Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Design, chemical synthesis and biological activity of inhibitors of matriptase-2.

2014/13/N/ST5/01299

Keywords:

matriptase-2 serine proteinases inhibitors peptides

Descriptors:

  • ST5_16:
  • ST5_23:
  • NZ1_2: Biochemistry

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Gdański, Wydział Chemii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Agata Gitlin-Domagalska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 7 - announced on 2014-03-17

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2015-02-12

Project end date (Y-m-d): 2018-02-11

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Platforma do wytrząsarki typ 358A.
  2. Wyparka próżniowa (20 000 PLN)
  3. Zespół napędowy do wytrząsarki typ 358A.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. Matriptase-2: monitoring and inhibiting its proteolytic activity
    Authors:
    Gitlin-Domagalska A., Mangold M., Dębowski D., Łęgowska A., Gütschow M., Rolka K.,
    Academic press:
    Future Med. Chem. (rok: 2018, tom: 10, strony: 2745–2761), Wydawca: Future Science
    Status:
    Published
    DOI:
    0.4155/fmc-2018-0346 - link to the publication
  2. Design and chemical syntheses of potent matriptase-2 inhibitors based on trypsin inhibitor SFTI-1 isolated from sunflower seeds
    Authors:
    Gitlin-Domagalska A., Dębowski D., Łęgowska A., Stirnberg M., Okońska J., Gütschow M., Rolka K.
    Academic press:
    Biopolymers. Peptide Science (rok: 2017, tom: 108, strony: e23031), Wydawca: New York, NY : Wiley
    Status:
    Published
    DOI:
    10.1002/bip.23031 - link to the publication
  3. Inhibitors of Matriptase-2 Based on the Trypsin Inhibitor SFTI-1.
    Authors:
    Gitlin A., Dębowski D., Karna N., Łęgowska A., Stirnberg M., Gütschow M., Rolka K.
    Academic press:
    ChemBioChem (rok: 2015, tom: 16, strony: 1601-1607), Wydawca: WILEY-BLACKWELL
    Status:
    Published
    DOI:
    10.1002/cbic.201500200 - link to the publication
  1. Designing and chemical syntheses of selective matriptase-2 inhibitors based on trypsin inhibitor SFTI-1 isolated from sunflower seeds
    Authors:
    Gitlin-Domagalska A., Dębowski D., Ptaszyńska (Karna) N., Łęgowska A., Stirnberg M., Gütschow M., Rolka K
    Conference:
    34th European Peptide Symposium (rok: 2017, ), Wydawca: European Peptide Society, Proceedings of the 34th European Peptide Symposium and the 8th International Peptide Symposium, edited by: A. Beck-Sickinger, K. Mörl, K. Bellmann-Sickert, S. Els-Heindl.
    Data:
    konferencja 04-09.09.2016
    Status:
    Published
    DOI:
    link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy