Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The role of synovial fibroblasts' activity in joint pain in osteoarthritis

2016/23/B/NZ7/01143

Keywords:

osteoarthritis biomarkers fibroblasts pain

Descriptors:

  • NZ7_12:
  • NZ7_4:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Katarzyna Maria Starowicz-Bubak 

Number of co-investigators in the project: 5

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 1 649 791 PLN

Project start date (Y-m-d): 2017-08-03

Project end date (Y-m-d): 2021-08-02

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Inflammation‐Driven Secretion Potential Is Upregulated in Osteoarthritic Fibroblast‐Like Synoviocytes
    Authors:
    Chwastek J, Kędziora M, Borczyk M, Korostyński M, Starowicz K.
    Academic press:
    Int. J. Mol. Sci. (rok: 2022, tom: 23, strony: 11817), Wydawca: MDPS
    Status:
    Published
    DOI:
    10.3390/ijms231911817 - link to the publication
  2. Mimicking the Human Articular Joint with In Vitro Model of Neurons-Synoviocytes Co-Culture
    Authors:
    Jakub Chwastek, Marta Kędziora, Małgorzata Borczyk, Michał Korostyński, Katarzyna Starowicz
    Academic press:
    International Journal of Stem Cells (rok: 2023, tom: 45985, strony: 45665), Wydawca: Korean Society for Stem Cell Research
    Status:
    Published
    DOI:
    10.15283/ijsc23043 - link to the publication
  1. DIFFERENTIAL REGULATION OF MATRIX METALLOPROTEINASES BY ANANDAMIDE AND 2-ARACHIDONOYLGLYCEROL IN HUMAN OSTEOARTHRITIC CHONDROCYTES
    Authors:
    MLOST J., STAROWICZ K.
    Conference:
    2018 Osteoarthritis Research Society International (OARSI) World Congress, Liverpool, Wielka Brytania (rok: 2018, ), Wydawca: OARSI
    Data:
    konferencja 26-29.04.2018
    Status:
    Published
  2. The influence of 2-AG on chemokines expression in fibroblast-like synoviocytes stimulated with TNFα.
    Authors:
    CHWASTEK J., BRYK M., STAROWICZ K.
    Conference:
    The 29th Annual ICRS Symposium on the Cannabinoids (rok: 2019, ), Wydawca: International Cannabinoid Research Society
    Data:
    konferencja 29.06.2019-04.07.
    Status:
    Published