Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Mechanism and efficiency of nanoencapsulated photosensitisers delivery in model conditions and in micorsystems.

2012/07/B/ST5/02753

Keywords:

new materials nanoencapsulated photosensitisers photodynamic therapy lab-on-a-chip in vitro efficacy and mechanism

Descriptors:

  • ST5_10: Functional materials/nanomaterials, nanoparticles

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Warszawska, Wydział Chemiczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Zbigniew Brzózka 

Number of co-investigators in the project: 8

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 598 500 PLN

Project start date (Y-m-d): 2013-07-08

Project end date (Y-m-d): 2016-07-07

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. mikroskop steroskopowy (69 000 PLN)
  2. Źródła światła do terapii fotodynamicznej (29 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (3)
  1. Evaluation of nanoencapsulated verteporfin's cytotoxicity using a microfluidic system
    Authors:
    Kat arzyna Tokarska, Magdalena Buł ka, Urszula Bazylińska, Elżbieta Jastrzębska, Michał Chudy, Artur Dybko, Kazimiera A. Wilk, Zbigniew Brzózka
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (rok: 2016, tom: 127, strony: 39-48), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2016.02.052 - link to the publication
  2. Analysis of the efficiency of photodynamic therapy using a microsystem for mono-, co- and mixed cultures
    Authors:
    E. Jastrzebska , M. Bulka, N. Rybicka, K. Zukowski
    Academic press:
    Sensors and Actuators B: Chemical (rok: 2015, tom: 221, strony: 1356-1365), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.snb.2015.08.022 - link to the publication
  3. The effect of anionic dicephalic surfactants on fabrication of varied-core nanocarriers for sustained release of porphyrin photosensitizers
    Authors:
    U. Bazylinska; R. Frąckowiak; Z. Brzózka; K. A Wilk
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis , Wydawca: Elsevier
    Status:
    Submitted
  4. Microfluidic platform for photodynamic therapy cytotoxicity analysis of nanoencapsulated indocyanine-type photosensitizers
    Authors:
    Elzbieta Jastrzeebska, Urszula Bazylinska, Magdalena Bułka, KatarzynaTokarska, MichałChudy, ArturDybko, Kazimiera AnnaWilk, ZbigniewBrzozka
    Academic press:
    Biomicrofluidics (rok: 2016, tom: 1, strony: 45307), Wydawca: AIP Publishing
    Status:
    Published
    DOI:
    10.1063/1.4941681 - link to the publication
  1. NEW HIGHLY SELECTIVE PORPHYRIN-BASED NANOPHOTOSENSITIZER INVESTIGATED USING A MICROFLUIDIC SYSTEM
    Authors:
    K. Tokarska, E. Jastrzebska , M. Chudy, A. Dybko , U. Bazylinska , K. A. Wilk and Z. Brzozka
    Conference:
    20 th International Conference on Miniaturized Systems for Chemistry and Life Sciences (rok: 2016, ), Wydawca: Chemical and Biological Microsystems Society
    Data:
    konferencja 9-13 October 2016 - Dublin, IRELAND
    Status:
    Accepted for publication
  2. Anticancer photodynamic therapy based on the use of a microsystem
    Authors:
    E. Jastrzebska, N. Bulka, K. Zukowski, M. Chudy, Z. Brzozka, A. Dybko
    Conference:
    European Conference on Biomedical Optics (rok: 2015, ), Wydawca: SPIE
    Data:
    konferencja 21-25.03.2015
    Status:
    Published
  3. EVALUATION OF CYTO- AND PHOTOCYTOTOXICITY OF NEW NANOENCAPSULATED PHOTOSENSITIZERS IN THE MICROSYSTEM
    Authors:
    E. Jastrzebska, M.N. Bulka, K. Tokarska, U. Bazylinska, M. Chudy, A. Dybko, K.A. Wilk, Z. Brzozka 1 1
    Conference:
    19 th International Conference on Miniaturized Systems for Chemistry and Life Sciences October 25-29, 2015, Gyeongju, KOREA (rok: 2015, ), Wydawca: Chemical and Biological Microsystems Society
    Data:
    konferencja 25-29.10.2015
    Status:
    Published