Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Extracellular proteolytic activity of human epithelium - role in the modulation of signal transduction.

2013/08/W/NZ1/00696

Keywords:

protease signalling imaging substrate specificity inhibitor

Descriptors:

  • NZ1_1:
  • NZ1_2:
  • NZ1_4:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jan Stanislaw Potempa 

Number of co-investigators in the project: 17

Call: SYMFONIA 1 - announced on 2012-12-15

Amount awarded: 6 500 000 PLN

Project start date (Y-m-d): 2013-12-09

Project end date (Y-m-d): 2018-06-08

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  1. Kallikrein 13: a new player in coronaviral infections
    Authors:
    Aleksandra Milewska, Katherine Falkowski, Magdalena Kalinska, Ewa Bielecka, Antonina Naskalska, Pawel Mak, Adam Lesner, Marek Ochman, Maciej Urlik, Elftherios Diamandis, Ioannis Prassas, Jan Potempa, Tomasz Kantyka, Krzysztof Pyrc
    Academic press:
    Science Signaling (rok: 2020, tom: 13, strony: b.d), Wydawca: Science
    Status:
    Published
    DOI:
    10.1126/scisignal.aba9902 - link to the publication
  2. Kallikreins - The melting pot of activity and function
    Authors:
    Magdalena Kalinska Ulf Meyer-Hoffert Tomasz Kantyka Jan Potempa
    Academic press:
    Biochimie (rok: 2016, tom: 122, strony: 270-82), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biochi.2015.09.023 - link to the publication
  3. Gingipains of Porphyromonas gingivalis Affect the Stability and Function of Serine Protease Inhibitor of Kazal-type 6 (SPINK6), a Tissue Inhibitor of Human Kallikreins.
    Authors:
    Plaza K, Kalinska M, Bochenska O, Meyer-Hoffert U, Wu Z, Fischer J, Falkowski K, Sasiadek L, Bielecka E, Potempa B, Kozik A, Potempa J, Kantyka T
    Academic press:
    Journal of Biological Chemistry (rok: 2016, tom: 36, strony: 18753-64), Wydawca: American Society of Biochemistry and Molecular Biology
    Status:
    Published
    DOI:
    10.1074/jbc.M116.722942 - link to the publication
  4. Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)—A CleavEx Based Analysis
    Authors:
    Katherine Falkowski, Ewa Bielecka, Ida B. Thøgersen, Oliwia Bocheńska, Karolina Płaza, Magdalena Kalińska, Laura Sąsiadek, Małgorzata Magoch, Aleksandra Pęcak, Magdalena Wiśniewska, Natalia Gruba, Magdalena Wysocka, Anna Wojtysiak, Magdalena Brzezińska-Bodal, Kamila Sychowska, Anastasija Pejkovska, Maren Rehders, Georgina Butler, Christopher M Overall, Klaudia Brix, Grzegorz Dubin, Adam Lesner, Andrzej Kozik, Jan J. Enghild, Jan Potempa, Tomasz Kantyka
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21(12), strony: 4383), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21124383 - link to the publication

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