Projects funded by the NCN
The effect of probiotic bacteria and Toll-like receptors ligands on growth and differentiation of intestinal epithelial cells - the studies on chicken embryo-derived organoids in three-dimensional culture
2013/09/B/NZ9/00285
Keywords:
innate immunity poultry feeding Toll-like receptors organoids three-dimensional cell culture enterocytes intestinal epithelium
Descriptors:
- NZ9_2: Animal production
- NZ1_8: Tissue engineering
- NZ1_9: Biotechnology
Panel:
NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation
Host institution :
Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Technologii Żywności
woj. małopolskie
Principal investigator (from the host institution):
dr hab. Małgorzata Pierzchalska
Number of co-investigators in the project: 5
Call: OPUS 5 - announced on 2013-03-15
Amount awarded: 496 048 PLN
Project start date (Y-m-d): 2014-02-10
Project end date (Y-m-d): 2018-01-09
Project duration:: 47 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Cieplarka z dopływem CO2 do hodowli komórkowej (20 000 PLN)
- Obiektyw mikroskopowy do fluorescencji immersyjny o powiększeniu 100x (15 000 PLN)
- Kolorowa kamera cyfrowa (14 000 PLN)
- doposażenie mikroskopu Zeiss (obiektyw 5x i ramka uniwersalna do stolika).
Information in the final report
- Publication in academic press/journals (4)
- Book publications / chapters in book publications (2)
- Probiotic Lactobacillus acidophilus bacteria or synthetic TLR2 agonist boost the growth of chicken embryo intestinal organoids in cultures comprising epithelial cells and myofibroblastsAuthors:Malgorzata Pierzchalska, Malgorzata Panek, Malgorzata Czyrnek, Anna Gielicz, Barbara Mickowska, Maja GrabackaAcademic press:Comparative Immunology, Microbiology and Infectious Diseases (rok: 2017, tom: 53, strony: 45491), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.cimid.2017.06.002 - link to the publication
- The formation of intestinal organoids in a hanging drop cultureAuthors:Malgorzata Panek, Maja Grabacka, Malgorzata PierzchalskaAcademic press:Cytotechnology (rok: 2018, tom: 70, strony: 1085-1095), Wydawca: Springer NetherlandsStatus:PublishedDOI:10.1007/s10616-018-0194-8 - link to the publication
- The potential role of some phytochemicals in recognition of mitochondrial damage-associated molecular patternsAuthors:Malgorzata Pierzchalska, Maja GrabackaAcademic press:Mitochondrion (rok: 2016, tom: 30, strony: 24-34), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.mito.2016.06.001 - link to the publication
- The migration and fusion events related to ROCK activity strongly influence the morphology of chicken embryo intestinal organoidsAuthors:Pierzchalska M., Panek M., Grabacka M.Academic press:Protoplasma (rok: 2019, tom: 256, strony: 575-581), Wydawca: SpringerStatus:PublishedDOI:10.1007/s00709-018-1312-3 - link to the publication
- The Three-Dimensional Culture of Epithelial Organoids Derived from Embryonic Chicken IntestineAuthors:Malgorzata Pierzchalska, Malgorzata Panek, Malgorzata Czyrnek, Maja GrabackaBook:ORGANOIDS: STEM CELLS, STRUCTURE AND FUNCTION (in Methods in Molecular Biology series) (rok: 2016, tom: -, strony: -), Wydawca: Humana PressStatus:Published
- Hodowle komórkowe nabłonka jelita w badaniach nad funkcjonalnymi właściwościami probiotykówAuthors:Małgorzata PanekBook:WYBRANE ZAGADNIENIA NAUKI O ŻYWNOŚCI I ŻYWIENIU (rok: 2016, tom: 2, strony: 58-70), Wydawca: Polskie Towarzystwo Technologów Żywności Oddział MałopolskiStatus:Published