Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Sensitivity to negative feedback as a cognitive biomarker of depression in an animal model

2016/23/B/NZ4/01562

Keywords:

depression animal model behaviour rat stress

Descriptors:

  • NZ4_9: Systems neurobiology
  • HS6_1: General psychology (cognitive processes, emotions, motivations, personality, individual differences), experimental psychology, psycholinguistics

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Rafał Ryguła 

Number of co-investigators in the project: 4

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 854 951 PLN

Project start date (Y-m-d): 2017-07-19

Project end date (Y-m-d): 2021-07-18

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. 2 komputery osobiste i drukarka (2 szt.) (2 459 PLN)
  2. Gilotyna do humanitarnego uśmiercania zwierząt laboratoryjnych.
  3. Zestaw do pomiaru lękliwości u zwierząt laboratoryjnych (114 543 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (8)
  1. Phenotypes of reinforcement sensitivity as predictors of the response to acute antidepressant treatment in rats
    Authors:
    Karolina Noworyta, Rafal Rygula
    Academic press:
    European Neuropsychopharmacology (rok: 2021, tom: 43, strony: 102-115), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1016/j.euroneuro.2020.12.004 - link to the publication
  2. Trait Sensitivity to Negative and Positive Feedback Does Not Interact With the Effects of Acute Antidepressant Treatment on Hedonic Status in Rats
    Authors:
    Paulina Surowka, Karolina Noworyta, Rafal Rygula
    Academic press:
    Frontiers in Behavioral Neuroscience (rok: 2020, tom: 14, strony: 147), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnbeh.2020.00147 - link to the publication
  3. Sensitivity to negative and positive feedback as a stable and enduring behavioural trait in rats.
    Authors:
    Noworyta-Sokolowska K, Kozub A, Jablonska J, Rodriguez Parkitna J, Drozd R, Rygula R.
    Academic press:
    Psychopharmacology (rok: 2019, tom: Aug; 236(8), strony: 2389-2403), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00213-019-05333 - link to the publication
  4. Using rodents to model abnormal sensitivity to feedback in depression.
    Authors:
    Rygula R, Noworyta-Sokolowska K, Drozd R, Kozub A.
    Academic press:
    Neuroscience and Biobehavioral Reviews (rok: 2018, tom: Dec;95, strony: 336-346), Wydawca: Elsevier
    Status:
    Published
  1. Sensitivity to negative and positive feedback as stable and enduring behavioural traits in rats
    Authors:
    Karolina Noworyta-Sokołowska, Anna Kozub, Robert Drozd, Rafał Ryguła
    Conference:
    Workshop: Computational Approaches on Animal & Human Behavior Animal and Human Behavior: Using Computational Approaches to Build a Two-way Bridge, - Cambridge, U.K. (rok: 2018, ), Wydawca: EBPS
    Data:
    konferencja 29-31 July 2018
    Status:
    Published
  2. Trait sensitivity to negative feedback determines the effects of chronic stress on motivation in rats
    Authors:
    Paulina Surówka, Karolina Noworyta-Sokołowska, Rafał Ryguła
    Conference:
    Workshop: Cognitive Affective Biases - from mechanisms to disease symptoms (rok: 2019, ), Wydawca: Elsevier
    Data:
    konferencja 43599
    Status:
    Published
  3. Trait sensitivity to negative feedback interacts with the effect of stress on anxiety in rats
    Authors:
    Noworyta K, Surowka P, Rygula R,
    Conference:
    Neuronus IBRO Neuroscience Online Forum (rok: 2020, ), Wydawca: Neuronus
    Data:
    konferencja 8 - 11 Grudnia
    Status:
    Published
  4. Using rodents to model abnormal sensitivity to feedback in depression
    Authors:
    Karolina Noworyta-Sokolowska
    Conference:
    Workshop: Cognitive Affective Biases - from mechanisms to disease symptoms (rok: 2019, ), Wydawca: Elsevier
    Data:
    konferencja 43599
    Status:
    Published
  5. Effects of trait sensitivity to negative feedback on motivation and anxiety of rats following acute administration of antidepressant drugs
    Authors:
    RAFAL RYGULA , KAROLINA NOWORYTA-SOKOLOWSKA , ANNA KOZUB , ROBERT DROZD
    Conference:
    10th IBRO World Congress of Neuroscience, Daegu, Korea (rok: 2019, ), Wydawca: n/a
    Data:
    konferencja 43729
    Status:
    Published
  6. Four phenotypes: a novel animal model linking various levels of reinforcement sensitivity with a putative predisposition to specific mood conditions
    Authors:
    Rygula R, Noworyta K
    Conference:
    International Behavioral Neuroscience Society 30th Meeting (rok: 2021, ), Wydawca: IBNS
    Data:
    konferencja 1 - 5 czerwiec
    Status:
    Published
  7. Phenotypes of reinforcement sensitivity as predictors of the response to acute antidepressant treatment in rats
    Authors:
    Noworyta K, Rygula R
    Conference:
    International Behavioral Neuroscience Society 30th Meeting (rok: 2021, ), Wydawca: IBNS
    Data:
    konferencja 1-5 czerwiec
    Status:
    Published
  8. Phenotypes of reinforcement sensitivity determine motivation and anxiety of rats
    Authors:
    Surówka P, Noworyta-Sokolowska K, Rygula R,
    Conference:
    Neuronus IBRO Neuroscience Online Forum (rok: 2020, ), Wydawca: Neuronus
    Data:
    konferencja 8 - 11 Grudnia
    Status:
    Published