Projects funded by the NCN

The impact of H3 histamine receptor modulation on oligodendrogenesis and neurogenesis: a new strategy for the treatment ...

Call: PRELUDIUM 24 , Panel: NZ5

Principal investigator: Maciej Degutis

Instytut Farmakologii PAN

"Integrated Fixed-Dose Combination Drugs in Depression Therapy: A New Standard of Treatment and Mechanism of Action Stud...

Call: OPUS 28 , Panel: NZ7

Principal investigator: prof. Gabriel Piotr Nowak

Instytut Farmakologii PAN

Carbamylation in vascular calcification: new look at the hypertension etiology

Call: OPUS 27 , Panel: NZ5

Principal investigator: prof. Piotr Mateusz Mydel

Uniwersytet Jagielloński

New Insight into the Mechanism of Action of Antibiotic Peptides - The Role of the Electric Double Layer

Call: OPUS 27 , Panel: ST4

Principal investigator: prof. Sławomir Marcin Sęk

Uniwersytet Warszawski

Search for new biomarkers useful in the diagnosis of adrenal tumors based on the analysis of selected metabolomic profil...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Alicja Szatko

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

The gut virome - a new important microbiome component in autism spectrum disorder

Call: SONATINA 8 , Panel: NZ5

Principal investigator: dr Kinga Eryka Gawlińska

Uniwersytet Jagielloński

Philosophical-logical foundations of mechanistic causation

Call: SONATINA 8 , Panel: HS1

Principal investigator: dr Michał Oleksowicz

Uniwersytet Mikołaja Kopernika

Mechanizm of ionic surfactant - polyelectrolyte interactions in the process of formation of new generation of nanocarrie...

Call: OPUS 2 , Panel: ST4

Principal investigator: prof. Piotr Warszyński

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

New insight into the mechanism of cytotoxic brain edema in acute liver failure: focus on the functionality of mitochondr...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Mariusz Paweł Popek

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Cellular senescence as a new mechanism in development and progression of head and neck cancer

Call: OPUS 26 , Panel: NZ5

Principal investigator: prof. Michał Mateusz Masternak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Multifunctional composites with broad bone and periodontal regeneration potential - a comprehensive approach to obtain n...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr hab. Anna Osyczka

Uniwersytet Jagielloński, Wydział Biologii

Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophie...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Xiaonan Liu

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Anna Krętowska-Grunwald

Uniwersytet Medyczny w Białymstoku

New applications of non-conventional nonempirical methodologies for the analysis of catalytic and inhibitory properties ...

Call: OPUS 25 , Panel: ST4

Principal investigator: dr Edyta Dyguda-Kazimierowicz

Politechnika Wrocławska

A new approach for gene delivery into retinal bipolar cells

Call: OPUS 24 , Panel: NZ5

Principal investigator: dr hab. Andrzej Tomasz Foik

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

Searching for new chemical compounds inducing resistance of apple to diseases and determination of the molecular mechani...

Call: SONATA 18 , Panel: NZ9

Principal investigator: dr Artur Mikiciński

Instytut Ogrodnictwa

Oncogene competition - a new interplay mechanism of mutant p53 with CMYC and mutant KRAS in human cancers.

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr hab. Dawid Włodzimierz Walerych

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

A new approach to analyzing the luminescence quenching of Cr3+ activated oxides using the photoconductivity temperature ...

Call: PRELUDIUM 21 , Panel: ST3

Principal investigator: dr Natalia Majewska

Uniwersytet Gdański, Wydział Matematyki, Fizyki i Informatyki

The SnRK2 kinases as key proteins in seeds biology- unraveling new molecular mechanisms determining seed germination abi...

Call: OPUS 23 , Panel: NZ3

Principal investigator: dr Anna Marta Kulik

Instytut Biochemii i Biofizyki PAN

Development of a new laser materials used to giant pulse formation: Study of the loss control mechanism in Cr-doped garn...

Call: OPUS 23 , Panel: ST5

Principal investigator: Mykhailo Chaika

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

The application of artificial intelligence to the discovery of new natural drugs with mechanisms aimed at lowering free ...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Maciej Spiegel

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Farmaceutyczny

New strategy for overcoming resistance to chemotherapy of ovarian cancer by modulation of the canonical and non-canonica...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Radosław Januchowski

Uniwersytet Zielonogórski, Collegium Medicum

New mechanisms determining MFT-mediated sensitivity to abscisic acid during the germination of Medicago truncatula seeds

Call: OPUS 22 , Panel: NZ3

Principal investigator: dr Joanna Banasiak

Instytut Chemii Bioorganicznej PAN

The role of Candida albicans' plasma membrane sphingolipids in the potentially new mechanism of drug resistance and in t...

Call: OPUS 22 , Panel: NZ1

Principal investigator: dr hab. Anna Janina Krasowska

Uniwersytet Wrocławski, Wydział Biotechnologii

Heart & brain interactions as a new approach to understanding the relationship between exercise and mood.

Call: SONATA 17 , Panel: HS6

Principal investigator: dr Tomasz Stanisław Ligęza

Uniwersytet Jagielloński, Wydział Filozoficzny

Identification and characterization of new genetic variants associated with disturbances in the metabolism of biogenic a...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Magdalena Rygiel

Instytut Matki i Dziecka

Role of unconventional myosin VI in development of cardiomyopathy: New insights into understanding of function and dysfu...

Call: PRELUDIUM BIS 3 , Panel: NZ5

Principal investigator: prof. Maria Jolanta Rędowicz

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Anna Piotrowska-Murzyn

Instytut Farmakologii PAN

Investigation of the MLK4 biology in breast cancer and search for new therapeutic strategies using innovative PROTAC com...

Call: SONATA BIS 11 , Panel: NZ5

Principal investigator: dr Anna Agnieszka Marusiak

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Role of Mcpip1 in biliary pathobiology: new potential therapeutic opportunities

Call: SONATA BIS 11 , Panel: NZ5

Principal investigator: dr Jerzy Kotlinowski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Mitochondria-targeting conjugates as a new anticancer agents

Call: OPUS 21 , Panel: ST4

Principal investigator: prof. Adam Włodzimierz Huczyński

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

New mechanicism and theology

Call: PRELUDIUM 20 , Panel: HS1

Principal investigator: dr Michał Oleksowicz

Uniwersytet Mikołaja Kopernika, Wydział Teologiczny

Reversible senescence as a new mechanism of cancer cell resistance for chemotherapy. Analysis of the mechanism of cancer...

Call: SONATINA 5 , Panel: NZ3

Principal investigator: dr Karolina Anna Staniak

Politechnika Warszawska, Wydział Chemiczny

A new class of antimicrobial compounds. Design, synthesis and study of the mechanism of action.

Call: PRELUDIUM BIS 2 , Panel: NZ7

Principal investigator: dr hab. Sylwia Anna Rodziewicz-Motowidło

Uniwersytet Gdański, Wydział Chemii

Semantics out of the grey box: How can representational mechanisms of the brain provide semantic properties of structura...

Call: PRELUDIUM BIS 2 , Panel: HS1

Principal investigator: dr hab. Marcin Tomasz Miłkowski

Instytut Filozofii i Socjologii Polskiej Akademii Nauk

The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Paulina Anna Tokarz

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Iron chelators as tyrosine kinase inhibitors - a new strategy for the treatment of glioblastoma multiforme

Call: PRELUDIUM BIS 2 , Panel: NZ5

Principal investigator: dr hab. Anna Dominika Mrozek-Wilczkiewicz

UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

Identification of the interdependence between SWI/SNF-type chromatin remodeling complex, metabolism control and RNA modi...

Call: OPUS 20 , Panel: NZ5

Principal investigator: prof. Tomasz Jacek Sarnowski

Instytut Biochemii i Biofizyki PAN

Profiling of microRNA expression in canine mammary tumours as a new tool in veterinary oncology

Call: OPUS 2 , Panel: NZ5

Principal investigator: dr hab. Magdalena Król

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

Polymersomes specifically releasing cGAMP and doxorubicin in tumor hypoxic regions as a new anti-cancer therapeutic stra...

Call: OPUS 20 , Panel: NZ5

Principal investigator: dr hab. Ryszard Smolarczyk

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Dissecting cancer activome to develop new generation of antibody-drug conjugates

Call: OPUS 20 (LAP) , Panel: NZ5

Principal investigator: dr hab. Marcin Łukasz Poręba

Politechnika Wrocławska

Circular RNAs, new biomarkers panel and machine learning in prediction of acute kidney injury prediction in adult, hemat...

Call: PRELUDIUM BIS 2 , Panel: NZ5

Principal investigator: prof. Jolanta Małyszko

Warszawski Uniwersytet Medyczny

Uracil in DNA and aberrant DNA methylation/hydroxymethylation as a new biomarkers of multiple myeloma development? A sea...

Call: OPUS 20 , Panel: NZ5

Principal investigator: prof. Ryszard Oliński

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

In search for new mechanisms of maize adaptation to cool spring conditions

Call: OPUS 20 , Panel: NZ9

Principal investigator: prof. Paweł Mieczysław Sowiński

Uniwersytet Warszawski, Wydział Biologii

Digital entrepreneurs and Industry 4.0. The key mechanism of the new path creation in the industrial regions?

Call: OPUS 20 , Panel: HS4

Principal investigator: dr hab. Krzysztof Gwosdz

Uniwersytet Jagielloński, Wydział Geografii i Geologii

A new approach to the development of a universal model of the gasochromic phenomenon based on a comprehensive analysis o...

Call: SONATA 16 , Panel: ST5

Principal investigator: dr hab. Michał Marek Mazur

Politechnika Wrocławska

Atopic Dermatitis - searching for new strategic points of treatment, by evaluating clinical and prognostic significance ...

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Anna Maria Zaryczańska

Gdański Uniwersytet Medyczny, Wydział Lekarski

New mechanisms regulating acetylcholine receptors at the neuromuscular junction

Call: OPUS 19 , Panel: NZ3

Principal investigator: dr hab. Tomasz Jacek Prószyński

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Qualified majorities in counter-majoritarian mechanisms: Towards a new theory of supermajorities in judicial review.

Call: POLS , Panel: HS5

Principal investigator: dr Mauro Arturo Rivera Leon

UNIWERSYTET ŚLĄSKI, Wydział Prawa i Administracji

Chasing the HARE: elucidation of the binding mechanism of the new and unexplored ligandsof the Hyaluronic Acid Receptor ...

Call: SONATINA 4 , Panel: NZ1

Principal investigator: dr Aleksandra Anna Twarda-Cłapa

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności