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A clinicopathological analysis of breast cancer with single hormone receptor positive phenotype including a quantitative evaluation of estrogen and progesterone receptor expression and microRNA expression profile.

2017/25/B/NZ5/00656

Keywords

Descriptors

  • NZ5_3: Patogeneza chorób człowieka
  • NZ5_5: Diagnostyka chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Gdański Uniwersytet Medyczny, Wydział Lekarski

Voivodeship: pomorskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Elżbieta Maria Senkus-Konefka

Number of co-investigators in the project: 11

Call

OPUS 13 – announced on 2017-03-15

Amount awarded
661 860 PLN
Project start date
2018-02-07
Project end date
2022-08-06
Project duration
54 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zestaw komputerowy (jednostka centralna, monitor, drukarka). Cost: 5 400 PLN

Information in the final report

Publication in academic press/journals (3)

  1. microRNA Expression Profile in Single Hormone Receptor-Positive Breast Cancers Is Mainly Dependent on HER2 Status—A Pilot Study

    Authors:
    Michał Kunc, Marta Popęda, Anna Szałkowska, Magdalena Niemira, Michał Bieńkowski, Rafał Pęksa, Aleksandra Łacko, Barbara S. Radecka, Marcin Braun, Joanna Pikiel, Maria Litwiniuk, Katarzyna Pogoda, Ewa Iżycka-Świeszewska, Adam Krętowski, Anna J. Żaczek, Wojciech Biernat, Elżbieta Senkus-Konefka
    Academic press:
    Diagnostics (year: 2020, volume: 10(9), pages: 617), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/diagnostics10090617 – link to the publication

  2. Lost but Not Least—Novel Insights into Progesterone Receptor Loss in Estrogen Receptor-Positive Breast Cancer

    Authors:
    Michał Kunc, Marta Popęda, Wojciech Biernat, Elżbieta Senkus
    Academic press:
    Cancers (year: 2021, volume: 13(19), pages: 4755), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13194755 – link to the publication

  3. High expression of progesterone receptor may be an adverse prognostic factor in oestrogen receptor-negative/progesterone receptor-positive breast cancer: results of comprehensive re-evaluation of multi-institutional case series

    Authors:
    Michał Kunc, Rafał Pęksa, Gabor Cserni, Ewa Iżycka-Świeszewska, Aleksandra Łacko, Barbara Radecka, Marcin Braun, JoannaPikiel, Maria Litwiniuk, Katarzyna Pogoda, Anna Szwajkosz, Wojciech Biernat, Elżbieta Senkus
    Academic press:
    Pathology (year: 2022, volume: -, pages: 21;S0031-3025(21)00542-0), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pathol.2021.10.003. – link to the publication

Articles in post-conference publications (4)

  1. microRNA expression profiles of single hormone receptor-positive breast cancers

    Authors:
    M. Kunc, M. Popęda, A. Szałkowska, M. Niemira, A. Lacko, B.S. Radecka, M. Braun, J. Pikiel, M. Litwiniuk, K. Pogoda, A. Szwajkosz, E. Izycka-Swieszewska, A.J. Zaczek, W. Biernat, E. Senkus-Konefka
    Conference:
    ESMO Breast Cancer 2020 Congress. (year: 2020, pages: S39), Publisher: Elsevier
    Date:
    conference 23-24 maja 2020
    Status:
    Published

  2. miRNA signatures of prognostic significance in single hormone receptor-positive breast cancer.

    Authors:
    Elzbieta Senkus-Konefka, Marta Popęda, Michał Kunc, Michał Bieńkowski, Marcin Braun, Aleksandra Lacko, Barbara Radecka, Joanna Pikiel, Maria Litwiniuk, Katarzyna Pogoda, Ewa Iżycka-Świeszewska, Anna Joanna Zaczek, Wojciech Biernat
    Conference:
    2022 ASCO Annual Meeting (year: 2022, pages: e12544-e12544), Publisher: American Society of Clinical Oncology
    Date:
    conference 3-7.06.2022
    Status:
    Published

  3. ER-/PgR+ breast cancer is a separate entity characterized by distinct phenotype: Comprehensive reevaluation of cases from Polish and Hungarian centers.

    Authors:
    E. Senkus-Konefka, M. Kunc, R. Pęksa, A. Łacko, B. Radecka, M. Braun, J. Pikiel, M. Litwiniuk, K. Pogoda, A. Szwajkosz, E. Iżycka-Świeszewska, G. Cserni, W. Biernat
    Conference:
    2020 ASCO Annual Meeting (year: 2020, pages: e12554), Publisher: The American Society of Clinical Oncology (ASCO)
    Date:
    conference 29-31 maja 2020
    Status:
    Published

  4. Czy raki piersi o fenotypie ER(-)/PgR(+) naprawdę istnieją? Immunohistochemiczna i histopatologiczna analiza przypadków z dwóch centrów referencyjnych

    Authors:
    Michał Kunc, Rafał Pęksa, Kevin Miszewski, Barbara Radecka, Elżbieta Senkus-Konefka, Wojciech Biernat
    Conference:
    II Konferencja Doktorantów Pomorza BioMed Session 2018, Gdańsk (year: 2018, pages: Książka abstraktów, s. 52), Publisher: Uniwersytet Gdański
    Date:
    conference 7 grudnia 2018
    Status:
    Published

Book publications / chapters in book publications (1)

  1. Analiza kliniczno-patologiczna i ocena profilu ekspresji mikroRNA raków piersi wykazujących ekspresję jednego receptora hormonalnego (ER+/PgR- i ER-/PgR+) : rozprawa doktorska

    Authors:
    Michał Kunc
    Book:
    Analiza kliniczno-patologiczna i ocena profilu ekspresji mikroRNA raków piersi wykazujących ekspresję jednego receptora hormonalnego (ER+/PgR- i ER-/PgR+) : rozprawa doktorska (year: 2022, volume: rozprawa doktorska, pages: rozprawa doktorska), Publisher: Gdański Uniwersytet Medyczny
    Status:
    Published

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