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An association of KIR, LILRB genes polymorphism and their ligands - HLA-C and HLA-G with recurrent implantation failure after in vitro fertilization.

2014/13/B/NZ5/00273

Keywords

Descriptors

  • NZ5_1: Etiologia chorób człowieka
  • NZ5_5: Diagnostyka chorób człowieka
  • NZ6_2: Immunologia kliniczna

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Izabela Nowak

Number of co-investigators in the project: 5

Call

OPUS 7 – announced on 2014-03-17

Amount awarded
1 002 600 PLN
Project start date
2015-02-18
Project end date
2020-02-17
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (4)

  1. Association of Soluble HLA-G Plasma Level and HLA-G Genetic Polymorphism With Pregnancy Outcome of Patients Undergoing in vitro Fertilization Embryo Transfer

    Authors:
    Nowak I, Wilczyńska K, Radwan P, Wiśniewski A, Krasiński R, Radwan M, Wilczyński JR, Malinowski A, Kuśnierczyk P.
    Academic press:
    Frontiers in Immunology (year: 2020, volume: 10, pages: 2982), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2019.02982. – link to the publication

  2. KIR, LILRB and their ligands' genes as potential biomarkers in recurrent implantation failure

    Authors:
    Izabela Nowak, Karolina Wilczyńska, Jacek R. Wilczyński, Andrzej Malinowski, Paweł Radwan, Michał Radwan, Piotr Kuśnierczyk
    Academic press:
    Archivum Immunologiae et Therapiae Experimentalis (year: 2017, volume: 65 (5), pages: 391-399), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00005-017-0474-6 – link to the publication

  3. The methylenetetrahydrofolate reductase c.c.677 C>T and c.c.1298 A>C polymorphisms in reproductive failures: Experience from an RSA and RIF study on a Polish population.

    Authors:
    Nowak I, Bylińska A, Wilczyńska K, Wiśniewski A, Malinowski A, Wilczyński JR, Radwan P, Radwan M, Barcz E, Płoski R, Motak-Pochrzęst H, Banasik M, Sobczyński M, Kuśnierczyk P.
    Academic press:
    PLoS ONE (year: 2017, volume: Oct 26;12(10), pages: e0186022), Publisher: PLOS
    Status:
    Published
    DOI:
    10.1371/journal.pone.0186022 – link to the publication

  4. KIR and HLA-C genes in male infertility

    Authors:
    Karolina Wilczyńska, Paweł Radwan, Rafał Krasiński, Michał Radwan, Jacek R. Wilczyński, Andrzej Malinowski, Ewa Barcz, Izabela Nowak
    Academic press:
    Journal of Assisted Reproduction and Genetics (year: 2020, volume: 46162, pages: Online ahead of print), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s10815-020-01814-6 – link to the publication

Articles in post-conference publications (7)

  1. Recurrent implantation failure and soluble HLA-G plasma levels

    Authors:
    Andrzej Wiśniewski, Karolina Wilczyńska, Rafał Krasiński, Paweł Radwan, Michał Radwan, Jacek R. Wilczyński,Andrzej Malinowski, Piotr Kuśnierczyk, Izabela Nowak
    Conference:
    The XVIth Congress of the Polish Society of Experimenthal and Clinical Immunology, Warszawa 2017 (year: 2017, pages: 74), Publisher: Termedia Publishing House Ltd.
    Date:
    conference 8-10.06.
    Status:
    Published

  2. New insights into HLA-G promoter genotyping

    Authors:
    Andrzej Wiśniewski, Marta Wagner, Andrzej Malinowski, Jacek R. Wilczyński, Michał Radwan, Paweł Radwan, Piotr Kuśnierczyk, Izabela Nowak
    Conference:
    10th East-West Immunogenetics Conference (EWIC) Wrocław 2016 (year: 2016, pages: S3-S36), Publisher: Springer
    Date:
    conference 21.04.-23.04.2016
    Status:
    Published

  3. Killer cell immunoglobulin-like receptor and HLA-C polymorphisms in recurrent implantation failure

    Authors:
    Karolina Wilczyńska, Paweł Radwan, Michał Radwan, Jacek R. Wilczyński, Andrzej Malinowski, Ewa Barcz, Rafał Płoski, Piotr Kuśnierczyk, Izabela Nowak
    Conference:
    32nd European Immunogenetics and Histocompatibility Conference, Venice Lido Italy 2018 (year: 2018, pages: 463), Publisher: Willey, HLA. 2018;91:354–474.
    Date:
    conference 9.05.-12.05
    Status:
    Published

  4. Killer cell immunoglobulin-like receptor genes polymorphism in recurrent implantation failure following in vitro fertilization – a preliminary study

    Authors:
    Izabela Nowak, Karolina Wilczyńska, Adriana Jakubowska, Andrzej Malinowski, Jacek R. Wilczyński, Michał Radwan, Paweł Radwan, Piotr Kuśnierczyk
    Conference:
    V Polski Kongres Genetyki Łodź 2016 (year: 2016, pages: 179), Publisher: Polskie Towarzystwo Genetyczne, Polskie Towarzystwo Genetyki Człowieka
    Date:
    conference 19-22.09.
    Status:
    Published

  5. The study of genetic polyrnorphisrns for KIR2DL4, LILRB1, LILRB2 receptors and their ligand - HLA-G in recurrent implantation failure

    Authors:
    K. Wilczyńska, M. Jasek, M. Wagner, W. Niepiekło-Miniewska, A. Wiśniewski, P. Radwan, M. Radwan, J.R. Wilczyński, A. Malinowski, P. Kuśnierczyk, I. Nowak
    Conference:
    14th Conference of the European Society for Reproductive Immunology, Kos Greece 2017 (year: 2017, pages: 37-50), Publisher: Elsevier
    Date:
    conference 29.09-2.10.
    Status:
    Published

  6. Recurrent implantation failure and soluble HLA-G plasma levels

    Authors:
    Wilczyńska K, Wiśniewski W, Krasiński R, Radwan P, Radwan M, Wilczyński JR, Malinowski A, Kuśnierczyk P, Nowak I.
    Conference:
    14th Conference of the European Society for Reproductive Immunology, Kos Greece 2017 (year: 2017, pages: 37-50), Publisher: Elsevier
    Date:
    conference 29.09-2.10.
    Status:
    Published

  7. Methylenetetrahydrofolate reductase polymorphisms and a risk of reproductive failures in Polish population

    Authors:
    Izabela Nowak, Aleksandra Bylińska, Andrzej Malinowski, Jacek R. Wilczyński, Paweł Radwan, Michał Radwan, Ewa Barcz, Piotr Kuśnierczyk
    Conference:
    The XVIth Congress of the Polish Society of Experimental and Clinical Immunology, Warszawa 2017 (year: 2017, pages: 78-79), Publisher: Termedia Publishing House Ltd.
    Date:
    conference 8-10.06.
    Status:
    Published

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