Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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A study on the epigenetic mechanisms as new risk factors for development of diabetic neuropathy in diabetes mellitus type 1.

2014/13/B/NZ4/00149

Keywords:

diabetes mellitus epigenetics miRNA DNA methylation neuropathy

Descriptors:

  • NZ4_11: Metabolism
  • NZ2_2: Genomics, transcriptomics, epigenomics

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński-Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Beata Kieć-Wilk 

Number of co-investigators in the project: 5

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 794 300 PLN

Project start date (Y-m-d): 2015-02-11

Project end date (Y-m-d): 2018-12-10

Project duration:: 46 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  1. Epigenetic mechanism in search for the pathomechanism of diabetic neuropathy development in diabetes mellitus type 1 (T1DM).
    Authors:
    Joanna Gastoł, Przemysław Kapusta, Anna Polus, Ewelina Pitera, Maria Biela, Paweł Wołkow, Łukasz Pawliński, Beata Kieć- Wilk,
    Academic press:
    Endocrine (rok: 2020, tom: -, strony: Jan 4 [Epub ahead of print]), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12020-019-02172-9. - link to the publication
  2. Neuropatia autonomiczna układu sercowo-naczyniowego w przebiegu cukrzycy – aktualny stan wiedzy
    Authors:
    Joanna Gastoł, Łukasz Pawliński, Beata Kieć-Wilk
    Academic press:
    Postępy Biochemii (rok: 2019, tom: 65(4), strony: 306-312), Wydawca: Polish Biochemical Society
    Status:
    Published
    DOI:
    10.18388/pb.2019_287 - link to the publication
  3. Specific gene expression in type 1 diabetic patients with and without cardiac autonomic neuropathy.
    Authors:
    Joanna Gastol, Anna Polus, Maria Biela, Urszula Razny, Lukasz Pawlinski, Agnieszka Ludwig – Slomczynska, Bogdan Solnica, Pawel Wołkow, Beata Kiec-Wilk
    Academic press:
    Scientific Reports (rok: 2020, tom: -, strony: -), Wydawca: nature journal
    Status:
    Accepted for publication
  4. Is our treatment in type 1 diabetes mellitus (insulin therapy models, metabolic control) optimal for preventing cardiovascular autonomic neuropathy?
    Authors:
    Lukasz Pawlinski, Joanna Gastol, Mateusz Fiema, Bartlomiej Matejko, Beata Kiec-Wilk
    Academic press:
    Endokrynolgia Polska (rok: 2019, tom: 70(4), strony: 323-329), Wydawca: VIA MEDICA Journals
    Status:
    Published
    DOI:
    10.5603/EP.a2019.0011. - link to the publication