Projects funded by the NCN
Increasing the precision of chimeric antigen receptor (CAR)-mediated anticancer immunotherapy by using the chemokine-induced CAR expression
2020/37/B/NZ6/02191
Keywords:
anticancer immunotherapy cancer chimeric antigen receptor adoptive therapy chemokine chemokine receptor chemotaxis NK cell NK-92
Descriptors:
- NZ6_008:
- NZ3_007:
- NZ5_007:
Panel:
NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution :
Warszawski Uniwersytet Medyczny
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 5
Call: OPUS 19 - announced on 2020-03-16
Amount awarded: 2 180 597 PLN
Project start date (Y-m-d): 2021-02-01
Project end date (Y-m-d): 2025-01-31
Project duration:: 48 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Mapping the chemotactic landscape in NK cells reveals subset-specific synergistic migratory responses to dual chemokine receptor ligationAuthors:Mieszko Lachota, Katarzyna Zielniok, Daniel Palacios, Minoru Kanaya, Leena Penna, Hanna Julie, Hoel Merete, Thune Wiiger, Lise Kveberg, Wojciech Hautz, Radosław Zagożdżon, Karl-Johan MalmbergAcademic press:EBioMedicine (rok: 2023, tom: 96, strony: 104811), Wydawca: Elsevier B.V.Status:PublishedDOI:10.1016/j.ebiom.2023.104811 - link to the publication