Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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New mechanisms of alkylating damage repair in environmentally relevant bacteria: Shewanella oneidensis and Pseudomonas putida.

2012/05/B/NZ1/00693

Keywords:

Shewanella oneidensis Pseudomonas putida alkylating agents DNA repair facultative anaerobes

Descriptors:

  • NZ1_10: Microbiology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Anna Sikora 

Number of co-investigators in the project: 6

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 508 685 PLN

Project start date (Y-m-d): 2013-01-29

Project end date (Y-m-d): 2017-01-28

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Stacja robocza (4 000 PLN)
  2. Termocykler (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  1. Pseudomonas putida AlkA and AlkB Proteins Comprise Different Defense Systems for the Repair of Alkylation Damage to DNA – In Vivo, In Vitro, and In Silico Studies
    Authors:
    MIELECKI D., SAUMAA S., WRZESIŃSKI M., MACIEJEWSKA A.M., ŻUCHNIEWICZ K., SIKORA A., PIWOWARSKI J., NIEMINUSZCZY J., KIVISAAR M., GRZESIUK E.
    Academic press:
    PLOS ONE (rok: 2013, tom: 8 (10), strony: e76198), Wydawca: PLOS
    Status:
    Published
    DOI:
    10.1371/journal.pone.0076198 - link to the publication
  2. Ada response – a strategy for repair of alkylated DNA in bacteria
    Authors:
    Mielecki D., Grzesiuk E.
    Academic press:
    FEMS Microbiology Letters (rok: 2014, tom: 355, strony: 1–11), Wydawca: Federation of European Microbiological Societies
    Status:
    Published
    DOI:
    10.1111/1574-6968.12462 - link to the publication
  3. Evaluation of the Escherichia coli HK82 and BS87 strains as tools for AlkB studies.
    Authors:
    Mielecki D, Sikora A, Wrzesiński M, Nieminuszczy J, Detman A, Żuchniewicz K, Gromadka R, Grzesiuk E
    Academic press:
    DNA Repair (rok: 2016, tom: 39, strony: 34–40), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dnarep.2015.12.010 - link to the publication
  1. NEW PATHWAYS INVOLVED IN THE RESPONSE TO DNA DAMAGE IN BACTERIA
    Authors:
    Damian Mielecki, Olga Niezgoda (nee Kasprzak), Anna Sikora, Elżbieta Grzesiuk
    Conference:
    2 nd Dynamic DNA and RNA Structures in Damage Responses & Cancer Conference (rok: 2016, ), Wydawca: Fusion Conferences Ltd
    Data:
    konferencja 22-25.02.2016
    Status:
    Published
  2. Pseudomaonas putida AlkA and AlkB proteins comprise different defense systems for the repair of alkylation damage to DNA
    Authors:
    MIELECKI D., WRZESIŃSKI M., MACIEJEWSKA A.M., SIKORA A., GRZESIUK E.
    Conference:
    11th International Conference on Environmental Mutagenesis, XI Congres of SBMCTA and (rok: 2013, ), Wydawca: Organizator konferencji
    Data:
    konferencja 3-8 November
    Status:
    Published