Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Structure-activity relationship of bifunctional peptides, agonists of opioid receptors and antagonists of neurokinin receptors.

2011/03/N/ST5/04725

Keywords:

structure-activity relationship bifunctional peptides opioid receptors neurokinin receptors

Descriptors:

  • ST5_16:
  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Jolanta Dyniewicz 

Number of co-investigators in the project: 3

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 241 200 PLN

Project start date (Y-m-d): 2012-08-27

Project end date (Y-m-d): 2014-12-26

Project duration:: 28 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Kolumna HPLC (2 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (2)
  1. Hydrazone Linker as a Useful Tool for Preparing Chimeric Peptide/Nonpeptide Bifunctional Compounds
    Authors:
    Jolanta Dyniewicz, Piotr F. J. Lipiński, Piotr Kosson, Anna Leśniak, Marta Bochyńska-Czyż, Adriana Muchowska, Dirk Tourwé, Steven Ballet, Aleksandra Misicka, Andrzej W. Lipkowski
    Academic press:
    ACS Medicinal Chemistry Letters (rok: 2016, ), Wydawca: American Chemical Society
    Status:
    Accepted for publication
    DOI:
    10.1021/acsmedchemlett.6b00381 - link to the publication
  1. New Bifunctional Peptides that Hybridize Opioid Agonist with Substance P Antagonist
    Authors:
    Jolanta Dyniewicz, Anna Leśniak, Marta Bochyńska- Czyż, Barbara Nowicka, Andrzej W. Lipkowski
    Conference:
    22nd Polish Peptide Symposium (rok: 2013, ), Wydawca: Oficyna Wydawnicza Politechniki Wrocławskiej
    Data:
    konferencja 1-5 września
    Status:
    Published
    DOI:
    link to the publication
  2. New analgesics with adjuvant anticancer properties.
    Authors:
    Jolanta Dyniewicz, Anna Leśniak, Marta Bochyńska-Czyż, Barbara Nowicka, Piotr Kosson, Steven Ballet, Andrzej W. Lipkowski
    Conference:
    The Ninth Multidisciplinary Conference on Drug Research. Book of Abstracts. (rok: 2014, ), Wydawca: Pielaszek Research
    Data:
    konferencja 12-14.05
    Status:
    Published
    DOI:
    link to the publication

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