Projects funded by the NCN
Double face of erythropoietin - finding a new mechanisms of action in an experimental model of human colon cancer
2013/09/N/NZ5/00830
Keywords:
erythropoietin colon cancer mouse therapy
Descriptors:
- NZ5_7: Human disease treatment
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej
woj. podlaskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 5 - announced on 2013-03-15
Amount awarded: 136 440 PLN
Project start date (Y-m-d): 2014-03-20
Project end date (Y-m-d): 2017-03-19
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Information in the final report
- Publication in academic press/journals (2)
- Erythropoietin accelerates tumor growth through increase of erythropoietin receptor (EpoR) as well as by the stimulation of angiogenesis in DLD-1 and Ht-29 xenograftsAuthors:Tankiewicz-Kwedlo A, Hermanowicz J, Surażynski A, Rożkiewicz D, Pryczynicz A, Domaniewski T, Pawlak K, Kemona A, Pawlak DAcademic press:Mol Cell Biochem (rok: 2016, tom: 421, strony: 45309), Wydawca: SpringerStatus:PublishedDOI:10.1007/s11010-016-2779-x - link to the publication
- Erythropoietin enhances the cytotoxic effect of hydrogen peroxide on colon cancer cellsAuthors:Tankiewicz-Kwedlo A, Hermanowicz J, Surażynski A, Kwedlo W, Rożkiewicz D, Pawlak K, Domaniewski T, Pawlak DAcademic press:Current Pharmaceutical Biotechnology (rok: 2017, tom: 18, strony: 127-137), Wydawca: Bentham ScienceStatus:PublishedDOI:10.2174/1389201018666161116092907 - link to the publication