Unnatural amino acids as a tool for optimization of substrates architecture for targeting human cysteine protease, cathepsin L.
2013/09/N/ST5/02448
Keywords
Descriptors
- ST5_16: Chemia biologiczna
- ST5_23: Chemia organiczna
Panel
ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution
Politechnika Wrocławska, Wydział Chemiczny
Voivodeship: dolnośląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 5 – announced on 2013-03-15
- Amount awarded
- 100 000 PLN
- Project start date
- 2014-04-04
- Project end date
- 2015-11-30
- Project duration
- 20 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (1)
-
Selective imaging of human cathepsin L in breast cancer by fluorescent activity-based probes
- Authors:
- Poreba M, Rut W, Vizovisek M, Groborz K, Kasperkiewicz P, Finlay D, Vuori K, Turk D, Turk B, Salvesen GS, Drag M
- Status:
- Accepted for publication
Articles in post-conference publications (3)
-
Zastosowanie nienaturalnych aminokwasów w bibliotekach substratów fluorogenicznych do badania enzymów proteolitycznych
- Authors:
- Poreba M, Kasperkiewicz P, Rut W, Snipas S, Mihelic M, Turk B, Salvesen G, Drag M
- Conference:
- II Ogólnopolskie Sympozium Interdyscyplinarne, Inter-Mix 2014 (year: 2014, pages: brak - poster), Publisher: Klub Stypendystów Fundacji na Rzecz Nauki Polskiej
- Date:
- conference 20-23 listopada 2014
- Status:
- Published
-
HyCoSuL approach of the optimization of cathepsin L substrate specificity
- Authors:
- Poreba M, Kasperkiewicz P, Turk B, Drag M
- Conference:
- XXXII Winter School on Proteinases and Their Inhibitors (year: 2015, pages: brak), Publisher: Salzburg Universitat
- Date:
- conference 25 lutego - 03 marca
- Status:
- Published
-
Specific labeling of cathepsins B and L in cancer cells using fluorescent activity based probes
- Authors:
- Poreba M, Rut W, Groborz K, Kasperkiewicz P, Vizovisek M, Finlay D, Turk D, Turk B, Salvesen GS, Drag M
- Conference:
- XXXIVth Winter School on Proteinases and Their Inhibitors (year: 2017, pages: brak), Publisher: Salzburg Universitat
- Date:
- conference 8 - 12 marca
- Status:
- Published