Projects funded by the NCN
Determination of the structural elements responsible for the narrow substrate specificity of staphylococcal proteases SplB and SplD
2011/01/N/NZ1/00208
Keywords:
Staphylococcus aureus extracellular Staphylococcal proteases inhibition of serine proteases protease-inhibitor complex chymotrypsin-like fold
Descriptors:
- NZ1_4: Structural biology
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 1 - announced on 2011-03-15
Amount awarded: 99 840 PLN
Project start date (Y-m-d): 2011-12-06
Project end date (Y-m-d): 2013-06-05
Project duration:: 18 months (the same as in the proposal)
Project status: Project settled
Information in the final report
- Publication in academic press/journals (2)
- Biochemical and structural characterization of SplD protease from Staphylococcus aureusAuthors:Zdzalik M., Kalinska M., Cichon P., Wysocka M., Stec-Niemczyk J., Stennicke H. R., Jabaiah A., Markiewicz M., Wladyka B., Daugherty P.S., Lesner A., Rolka K., Dubin A., Potempa J., Dubin G.Academic press:PLoS One (rok: 2013, tom: -, strony: -), Wydawca: Public Library of ScienceStatus:Accepted for publicationDOI:
- Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureusAuthors:Ewa Burchacka, Michal Zdzalik, Justyna-Stec Niemczyk, Katarzyna Pustelny, Grzegorz Popowicz, Benedykt Wladyka, Adam Dubin, Jan Potempa, Marcin Sienczyk, Grzegorz Dubin and Jozef OleksyszynAcademic press:Protein Science (rok: 2013, tom: -, strony: -), Wydawca: Wiley-BlackwellStatus:Accepted for publicationDOI: