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Information on the principal investigator and host institution

Information of the project and the call

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The mast cell response to synthetic analogues of viral genomes (TLR3 and TLR7 ligands).

2011/03/N/NZ6/03528

Keywords:

mast cells Toll-like receptors antiviral response

Descriptors:

  • NZ6_1: Adaptive and innate immunity

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Piotr Witczak 

Number of co-investigators in the project: 3

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 160 550 PLN

Project start date (Y-m-d): 2012-09-25

Project end date (Y-m-d): 2015-03-24

Project duration:: 30 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Mast cells generate cysteinyl leukotrienes and interferon-beta as well as evince impaired IgE-dependent degranulation upon TLR7 engagement
    Authors:
    Piotr Witczak, Anna Pietrzak, Karolina Wódz, Ewa Brzezińska-Błaszczyk
    Academic press:
    Indian Journal of Experimental Biology (rok: 2014, tom: 52, strony: 589-596), Wydawca: National Institute of Science Communication and Information Resources, CSIR
    Status:
    Published
    DOI:
    brak - link to the publication
  2. Toll-like receptors 3 ligation directly and indirectly affects mast cell cysteinyl leukotriene generation
    Authors:
    Piotr Witczak, Anna Pietrzak, Aleksandra Słodka, Ewa Brzezińska-Błaszczyk
    Academic press:
    Central European Journal of Immunology (rok: 2013, tom: 38, strony: 343-348), Wydawca: Termedia Sp. z o.o.
    Status:
    Published
    DOI:
    10.5114/ceji.2013.37755 - link to the publication
  1. TLR3- and TLR7-mediated phenotype alterations and interferon type I synthesis as an evidence for mast cell role in viral infections
    Authors:
    Piotr Witczak, Aleksandra Słodka, Ewa Brzezińska-Błaszczyk
    Conference:
    Biogenic Amines and Related Biologically Active Compounds (rok: 2014, ), Wydawca: Polskie Towarzystwo Badań nad Histaminą
    Data:
    konferencja 23-25.10.2014
    Status:
    Published
    DOI:
    link to the publication
  2. Mast cells generate cysteinyl leukotrienes and exhibit altered IgE-dependent releasability upon TLR3 and TLR7-mediated activation
    Authors:
    Piotr Witczak, Aleksandra Słodka, Edyta Bąbolewska, Karolina Wódz, Ewa Brzezińska-Błaszczyk
    Conference:
    The European Histamine Research Society 42nd Annual Meeting (rok: 2013, ), Wydawca: Springer
    Data:
    konferencja 8-11.05.2013
    Status:
    Published
    DOI:
    link to the publication

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