Antihypertensive properties of rapeseed-derived peptides in rats. Potential role of the new mechanisms of ang I conversion.

2011/01/B/NZ4/05703

Keywords

Descriptors

  • NZ4_2: Fizjologia
  • NZ4_4: Patofizjologia ogólna

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Elżbieta Kompanowska-Jezierska

Number of co-investigators in the project: 8

Call

OPUS 1 – announced on 2011-03-15

Amount awarded
490 000 PLN
Project start date
2011-12-15
Project end date
2015-06-14
Project duration
42 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Zamrażarka do głębokiego mrożenia. Cost: 40 500 PLN
  2. pH-metr. Cost: 2 750 PLN

Information in the final report

Publication in academic press/journals (1)

  1. Effects of chymostatin, a chymase inhibitor, on blood pressure, plasma and tissue angiotensin II, and renal haemodynamics in hypertensive rats

    Authors:
    Malwina Monika Roszkowska-Chojecka, Agnieszka Walkowska, Olga Gawrys, Iwona Baranowska, Małgorzata Kalisz, Anna Litwiniuk, Lidia Martyńska, and Elżbieta Kompanowska-Jezierska
    Academic press:
    Experimental Physiology (year: 2015, volume: 46168, pages: xxxx), Publisher: Wiley-Blackwell
    Status:
    Published
    DOI:
    10.1113/EP085325. – link to the publication

Articles in post-conference publications (3)

  1. Effects of simultaneous inhibition of chymase and angiotensin converting enzyme on blood pressure and kidney haemodynamics in spontaneously hypertensive rats

    Authors:
    M. M. Roszkowska-Chojecka, A. Walkowska, E. Kompanowska-Jezierska
    Conference:
    26th Congress of the Polish Physiological Society (year: 2014, pages: 113), Publisher: Polish Physiological Society
    Date:
    conference September 18-20
    Status:
    Published
  2. Effects of chronic treatment with non-ACE angiotensin conversion inhibitors on blood pressure and metabolic parameters in spontaneously hypertensive rats

    Authors:
    I. Baranowska, B. Badzynska, O. Gawrys, M. Roszkowska-Chojecka, K.H. Olszyński, E. Kompanowska-Jezierska
    Conference:
    26th Congress of the Polish Physiological Society (year: 2014, pages: 109), Publisher: Polish Physiological Society
    Date:
    conference September 18-20
    Status:
    Published
  3. Effects of chymostatin, a chymase inhibitor, on blood pressure and kidney haemodynamics in spontaneously hypertensive rats

    Authors:
    M. Roszkowska-Chojecka, A. Walkowska, E. Kompanowska-Jezierska
    Conference:
    Joint Meeting ESH-ISH, Hypertension (year: 2014, pages: 544), Publisher: Wolters Kluwer
    Date:
    conference June 13-16
    Status:
    Published
    DOI:
    link to the publication

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Graphic design and implementation: Jakub Piotrowski