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The new tools for research mechanisms of anticancer activity of photosenthisisers used for photodynamic therapy of cancer in in vitro and in vivo model

2014/15/B/NZ5/01488

Keywords

Descriptors

  • NZ5_7: Leczenie chorób człowieka
  • NZ5_3: Patogeneza chorób człowieka
  • NZ5_5: Diagnostyka chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Marek Arkadiusz Murias

Number of co-investigators in the project: 5

Call

OPUS 8 – announced on 2014-09-15

Amount awarded
848 121 PLN
Project start date
2015-07-24
Project end date
2021-01-23
Project duration
66 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. aparat do RSEPR. Cost: 200 000 PLN
  2. komora do badania hipoksji z inkubatorem. Cost: 150 000 PLN

Information in the final report

Publication in academic press/journals (6)

  1. Magnetic and electric properties of partially reduced graphene oxide aerogels.

    Authors:
    Krzysztof Tadyszak, Katarzyna Chybczyńska, Paweł Ławniczak, Alina Zalewska, Bogumił Cieniek, Michał Gonet, Marek Murias
    Academic press:
    Journal of Magnetism and Magnetic Materials (year: 2019, volume: 492, pages: art. 165656 [s. 1-9]), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jmmm.2019.165656 – link to the publication

  2. EPR Oximetry Sensor-Developing a TAM Derivative for In Vivo Studies.

    Authors:
    Boś-Liedke A, Walawender M, Woźniak A, Flak D, Gapiński J, Jurga S, Kucińska M, Plewiński A, Murias M, Elewa M, Lampp L, Imming P, Tadyszak K
    Academic press:
    Cell Biochemistry and Biophysics (year: 2017, volume: 76, pages: 19-28), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s12013-017-0824-3 – link to the publication

  3. Beyond mouse cancer models: Three-dimensional human-relevant in vitro and non-mammalian in vivo models for photodynamic therapy

    Authors:
    Malgorzata Kucinska, Marek Murias, Patrycja Nowak-Sliwinska
    Academic press:
    Mutation Research/Reviews in Mutation Research (year: 2017, volume: 773, pages: 242-262), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.mrrev.2016.09.002 – link to the publication

  4. Multiharmonic Electron Paramagnetic Resonance Imaging as an innovative approach for in vivo studies

    Authors:
    Michal Gonet, Mikolaj Baranowski, Tomasz Czechowski, Małgorzata Kucinska Adam Plewinski Piotr Szczepanik Stafan Jurga Marek Murias
    Academic press:
    Free Radicals Biology and Medicine (year: 2020, volume: 0, pages: 0), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2020.03.018 – link to the publication

  5. Modeling the photodynamic effect in 2D versus 3D cell culture under normoxic and hypoxic conditions

    Authors:
    Malgorzata Kucinska, Adam Plewinski, Wojciech Szczolko , Mariusz Kaczmarek , Tomasz Goslinski , Marek Murias
    Academic press:
    Free Radicals Biology and Medicine (year: 2021, volume: 162, pages: 309-326), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2020.10.304 – link to the publication

  6. Dynamic Electron Paramagnetic Resonance Imaging: Modern Technique for Biodistribution and Pharmacokinetic Imaging

    Authors:
    Mikolaj Baranowski, Michal Gonet, Tomasz Czechowski, Malgorzata Kucinska, Adam Plewinski, Piotr Szczepanik, Marek Murias
    Academic press:
    Journal of Physical Chemistry C (year: 2020, volume: 124, pages: 19743–19752), Publisher: ACS
    Status:
    Published
    DOI:
    10.1021/acs.jpcc.0c05703 – link to the publication

Articles in post-conference publications (1)

  1. Electron paramagnetic resonance imaging as a new tool for cancer imaging

    Authors:
    Michał Gonet, Adam Plewiński, Marek Murias
    Conference:
    14th European Molecular Imaging Meeting (year: 2019, pages: 00-00), Publisher: European Society of Molecular Imaging
    Date:
    conference 19-22 Marzec 2019
    Status:
    Published
    DOI:
    link to the publication

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Graphic design and implementation: Jakub Piotrowski