Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The new tools for research mechanisms of anticancer activity of photosenthisisers used for photodynamic therapy of cancer in in vitro and in vivo model

2014/15/B/NZ5/01488

Keywords:

photodynamic therapy cancer electron paramagnetic rezonanse photosensitizers xenografts

Descriptors:

  • NZ5_7: Human disease treatment
  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Marek Murias 

Number of co-investigators in the project: 5

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 848 121 PLN

Project start date (Y-m-d): 2015-07-24

Project end date (Y-m-d): 2021-01-23

Project duration:: 66 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. aparat do RSEPR (200 000 PLN)
  2. komora do badania hipoksji z inkubatorem (150 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (1)
  1. Beyond mouse cancer models: Three-dimensional human-relevant in vitro and non-mammalian in vivo models for photodynamic therapy
    Authors:
    Malgorzata Kucinska, Marek Murias, Patrycja Nowak-Sliwinska
    Academic press:
    Mutation Research/Reviews in Mutation Research (rok: 2017, tom: 773, strony: 242-262), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.mrrev.2016.09.002 - link to the publication
  2. Dynamic Electron Paramagnetic Resonance Imaging: Modern Technique for Biodistribution and Pharmacokinetic Imaging
    Authors:
    Mikolaj Baranowski, Michal Gonet, Tomasz Czechowski, Malgorzata Kucinska, Adam Plewinski, Piotr Szczepanik, Marek Murias
    Academic press:
    Journal of Physical Chemistry C (rok: 2020, tom: 124, strony: 19743–19752), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.jpcc.0c05703 - link to the publication
  3. Magnetic and electric properties of partially reduced graphene oxide aerogels.
    Authors:
    Krzysztof Tadyszak, Katarzyna Chybczyńska, Paweł Ławniczak, Alina Zalewska, Bogumił Cieniek, Michał Gonet, Marek Murias
    Academic press:
    Journal of Magnetism and Magnetic Materials (rok: 2019, tom: 492, strony: art. 165656 [s. 1-9]), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jmmm.2019.165656 - link to the publication
  4. Modeling the photodynamic effect in 2D versus 3D cell culture under normoxic and hypoxic conditions
    Authors:
    Malgorzata Kucinska, Adam Plewinski, Wojciech Szczolko , Mariusz Kaczmarek , Tomasz Goslinski , Marek Murias
    Academic press:
    Free Radicals Biology and Medicine (rok: 2021, tom: 162, strony: 309-326), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.304 - link to the publication
  5. EPR Oximetry Sensor-Developing a TAM Derivative for In Vivo Studies.
    Authors:
    Boś-Liedke A, Walawender M, Woźniak A, Flak D, Gapiński J, Jurga S, Kucińska M, Plewiński A, Murias M, Elewa M, Lampp L, Imming P, Tadyszak K
    Academic press:
    Cell Biochemistry and Biophysics (rok: 2017, tom: 76, strony: 19-28), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12013-017-0824-3 - link to the publication
  6. Multiharmonic Electron Paramagnetic Resonance Imaging as an innovative approach for in vivo studies
    Authors:
    Michal Gonet, Mikolaj Baranowski, Tomasz Czechowski, Małgorzata Kucinska Adam Plewinski Piotr Szczepanik Stafan Jurga Marek Murias
    Academic press:
    Free Radicals Biology and Medicine (rok: 2020, ), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2020.03.018 - link to the publication
  1. Electron paramagnetic resonance imaging as a new tool for cancer imaging
    Authors:
    Michał Gonet, Adam Plewiński, Marek Murias
    Conference:
    14th European Molecular Imaging Meeting (rok: 2019, ), Wydawca: European Society of Molecular Imaging
    Data:
    konferencja 19-22 Marzec 2019
    Status:
    Published
    DOI:
    link to the publication

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