Development of method based on fluorescence polarization for high affinity ligand searching toward m7G nucleotide binding protein

2016/21/N/ST4/03750

Keywords

Descriptors

  • ST4_3: Metody spektroskopowe i spektrometryczne
  • ST4_4: Struktura i architektura molekularna
  • NZ1_3: Biofizyka

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Warszawski, Wydział Fizyki

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Anna Wojtczak

Number of co-investigators in the project: 2

Call

PRELUDIUM 11 – announced on 2016-03-15

Amount awarded
100 000 PLN
Project start date
2017-02-02
Project end date
2019-02-01
Project duration
24 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (1)

  1. Evaluation of carboxyfluorescein-labeled 7-methylguanine nucleotides as probes for studying cap-binding proteins by fluorescence anisotropy

    Authors:
    Anna Wojtczak, Renata Kasprzyk, Marcin Warmiński, Krystian Ubych, Dorota Kubacka, Pawel J. Sikorski, Jacek Jemielity, Joanna Kowalska
    Status:
    Accepted for publication

Articles in post-conference publications (3)

  1. Fluorescently labelled m7GpppG analogs as probes for fluorescence polarization studies – structure optimization and application

    Authors:
    Anna Nowicka, Marcin Warmiński, Renata Kasprzyk, Błażej Wojtczak, Dorota Kubacka, Joanna Kowalska, Jacek Jemielity
    Conference:
    XXIII INTERNATIONAL ROUNDTABLE ON NUCLEOSIDES, NUCLEOTIDES AND NUCLEIC ACIDS (year: 2018, pages: P36), Publisher: University of California, San Diego
    Date:
    conference 26-30.08.2018
    Status:
    Published
  2. PODEJŚCIE WYSOKOPRZEPUSTOWE DO POSZUKIWANIA LIGANDÓW BIAŁKA eIF4E JAKO INHIBITORÓW BIOSYNTEZY BIAŁKA

    Authors:
    Anna Nowicka, Renata Kasprzyk, Marcin Warmiński, Dorota Kubacka, Joanna Kowalska, Jacek Jemielity
    Conference:
    60 Zjazd naukowy Polskiego Towarzystwa Chemicznego (year: 2017, pages: 1020), Publisher: Polskie Towarzystwo Chemiczne
    Date:
    conference 17-21 września
    Status:
    Published
  3. Zastosowanie metody polaryzacji fluorescencji do poszukiwania silnych ligandów białek wiążących kap

    Authors:
    Anna Wojtczak, Renata kasprzyk, Dorota Kubacka, Radosław Wójcik, Marek R. Baranowski, Joanna Kowalska, Jacek Jemielity
    Conference:
    61. Zjazd Naukowy Polskiego Towarzystwa Chemicznego (year: 2018, pages: S08-16), Publisher: Polskie Towarzystwo Chemiczne
    Date:
    conference 17-21.09.2018
    Status:
    Published

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