Search results

101. Identification of Mycobacterium tuberculosis ligands binding human serum amyloid A (SAA) and biological function of tube…

Principal investigator: dr hab. Bożena Renata Dziadek

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 12, Panel: NZ7

102. The evaluation of the efficacy of alpha7 nicotinic acetylcholine receptor ligands in rat models of autism

Principal investigator: dr hab. Agnieszka Anna Nikiforuk

Instytut Farmakologii PAN

Call: OPUS 12, Panel: NZ7

103. Piperazine derivatives as active histamine H3 receptor ligands - molecular modeling, synthesis, pharmacological evaluati…

Principal investigator: Katarzyna Anna Szczepańska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 12, Panel: NZ7

104. Quantum nanomagnets based on metal complexes with unusual geometries and using new unusual ligands

Principal investigator: dr Dawid Pinkowicz

Uniwersytet Jagielloński, Wydział Chemii

Call: SONATA BIS 6, Panel: ST5

105. The role of halogen bonding in interaction of ligands with SERT.

Principal investigator: dr Jakub Staroń

Instytut Farmakologii PAN

Call: SONATA 11, Panel: NZ7

106. The optically pure aziridine rings as highly effective units to transfer of chirality to racemic or prochiral reagents. …

Principal investigator: dr hab. Michał Rachwalski

Uniwersytet Łódzki, Wydział Chemii

Call: OPUS 11, Panel: ST5

107. Development of method based on fluorescence polarization for high affinity ligand searching toward m7G nucleotide bindin…

Principal investigator: Anna Wojtczak

Uniwersytet Warszawski, Wydział Fizyki

Call: PRELUDIUM 11, Panel: ST4

108. Synthesis and biological evaluation of novel, drug-like multifunctional ligands, as potential anti-Alzheimer's agents ta…

Principal investigator: Dawid Marcin Panek

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 11, Panel: NZ7

109. Imine Cage-like Silsesquioxane as New Multifunctional Ligands in Supramolecular Chemistry.

Principal investigator: dr Mateusz Przemysław Janeta

Uniwersytet Wrocławski, Wydział Chemii

Call: PRELUDIUM 11, Panel: ST5

110. The determination of ADME-Tox in vitro for potential CNS-drug candidates acting as potent and selective ligands of serot…

Principal investigator: Annamaria Teresa Lubelska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 11, Panel: NZ7

111. Synthesis and pharmacological characterization of structurally diverse chemical analogues of compound PO-10 as multiple …

Principal investigator: dr hab. Agnieszka Zagórska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATA 11, Panel: NZ7

112. The effect of peroxisome proliferator activated receptor (PPAR) gamma ligands on cytokines synthesis in the porcine myom…

Principal investigator: dr Aleksandra Hanna Kurzyńska

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

Call: PRELUDIUM 11, Panel: NZ9

113. The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola…

Principal investigator: Karolina Sylwia Podkowa

Instytut Farmakologii PAN

Call: PRELUDIUM 10, Panel: NZ7

114. Synthesis of new palladium and ruthenium complexes bearing monoaminocarbene ligands and investigation of their catalytic…

Principal investigator: Jan Aleksander Lorkowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Call: PRELUDIUM 10, Panel: ST5

115. 5-HT6 receptor ligands as addition to antipsychotic therapy in schizophrenia - an impact on body weight, metabolic param…

Principal investigator: prof. Anna Małgorzata Wesołowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 10, Panel: NZ7

116. Synthesis and Struktural Characterization of Small-Molecule Probes for the Programmed Death 1/ Programmed Death Ligand 1…

Principal investigator: Katarzyna Agnieszka Guzik

Uniwersytet Jagielloński, Wydział Chemii

Call: PRELUDIUM 10, Panel: ST5

117. Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

Principal investigator: Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: HARMONIA 7, Panel: NZ7

118. New olefin metathesis catalysts containig a nitro group on the N-heterocyclic ligand

Principal investigator: dr Marta Malinowska

Uniwersytet w Białymstoku, Wydział Biologiczno-Chemiczny

Call: PRELUDIUM 9, Panel: ST5

119. Traizine 5-HT6 receptor ligands - new perspective for therapy of current civilization CNS-diseases

Principal investigator: dr hab. Jadwiga Handzlik

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 9, Panel: NZ7

120. Quaternary pyridinium salts- new ligands in te complexation process of metal ions in a biphasic system

Principal investigator: Aleksandra Maria Wojciechowska

Politechnika Poznańska, Wydział Technologii Chemicznej

Call: PRELUDIUM 9, Panel: ST8

121. Role of tryptophan-derived AhR ligands in UVB-induced melanomagenesis - in vitro and in vivo studies

Principal investigator: dr Katarzyna Walczak

Uniwersytet Medyczny w Lublinie, Wydział Nauk o Zdrowiu

Call: SONATA 9, Panel: NZ7

122. Synthesis and characterization of new nickel catalysts bearing N-heterocyclic ligands and their use in carbene polymeriz…

Principal investigator: Agata Anna Włodarska

Politechnika Warszawska, Wydział Chemiczny

Call: PRELUDIUM 8, Panel: ST5

123. Ruthenium Olefin Metathesis Catalysts Bearing Electron Rich Ligands: a Profitable Combination

Principal investigator: prof. Karol Lesław Grela

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 8, Panel: ST5

124. Synthesis and physicochemical properties of lanthanide complexes with heterocyclic ligands and their application for spe…

Principal investigator: prof. Jerzy Kazimierz Hanuza

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

Call: OPUS 8, Panel: ST5

125. Rhodium and Platinum complexes with ionic liquids as ligands - new catalysts for hydrosilylation processes

Principal investigator: prof. Hieronim Franciszek Maciejewski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Call: OPUS 8, Panel: ST5

126. Amine derivatives of hydantoin as selective 5-HT7 receptor ligand. Molecular modeling, synthesis and pharmacological eva…

Principal investigator: Katarzyna Maria Kucwaj-Brysz

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum Uniwersytet Jagielloński; Wydział Farmaceutyczny

Call: PRELUDIUM 8, Panel: NZ7

127. The effects of ligands of the alpha7 nicotinic acetylcholine receptors on complex cognitive processes and social behavio…

Principal investigator: Agnieszka Teresa Potasiewicz

Instytut Farmakologii PAN

Call: PRELUDIUM 8, Panel: NZ7

128. Induction of human colon cancer cells apoptosis in vitro and in vivo by Tumour Necrosis Factor-Related Apoptosis-Inducin…

Principal investigator: dr hab. Jarosław Tomasz Baran

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Call: OPUS 8, Panel: NZ5

129. Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap…

Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

130. Novel type modulators of purinergic receptors - Synthesis and study of receptor-ligand interaction

Principal investigator: prof. Zbigniew Jan Leśnikowski

Instytut Biologii Medycznej PAN

Call: OPUS 7, Panel: NZ1

131. An association of KIR, LILRB genes polymorphism and their ligands - HLA-C and HLA-G with recurrent implantation failure …

Principal investigator: dr hab. Izabela Nowak

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: OPUS 7, Panel: NZ5

132. Electronic coupling of nitric oxide with cobalt centers in various coordination environments: imact of electron density …

Principal investigator: Adam Andrzej Stępniewski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Call: PRELUDIUM 6, Panel: ST4

133. The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal r…

Principal investigator: prof. Grzegorz Władysław Hess

Instytut Farmakologii PAN

Call: OPUS 6, Panel: NZ4

134. Lanthanide complexes with chiral macrocyclic ligands - synthesis, chiral effects and its influence on the catalytic clea…

Principal investigator: Aleksandra Karolina Gerus

Uniwersytet Wrocławski, Wydział Chemii

Call: PRELUDIUM 6, Panel: ST5

135. Natural α-amino acids as highly efficient precursors of aminoaziridine ligands useful in asymmetric synthesis

Principal investigator: dr Adam Marek Pieczonka

Uniwersytet Łódzki, Wydział Chemii

Call: SONATA 6, Panel: ST5

136. The effect of probiotic bacteria and Toll-like receptors ligands on growth and differentiation of intestinal epithelial …

Principal investigator: dr hab. Małgorzata Krystyna Pierzchalska

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Technologii Żywności

Call: OPUS 5, Panel: NZ9

137. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application…

Principal investigator: Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: PRELUDIUM 5, Panel: NZ2

138. The mechanism of ligand binding and the conformational changes in the beta2-adrenergic receptor molecule

Principal investigator: dr Anita Płazińska

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

Call: SONATA 5, Panel: NZ2

139. A new transition metal complexes incorporating 2,3,5,6-tetra(2-pyridyl)pyrazine ligand in terms of structural, magnetic …

Principal investigator: dr Joanna Wanda Palion-Gazda

UNIWERSYTET ŚLĄSKI, Wydział Matematyki, Fizyki i Chemii

Call: PRELUDIUM 4, Panel: ST5

140. The new chiral diphosphine pinene derivatives as ligands for the enantioselective formation of C-N and C-C bonds

Principal investigator: dr Anna Kmieciak

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Call: PRELUDIUM 4, Panel: ST5

141. Electrokinetic characteristics of interaction between recombinant HSA monolayers and ionic ligands

Principal investigator: Marta Kujda

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Call: PRELUDIUM 4, Panel: ST5

142. Research of migration and transformation of aluminium forms in the transport of aluminium and its ligands from soil to l…

Principal investigator: dr hab. Marcin Frankowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Call: SONATA 4, Panel: NZ8

143. Synthesis and pharmacological properties of mono- di- and triheterocyclic azole derivatives as a hybrid receptor and PDE…

Principal investigator: prof. Maciej Henryk Pawłowski

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 4, Panel: NZ7

144. Metal-organic frameworks (MOFs) based on polytopic hydrazone ligands: synthesis, structure and physicochemical propertie…

Principal investigator: dr hab. Dariusz Matoga

Uniwersytet Jagielloński, Wydział Chemii

Call: OPUS 4, Panel: ST5

145. The search for a common structural motif in newly discovered ligands of human ficolin H - endotoxins of Proteus spp.

Principal investigator: dr Aleksandra Agnieszka Man-Kupisińska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: PRELUDIUM 4, Panel: NZ6

146. PHARMACOTHERAPY OF OSTEOARTHRITIS: TRPV1 AND CB1 RECEPTORS AND THEIR ENDOGENOUS LIGANDS AS NEW TARGETS FOR PHARMACOLOGIC…

Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

Instytut Farmakologii PAN

Call: SONATA BIS 2, Panel: NZ7

147. LCAP biomimetics - alicyclic amine derivatives as a new class of monoaminergic receptor ligands

Principal investigator: dr hab. Paweł Maria Zajdel

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 3, Panel: NZ7

148. Solution NMR investigations of human cystatin C - structure, dynamics and protein-ligand interactions.

Principal investigator: Martyna Ewa Maszota-Zieleniak

Uniwersytet Gdański, Wydział Chemii

Call: PRELUDIUM 2, Panel: ST4

149. The mast cell response to synthetic analogues of viral genomes (TLR3 and TLR7 ligands).

Principal investigator: dr Piotr Michał Witczak

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Call: PRELUDIUM 2, Panel: NZ6

150. Mechanisms of contact sensitivity response (CS) mediated via NK cells activated by Toll like receptor (TLR) ligands in m…

Principal investigator: dr Monika Majewska-Szczepanik

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Nauk o Zdrowiu

Call: OPUS 2, Panel: NZ6

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