Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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New mechanisms of cellular reprogramming: role of TLR3 and RIG-1 activation and downstream anti-inflammatory response to different viral vectors

2013/11/N/NZ1/02399

Keywords:

reprogramming human iPS cells TLR-3 RIG-1,HO-1 anti-inflammatory response Sendai vectors

Descriptors:

  • NZ1_1: Molecular biology
  • NZ3_1: Cell biology
  • NZ3_8: Stem cell biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Jacek Stępniewski 

Number of co-investigators in the project: 2

Call: PRELUDIUM 6 - announced on 2013-09-16

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2014-07-10

Project end date (Y-m-d): 2016-07-09

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  1. Generation of functional endothelial cells with progenitor-like features from murine induced pluripotent stem cells
    Authors:
    Neli Kachamakova-Trojanowska, Witold Nowak, Krzysztof Szade, Jacek Stępniewski, Karolina Bukowska-Strakova, Monika Żukowska, Antonina Chmura-Skirlinska, Michael Beilharz, Józef Dulak, Alicja Jozkowicz
    Academic press:
    Vacular Pharmacology (rok: 2016, tom: 86, strony: 94-108), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.vph.2016.07.008. - link to the publication
  2. Heme oxygenase-1 affects generation and spontaneous cardiac differentiation of induced pluripotent stem cells.
    Authors:
    Stepniewski J, Pacholczak T, Skrzypczyk A, Ciesla M, Szade A, Szade K, Bidanel R, Langrzyk A, Grochowski R, Vandermeeren F, Kachamakova-Trojanowska N, Jez M, Drabik G, Nakanishi M, Jozkowicz A, Dulak J.
    Academic press:
    IUBMB Life (rok: 2018, tom: 70, strony: 129-142), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/iub.1711. - link to the publication