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1. Dioscuri Center for Structural Dynamics of Receptors

Principal investigator: Przemysław Nogły

Uniwersytet Jagielloński

Call: DIOSCURI 4, Panel: NZ1

2. New selective antagonists of ionotropic glutamate non-NMDA receptors

Principal investigator: dr Ewa Monika Szymańska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 8, Panel: NZ7

3. New receptors for C-reactive protein recognition - generation, characterization and application towards fast differentia…

Principal investigator: dr Katarzyna Szot-Karpińska

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: SONATA 13, Panel: ST5

4. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan…

Principal investigator: prof. Andrzej Mikołaj Pilc

Instytut Farmakologii PAN

Call: OPUS 19, Panel: NZ7

5. Role of peroxisome proliferator-activated receptors (PPARs) and free fatty acid receptors (FFARs) in androgen-dependent …

Principal investigator: Julia Anna Wajda

Uniwersytet Jagielloński, Wydział Biologii

Call: PRELUDIUM 21, Panel: NZ3

6. Molecular receptors as a tool for studies of interactions agonist/antagonist of H1 - H4 receptors

Principal investigator: Małgorzata Ewa Walczak

Politechnika Łódzka, Wydział Chemiczny

Call: PRELUDIUM 11, Panel: ST5

7. The influence of muscarinic acetylcholine receptors (M1, M4 and M5) and serotonergic 5-HT1A receptor modulation on cogni…

Principal investigator: dr Paulina Agnieszka Cieślik

Instytut Farmakologii PAN

Call: PRELUDIUM 16, Panel: NZ7

8. A clinicopathological analysis of breast cancer with single hormone receptor positive phenotype including a quantitative…

Principal investigator: dr Elżbieta Maria Senkus-Konefka

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: OPUS 13, Panel: NZ5

9. Crosstalk between fibroblast growth factor receptors signaling and regulation of vitamin D receptor in leukemogenesis.

Principal investigator: prof. Ewa Teresa Marcinkowska

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: OPUS 12, Panel: NZ5

10. Crosstalk between vitamin D receptor (VDR) and retinoic acid receptors (RARs) in hematopoiesis.

Principal investigator: prof. Ewa Teresa Marcinkowska

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: OPUS 9, Panel: NZ4

11. Neurotoxic effects of benzophenone-3 : the role of estrogen receptors and retinoid X receptor alpha.

Principal investigator: Agnieszka Wnuk

Instytut Farmakologii PAN

Call: PRELUDIUM 7, Panel: NZ4

12. Structure-activity relationship of bifunctional peptides, agonists of opioid receptors and antagonists of neurokinin rec…

Principal investigator: Jolanta Dyniewicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 2, Panel: ST5

13. Effect of gene polymorphisms of vitamin D receptor (VDR) and the calcium receptor (CASR) in the AD.

Principal investigator: dr Łukasz Łaczmański

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Lekarski Kształcenia Podyplomowego

Call: OPUS 1, Panel: NZ7

14. Positioning the aryl hydrocarbon receptor (AhR) as a new target for pharmacotherapy of sporadic Alzheimer disease: verif…

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

Call: OPUS 28, Panel: NZ7

15. Potential neuroprotective properties of modulators of sphingosine-1-phosphate (S1P) receptors (fingolimod and siponimod)…

Principal investigator: Iga Wieczorek

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 20, Panel: NZ5

16. Relatioship between activation of FGFR-mediated signalling and loss of progesterone receptor in estrogen receptor-positi…

Principal investigator: prof. Radzisław Kordek

Uniwersytet Medyczny w Łodzi, Katedra Onkologii, Zakład Patologii

Call: OPUS 9, Panel: NZ4

17. Novel type modulators of purinergic receptors - Synthesis and study of receptor-ligand interaction

Principal investigator: prof. Zbigniew Jan Leśnikowski

Instytut Biologii Medycznej PAN

Call: OPUS 7, Panel: NZ1

18. Involvement of estrogen receptors, aromatic hydrocarbons receptors and PPAR gamma receptors in the mechanism of endocrin…

Principal investigator: dr hab. Anna Katarzyna Wójtowicz

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

Call: OPUS 4, Panel: NZ4

19. Dual Se-containing 5-HT1A and 5-HT7 biased agonists activating sigma-1 receptor as a hope of finding fast-acting antidep…

Principal investigator: prof. Karolina Anna Pytka

Uniwersytet Jagielloński

Call: OPUS 27, Panel: NZ7

20. Połączone działanie agonistów receptorów adenozynowych i antagonistów receptora P2Y12 zwiększa hamowanie funkcji płytek …

Principal investigator: Nina Małgorzata Wolska

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Call: ETIUDA 7, Panel: NZ3

21. Mechanisms underlying insulin resistance in patients with pulmonary arterial hypertension. The role of peroxisome prolif…

Principal investigator: dr hab. Grzegorz Kopeć

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum

Call: SONATA BIS 7, Panel: NZ5

22. Simultaneous stimulation of muscarinic M4 receptor and selected receptors involved in the regulation of glutamate releas…

Principal investigator: dr hab. Joanna Monika Wierońska

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ7

23. The role of nitric oxide-dependent pathways in the procognitive effects of muscarinic and metabotropic glutamate recepto…

Principal investigator: dr hab. Joanna Monika Wierońska

Instytut Farmakologii PAN

Call: OPUS 17, Panel: NZ7

24. Studies on apoptosis and oxidative damage to biological molecules in tissue-specific and non-specific growth hormone rec…

Principal investigator: dr hab. Adam Gesing

Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

Call: HARMONIA 2, Panel: NZ4

25. Role of Pregnane-X-receptor (PXR) in the pathogenesis of primary sclerosing cholangitis (PSC)

Principal investigator: prof. Piotr Milkiewicz

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

Call: OPUS 1, Panel: NZ5

26. Self-learning systems in the design of compounds modulating GPCR receptors activation.

Principal investigator: dr hab. Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 20, Panel: NZ2

27. Search for new "drug-like" molecules designed as adenosine receptors ligands

Principal investigator: prof. Katarzyna Justyna Kieć-Kononowicz

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: HARMONIA 2, Panel: NZ4

28. Adopted orphan nuclear receptors as new regulators of testis immune privilege

Principal investigator: dr Alicja Kinga Kamińska

Uniwersytet Jagielloński

Call: SONATA 20, Panel: NZ3

29. Structural studies based on low sequence similarity of G protein-coupled receptors activated by hormones and allosteric …

Principal investigator: dr Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Call: SONATA 4, Panel: NZ1

30. Study of ligand binding and activation processes of formyl, opioid and cannabinoid G-protein-coupled receptors

Principal investigator: prof. Sławomir Hubert Filipek

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 2, Panel: NZ1

31. Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st…

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: OPUS 16, Panel: NZ2

32. Participation of transient receptor potential (TRP) channels premeable for calcium ions in memory formation and retrieva…

Principal investigator: dr hab. Elżbieta Jolanta Salińska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 8, Panel: NZ4

33. Impact of selective modulators of estrogen and aryl hydrocarbon receptors on hypoxia/ischemia-induced neuronal cell dama…

Principal investigator: Joanna Rzemieniec

Instytut Farmakologii PAN

Call: PRELUDIUM 1, Panel: NZ3

34. Development of a method for the structure prediction of GPCRs complexes with agonists and antagonists, including the lig…

Principal investigator: dr Michał Koliński

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA 1, Panel: NZ2

35. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic …

Principal investigator: dr Katarzyna Anna Szczepańska

Instytut Farmakologii PAN

Call: OPUS 23, Panel: NZ7

36. Quinoxalino-2,3-diones as potent tools for exploration of ionotropic kainate receptors

Principal investigator: dr hab. Ewa Monika Szymańska

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 20, Panel: NZ7

37. Neurodevelopmental patomechanisms of triclocarban- and dichlorodiphenyldichloroetylene-induced effects: the role of apop…

Principal investigator: dr hab. Małgorzata Kajta

Instytut Farmakologii PAN

Call: OPUS 10, Panel: NZ7

38. Coactivators and corepressors of progesterone receptors as a regulators of progesterone influence on the trissues in the…

Principal investigator: dr Robert Jarosław Rękawiecki

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Call: OPUS 9, Panel: NZ4

39. The mechanism of ligand binding and the conformational changes in the beta2-adrenergic receptor molecule

Principal investigator: dr Anita Płazińska

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

Call: SONATA 5, Panel: NZ2

40. Histamine H3/H4 receptors as the attractive target for the search of biologically active substances

Principal investigator: prof. Katarzyna Justyna Kieć-Kononowicz

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: MAESTRO 1, Panel: NZ4

41. Dual-acting 5-HT6/5-HT7 receptor antagonists: exploring beneficial effects for the treatment of neurodegenerative disord…

Principal investigator: Michał Kamiński

Uniwersytet Jagielloński

Call: PRELUDIUM 24, Panel: NZ7

42. Mechanisms of Antidepressant Action of Psilocybin: The Role of 5-HT2B-5-HT1A Receptor Dimerization and GSK-3β Activation…

Principal investigator: dr hab. Agata Faron-Górecka

Instytut Farmakologii PAN

Call: OPUS 27, Panel: NZ7

43. The role of mineralocorticoid receptor in the regulation of pituitary corticotroph cells secretory activity by glucocort…

Principal investigator: dr hab. Mateusz Bujko

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Call: OPUS 27, Panel: NZ3

44. Yin and Yang effect of P2X and P1 purinergic receptors on compartment of hematopoietic stem cells

Principal investigator: prof. Magdalena Józefa Kucia

Warszawski Uniwersytet Medyczny

Call: OPUS 23, Panel: NZ3

45. Dopaminergic modulation of high frequency oscillations in the rat olfactory bulb associated with the NMDA receptor hypof…

Principal investigator: Jacek Wróbel

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM 20, Panel: NZ4

46. First-in-class dual biased agonists of serotonin 5-HT1A and dopamine D2 receptors – an innovative approach in the search…

Principal investigator: prof. Marcin Roman Kołaczkowski

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 21, Panel: NZ7

47. Increasing the precision of chimeric antigen receptor (CAR)-mediated anticancer immunotherapy by using the chemokine-ind…

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny

Call: OPUS 19, Panel: NZ6

48. Molecular mechanism underlying the anti-inflammatory action of CB2 receptor agonists in microglia: participation of the …

Principal investigator: dr Natalia Eleonora Małek-Chudzik

Politechnika Wrocławska

Call: OPUS 19, Panel: NZ7

49. Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system…

Principal investigator: dr Katarzyna Anna Szczepańska

Instytut Farmakologii PAN

Call: SONATINA 4, Panel: NZ7

50. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor…

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Call: OPUS 18, Panel: NZ7

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