Projects funded by the NCN

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90 projects found matching your search criteria :

  1. Nitroxyl's role in the signaling cross-talk between cell death and life during potato leaves' hypersensitive response to...

    Call: OPUS 28 , Panel: NZ9

    Principal investigator: prof. Magdalena Arasimowicz-Jelonek

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  2. Tick-borne encephalitis virus protease as a molecular target for novel inhibitors and activity-based probes

    Call: OPUS 28 , Panel: NZ6

    Principal investigator: dr Renata Grzywa

    Politechnika Wrocławska

  3. Where Inhibition is not Enough- Development of Innovative Compounds for Targeted Degradation of Extracellular and Membra...

    Call: OPUS 28 (LAP) , Panel: NZ5

    Principal investigator: dr Marcin Skoreński

    Politechnika Wrocławska

  4. The first antibody-drug conjugates for Alzheimer's disease therapy

    Call: SONATA BIS 14 , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  5. Mitochondrial quality control in plants: the relationship between mitophagy and the mitochondrial inner membrane proteas...

    Call: OPUS 27 , Panel: NZ3

    Principal investigator: dr hab. Małgorzata Heidorn-Czarna

    Uniwersytet Wrocławski

  6. Unique metallopeptidase (family M97) in Bacteroidota's species biology and pathogenicity

    Call: OPUS 27 , Panel: NZ1

    Principal investigator: prof. Jan Stanisław Potempa

    Uniwersytet Jagielloński

  7. 'Trojan horse' mechanism used by Candida albicans Sap6 protease in evading neutrophil response

    Call: OPUS 27 , Panel: NZ6

    Principal investigator: dr Marcin Michał Zawrotniak

    Uniwersytet Jagielloński

  8. Polyphosphate condensates in regulation of proteases' localization and activity in stressed Escherichia coli cells

    Call: PRELUDIUM 23 , Panel: NZ1

    Principal investigator: Zuzanna Karolina Hirsz

    Uniwersytet Gdański

  9. Protease-induced neutrophilic networks in cancer development.

    Call: SONATA 19 , Panel: NZ5

    Principal investigator: dr Danuta Teresa Bryzek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  10. Proteolytic processing of adhesion G-protein coupled receptors through proteases

    Call: WEAVE-UNISONO , Panel: NZ1

    Principal investigator: dr Renata Katarzyna Mężyk-Kopeć

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  11. The role of extracytoplasmic proteases in the physiology and morphology of the bacterium Helicobacter pylori

    Call: SONATA 19 , Panel: NZ2

    Principal investigator: dr Urszula Zarzecka

    Uniwersytet Gdański, Wydział Biologii

  12. Macrocyclic peptides for targeting of membrane-anchored serine protease

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Paulina Maria Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  13. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  14. Impact of OMA1 protease on aggregation-prone proteins associated with neurodegenerative diseases.

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Magda Alicja Krakowczyk

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  15. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  16. Biological membranes and macromolecular crowding in the function of the hepatitis C virus proteases

    Call: PRELUDIUM BIS 4 , Panel: NZ1

    Principal investigator: prof. Joanna Dominika Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  17. Role of neutrophil serine proteases in chronic inflammatory skin diseases associated with Regnase-1 malfunction

    Call: OPUS 23 , Panel: NZ6

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  18. The structures, biochemistry, physiology, and evolution of bacterial α2-macroglobulins from the human periodontopathogen...

    Call: SONATA BIS 11 , Panel: NZ1

    Principal investigator: dr Mirosław Książek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  19. Role of DPPIV family proteases in transposon silencing and genome maintenance

    Call: SONATA BIS 11 , Panel: NZ1

    Principal investigator: dr Rajani Kanth Gudipatti

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  20. Hybrid human SUMO proteins for selective detection and labelling of SENP proteases

    Call: OPUS 21 , Panel: ST4

    Principal investigator: dr Wioletta Katarzyna Rut

    Politechnika Wrocławska

  21. The role of neutrophil serine proteases in the regulation of function of the podocyte and glomerular filtration barrier.

    Call: OPUS 21 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  22. Assessment of the functions of granzyme A in neutrophils using induced pluripotent stem cells

    Call: OPUS 20 , Panel: NZ1

    Principal investigator: dr hab. Paulina Maria Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  23. The role of extracellular proteases – yapsins – in gaining pathogenic advantage by Candida glabrata in the host organism...

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Dorota Anna Satała

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  24. Dissecting cancer activome to develop new generation of antibody-drug conjugates

    Call: OPUS 20 (LAP) , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  25. Defining the interplay between SLPI and the IL-1 family cytokines in the immune response

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Ewa Małgorzata Oleszycka

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  26. Neutrophils heterogeneity based on serine proteases

    Call: SONATA BIS 10 , Panel: NZ3

    Principal investigator: dr Paulina Maria Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  27. Role of cereal leaf beetle – associated bacteria in the adaptation of their insect host to the insecticides and protease...

    Call: PRELUDIUM 19 , Panel: NZ9

    Principal investigator: dr Beata Wielkopolan

    Instytut Ochrony Roślin - Państwowy Instytut Badawczy

  28. Molecular mechanism underlying the anti-inflammatory action of CB2 receptor agonists in microglia: participation of the ...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr Natalia Eleonora Małek-Chudzik

    Politechnika Wrocławska

  29. Exploring the allosteric regulation of the SARS CoV-2 hydrolases using methyl-TROSY NMR spectroscopy - in search of nove...

    Call: OPUS 19 , Panel: ST4

    Principal investigator: prof. Wiktor Adam Koźmiński

    Uniwersytet Warszawski, Wydział Chemii

  30. Host sex effect on immunity and protection after oral immunization with Fasciola hepatica cysteine protease and the para...

    Call: OPUS 18 , Panel: NZ6

    Principal investigator: dr hab. Małgorzata Joanna Kęsik-Brodacka

    Narodowy Instytut Leków

  31. Novel analogs of human cathelicidin (LL-37) with enhanced resistant to enzymatic degradation. Design chemical synthesis ...

    Call: PRELUDIUM BIS 1 , Panel: ST4

    Principal investigator: prof. Adam Jerzy Lesner

    Uniwersytet Gdański, Wydział Chemii

  32. The KLIKK proteases of human pathogen Tannerella forsythia: putative virulence factors with unique biochemical and struc...

    Call: OPUS 18 , Panel: NZ1

    Principal investigator: dr Mirosław Książek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  33. SufA bacterial protease inhibitors as potential diagnostic tools and antibacterial agents.

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Ewa Magdalena Burchacka

    Politechnika Wrocławska

  34. Molecular basics of type II transmembrane serine proteases (TTSPs)-mediated activation of influenza viruses

    Call: BEETHOVEN LIFE 1 , Panel: NZ1

    Principal investigator: dr Paweł Zmora

    Instytut Chemii Bioorganicznej PAN

  35. Characterization of two novel proteases from the human periodontopathogen Tannerella forsythia

    Call: PRELUDIUM 16 , Panel: NZ1

    Principal investigator: Irena Maria Waligórska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  36. Dissecting the proteolytic fingerprint of breast cancer tissues using mass cytometry for personalized oncology.

    Call: SONATA 14 , Panel: NZ5

    Principal investigator: dr Marcin Łukasz Poręba

    Politechnika Wrocławska, Wydział Chemiczny

  37. Application of lanthanides in activity-based probes for the simultaneous detection of proteolytic enzymes.

    Call: HARMONIA 10 , Panel: ST5

    Principal investigator: prof. Marcin Drąg

    Politechnika Wrocławska, Wydział Chemiczny

  38. CP protease of the O'nyong-nyong virus: substrate profiling, design and synthesis of inhibitors and activity-based probe...

    Call: OPUS 15 , Panel: NZ6

    Principal investigator: dr hab. Marcin Sieńczyk

    Politechnika Wrocławska

  39. Functional and structural interplay between two mitochondrial inner membrane proteases, AtFTSH4 and AtOMA1, in Arabidops...

    Call: OPUS 14 , Panel: NZ2

    Principal investigator: prof. Hanna Elżbieta Jańska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  40. Cellular proteases during coronaviral infection

    Call: OPUS 14 , Panel: NZ6

    Principal investigator: dr hab. Krzysztof Pyrć

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  41. Novel inhibitors of herpes virus protease

    Call: PRELUDIUM 14 , Panel: NZ6

    Principal investigator: Magdalena Anna Pachota

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  42. The development of classic and aggregation- induced emission activity- based probes for human caspases.

    Call: PRELUDIUM 13 , Panel: ST5

    Principal investigator: Katarzyna Małgorzata Groborz

    Politechnika Wrocławska

  43. An integrated screening platform for determination of human proteasomes extended substrate specificity

    Call: OPUS 13 , Panel: ST5

    Principal investigator: prof. Marcin Drąg

    Politechnika Wrocławska

  44. SLPI-dependent cutaneous antimicrobial and antiviral immunity.

    Call: OPUS 13 , Panel: NZ6

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  45. The structural and functional characterization of Tpr, calpain-like peptidase and important virulence factor of Porphyro...

    Call: PRELUDIUM 13 , Panel: NZ1

    Principal investigator: dr Dominika Kamila Staniec

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  46. SLPI - novel regulator involved in the neuro-immune interplay in psoriasis

    Call: SONATA 12 , Panel: NZ6

    Principal investigator: dr Beata Katarzyna Grygier

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  47. Investigating the role of human tissue kallikreins in regulating matrix metalloproteinase activity.

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: Katherine Monique Falkowski

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  48. The effect of crowded environment on the catalytic activity and dynamics of viral proteases

    Call: OPUS 12 , Panel: NZ1

    Principal investigator: prof. Joanna Dominika Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  49. In vivo role of transient ECM protease activity in synaptic plasticity

    Call: PRELUDIUM 11 , Panel: NZ3

    Principal investigator: Marta Magnowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  50. Physiological characterization of the HtrA4 protease, including its role in apoptosis.

    Call: PRELUDIUM 11 , Panel: NZ3

    Principal investigator: dr Tomasz Jacek Wenta

    Uniwersytet Gdański, Wydział Biologii

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