The role of codependent 5-HT1a and 5-HT7 receptor signalling in the hippocampal stress response

2016/23/N/NZ4/03224

Keywords

Descriptors

  • NZ4_7: Neurofizjologia
  • NZ4_9: Neurobiologia systemowa
  • NZ3_6: Neurobiologia komórkowa

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Instytut Farmakologii PAN

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Marcin Siwiec

Number of co-investigators in the project: 2

Call

PRELUDIUM 12 – announced on 2016-09-15

Amount awarded
149 760 PLN
Project start date
2017-07-20
Project end date
2023-07-19
Project duration
72 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. The use of serotonin type 7 receptor antagonists as a pharmacological intervention in chronic stress. Insights from animal studies

    Authors:
    Marcin Siwiec, Grzegorz Hess
    Academic press:
    The International Journal of Biochemistry & Cell Biology (year: 2024, volume: 175, pages: 106647), Publisher: Elsevier
    Status:
    Published
  2. Activation of the 5-HT7 receptor and MMP-9 signaling module in the hippocampal CA1 region is necessary for the development of depressive-like behavior

    Authors:
    Monika Bijata, Ewa Bączyńska, Franziska E Müller, Krystian Bijata, Julia Masternak, Adam Krzystyniak, Bernadeta Szewczyk, Marcin Siwiec, Svitlana Antoniuk, Matylda Roszkowska, Izabela Figiel, Marta Magnowska, Krzysztof H Olszyński, Agnieszka D Wardak, Adam Hogendorf, Błażej Ruszczycki, Nataliya Gorinski, Josephine Labus, Tomasz Stępień, Sylwia Tarka, Andrzej J Bojarski, Krzysztof Tokarski, Robert K Filipkowski, Evgeni Ponimaskin, Jakub Wlodarczyk
    Academic press:
    Cell Reports (year: 2022, volume: 38, pages: 110532), Publisher: Cell Press
    Status:
    Published
    DOI:
    10.1016/j.celrep.2022.110532 – link to the publication
  3. Activation of 5-HT7 receptors in the mouse dentate gyrus does not affect theta-burst-induced plasticity at the perforant path synapse

    Authors:
    Marcin Siwiec, Bartosz Bobula, Michał Kiełbiński, Nikola Multan, Grzegorz Hess, Krzysztof Tokarski
    Status:
    Accepted for publication

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Graphic design and implementation: Jakub Piotrowski