Projects funded by the NCN
CleavEx - universal system for natural aminoacid sequence exposition for proteolytic enzymes specificity analysis
2012/07/N/NZ1/00006
Keywords:
proteases metalloproteinases MMP gingipains proteolysis substrate specificity
Descriptors:
- NZ1_2: Biochemistry
- NZ1_1: Molecular biology
- NZ1_5: Genetic engineering
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 4 - announced on 2012-09-15
Amount awarded: 100 000 PLN
Project start date (Y-m-d): 2013-08-29
Project end date (Y-m-d): 2015-08-28
Project duration:: 24 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Wirówka z chłodzeniem na probówki typu "falcon" 15 i 50 ml wraz z rotorem i wyposażeniem (25 000 PLN)
- Zestaw do elektroforezy.
- Wytrząsarka o ruchu kołowo-falowym, wraz z platformą 335x335 mm (5 000 PLN)
Information in the final report
- Publication in academic press/journals (1)
- Gingipains of Porphyromonas gingivalis Affect the Stability and Function of Serine Protease Inhibitor of Kazal-type 6 (SPINK6), a Tissue Inhibitor of Human Kallikreins.Authors:Plaza K, Kalinska M, Bochenska O, Meyer-Hoffert U, Wu Z, Fischer J, Falkowski K, Sasiadek L, Bielecka E, Potempa B, Kozik A, Potempa J, Kantyka T.Academic press:Journal of Biological Chemistry (rok: 2016, tom: 2, strony: 18753-64), Wydawca: American Society for Biochemistry and Molecular BiologyStatus:PublishedDOI:10.1074/jbc.M116.722942 - link to the publication