Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Mechanisms of contact sensitivity response (CS) mediated via NK cells activated by Toll like receptor (TLR) ligands in mice.

2011/03/B/NZ6/00821

Keywords:

TLR PAMPS contact sensitivity reaction immunopotentiation anti-tumor immunity

Descriptors:

  • NZ6_1: Adaptive and innate immunity
  • NZ6_3: Animal immunology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Nauk o Zdrowiu

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Monika Majewska-Szczepanik 

Number of co-investigators in the project: 5

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 393 300 PLN

Project start date (Y-m-d): 2012-08-22

Project end date (Y-m-d): 2016-02-21

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. autoklaw (2 szt.) (80 000 PLN)
  2. komora Captair.

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (2)
  1. A subset of AID-dependent B-1a cells initiates hypersensitivity and pneumococcal pneumonia resistance.
    Authors:
    Philip W. Askenase, Krzysztof Bryniarski, Vipin Paliwal, Frank Redegeld, Thomas Groot Kormelink, Steven Kerfoot, Andrew T. Hutchinson, Henk van Loveren, Regin Campos, Atsuko Itakura, Monika Majewska-Szczepanik, Natsuo Yamamoto, Katarzyna Nazimek, Marian Szczepanik, Wold Ptak
    Academic press:
    Annals of the New York Academy of Sciences (rok: 2015, tom: 1362, strony: 200-2014), Wydawca: Wiley online Library
    Status:
    Published
    DOI:
    10.1111/nyas.12975. - link to the publication
  2. Expression of activation-induced cytidine deaminase enhances the clearance of pneumococcal pneumonia: evidence of a subpopulation of protective anti-pneumococcal B1a cells.
    Authors:
    Natsuo Yamamoto,2, Steven M. Kerfoot, Andrew T. Hutchinson, Charles S. Dela Cruz, Naomi Nakazawa, Marian Szczepanik, Monika Majewska-Szczepanik, Katarzyna Nazimek,4, Noboru Ohana, Krzysztof Bryniarski, Tsutomu Mori, Masamichi Muramatsu, Keiji Kanemitsu, Philip W. Askenase
    Academic press:
    Immunology (rok: 2016, tom: 147, strony: 97-113), Wydawca: Wiley online Library
    Status:
    Published
    DOI:
    10.1111/imm.12544. - link to the publication
  3. NK cell-mediated contact sensitivity develops rapidly and depends on IFN-α, IFN-γ and IL-12.
    Authors:
    Monika Majewska-Szczepanik, Silke Paust, Ulrich H. von Andrian, Philip W. Askenase, Marian Szczepanik
    Academic press:
    Immunology (rok: 2013, tom: 140, strony: 98-110), Wydawca: John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/imm.12120 - link to the publication
  4. Mechanizmy regulacji odpowiedzi immunologicznej w zwierzęcym modelu alergicznego kontaktowego zapalenia skóry.
    Authors:
    Anna Strzępa, Tomasz Stramek, Marian Szczepanik
    Academic press:
    Our Dermatology Online (rok: 2014, tom: 5 (Suppl. 1), strony: 327-332), Wydawca: Our Dermatology Online
    Status:
    Published
    DOI:
    10.7241/ourd.20144.84 - link to the publication
  5. Skin-induced tolerance as a new needle free therapeutic strategy.
    Authors:
    Marian Szczepanik
    Academic press:
    Pharmacological Reports (rok: 2014, tom: 66, strony: 192-197), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pharep.2013.09.001 - link to the publication
  1. NK cell mediated contact sensitivity develops rapidly and depends on IFN-a, IFN-g and IL-12
    Authors:
    Monika Majewska-Szczepanik, Silke Paust , Ulrich H. von Andrian , Philip W. Askenase and Marian Szczepanik
    Conference:
    XV Zjazd Polskiego Towarzystwa Immunologii Doświadczalnej i Klinicznej (rok: 2014, ), Wydawca: Termedia
    Data:
    konferencja 26.06.2014-28.06.2014
    Status:
    Published
  2. Participation of INKT cells in the early and late components of Tc1 mediated DNFB contact sensitivity: cooperative role of gd-Tcells
    Authors:
    Philip W. Askenase, Monika Majewska-Szczepanik, Steven Kerfoot , and Marian Szczepanik
    Conference:
    XV Zjazd Polskiego Towarzystwa Immunologii Doświadczalnej i Klinicznej (rok: 2014, ), Wydawca: Termedia
    Data:
    konferencja 26.06.2014-28.06.2014
    Status:
    Published

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