Increasing the precision of chimeric antigen receptor (CAR)-mediated anticancer

Increasing the precision of chimeric antigen receptor (CAR)-mediated anticancer immunotherapy by using the chemokine-induced CAR expression

2020/37/B/NZ6/02191

Keywords

Descriptors

NZ6_008: Inne zagadnienia pokrewne
NZ3_007: Przekaźnictwo sygnału
NZ5_007: Leczenie chorób człowieka

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Warszawski Uniwersytet Medyczny

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Radosław Zagożdżon

Number of co-investigators in the project: 5

Call

OPUS 19 – announced on 2020-03-16

Amount awarded: 2 180 597 PLN
Project start date: 2021-02-01
Project end date: 2025-01-31
Project duration: 48 months (the same as in the proposal)
Project status: Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

3D-Bioprinted Co-Cultures of Glioblastoma Multiforme and Mesenchymal Stromal Cells Indicate a Role for Perivascular Niche Cells in Shaping Glioma Chemokine Microenvironment

Authors:
Zielniok Katarzyna, Rusinek Kinga, Słysz Anna, Lachota Mieszko, Bączyńska Ewa, Wiewiórska-Krata Natalia, Szpakowska Anna, Ciepielak Martyna, Foroncewicz Bartosz, Mucha Krzysztof, Zagożdżon RadosławR, Pojda Z

Academic press:
Cells (year: 2024, volume: 13(17), pages: 1404 (1-25)), Publisher: MDPI

Status:
Published

DOI:
10.3390/cells13171404 – link to the publication
Mapping the chemotactic landscape in NK cells reveals subset-specific synergistic migratory responses to dual chemokine receptor ligation

Authors:
Mieszko Lachota, Katarzyna Zielniok, Daniel Palacios, Minoru Kanaya, Leena Penna, Hanna Julie, Hoel Merete, Thune Wiiger, Lise Kveberg, Wojciech Hautz, Radosław Zagożdżon, Karl-Johan Malmberg

Academic press:
EBioMedicine (year: 2023, volume: 96, pages: 104811), Publisher: Elsevier B.V.

Status:
Published

DOI:
10.1016/j.ebiom.2023.104811 – link to the publication

« New search

Projects search