Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Crosstalk between fibroblast growth factor receptors signaling and regulation of vitamin D receptor in leukemogenesis.

2016/23/B/NZ5/00065

Keywords:

leukemia differentiation proliferation fibroblast growth factor receptors vitamin D receptor

Descriptors:

  • NZ5_3:
  • NZ3_1:
  • NZ4_4:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Wrocławski, Wydział Biotechnologii

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Ewa Teresa Marcinkowska 

Number of co-investigators in the project: 5

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 851 500 PLN

Project start date (Y-m-d): 2017-07-17

Project end date (Y-m-d): 2022-07-16

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  • Book publications / chapters in book publications (1)
  1. Regulation of Expression of CEBP Genes by Variably Expressed Vitamin D Receptor and Retinoic Acid Receptor α in Human Acute Myeloid Leukemia Cell Lines
    Authors:
    Marchwicka A, Marcinkowska E.
    Academic press:
    International Journal of Molecular Sciences (rok: 2018, tom: 19, strony: 7), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19071918 - link to the publication
  2. Vitamin D Derivatives in Acute Myeloid Leukemia: The Matter of Selecting the Right Targets
    Authors:
    Ewa Marcinkowska
    Academic press:
    Nutrients (rok: 2022, tom: 14(14), strony: 2851), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu14142851 - link to the publication
  3. Immuno-Stimulating Activity of 1,25-Dihydroxyvitamin D in Blood Cells from Five Healthy People and in Blasts from Five Patients with Leukemias and Pre-Leukemic States
    Authors:
    Aleksandra Marchwicka , Kuba Nowak, Anastasiia Satyr, Dariusz Wołowiec, Ewa Marcinkowska
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: 24(7), strony: 6504), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24076504 - link to the publication
  4. Immuno-Stimulating Activity of 1,25-Dihydroxyvitamin D in Blood Cells from Five Healthy People and in Blasts from Five Patients with Leukemias and Pre-Leukemic States
    Authors:
    Aleksandra Marchwicka , Kuba Nowak, Anastasiia Satyr, Dariusz Wołowiec, Ewa Marcinkowska
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: 24(7), strony: 6504), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24076504 - link to the publication
  5. Overexpressed fibroblast growth factor receptors increase 1,25-dihydroxyvitamin D-dependent differentiation of acute myeloid leukemia cells
    Authors:
    Aleksandra Marchwicka , Urszula Nowak , Anna Grembowska , Agnieszka Jakuszak , Piotr Poręba , Ewa Marcinkowska
    Academic press:
    Journal of Steroid Biochemistry and Molecular Biology (rok: 2022, tom: 224, strony: 106173), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jsbmb.2022.106173 - link to the publication
  1. Experimental Premises for DifferentiationTherapy of Acute Myeloid Leukaemia
    Authors:
    Marcinkowska E, Brown G.
    Book:
    Acute Myeloid Leukaemia (AML) Symptoms, Diagnosis and Treatment (rok: 2018, tom: 1, strony: 79-112), Wydawca: Nova Science Publishers
    Status:
    Published

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