Adult Offspring: A Study of the Neurodevelopmental Model of Schizophrenia
    Authors:
    Katarzyna Chamera, Ewa Trojan, Katarzyna Kotarska, Magdalena Szuster-Głuszczak, Natalia Bryniarska, Kinga Tylek, Agnieszka Basta-Kaim
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 45317), Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
    Status:
    Published
    DOI:
    10.3390/ijms22041558 - link to the publication
  4. The prenatal challenge with lipopolysaccharide and polyinosinic:polycytidylic acid disrupts CX3CL1-CX3CR1 and CD200-CD200R signalling in the brains of male rat offspring: a link to schizophrenia-like behaviours
    Authors:
    Katarzyna Chamera, Katarzyna Kotarska, Magdalena Szuster-Głuszczak, Ewa Trojan, Alicja Skórkowska, Bartosz Pomierny, Weronika Krzyżanowska, Natalia Bryniarska, Agnieszka Basta-Kaim
    Academic press:
    Journal of Neuroinflammation (rok: 2020, tom: 17, strony: 45315), Wydawca: BioMed Central (BMC)
    Status:
    Published
    DOI:
    10.1186/s12974-020-01923-0 - link to the publication
  1. The exposure to the viral component Poly I:C leads to an elevation of CX3CL1 level in cortical organotypic cultures
    Authors:
    Katarzyna Chamera, Magdalena Szuster, Ewa Trojan, Agnieszka Basta-Kaim
    Conference:
    Workshop on Glial Cells-Neuron Crosstalk in CNS Health and Disease (rok: 2020, ), Wydawca: Neuroscience Institute Cavalieri Ottolenghi and Department of Neuroscience Rita Levi-Montalcini, University of Turin, Italy
    Data:
    konferencja 1-3.10.2020
    Status:
    Published

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